Catalog No.
YHF86601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr144-Met324
Predicted molecular weight
23.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01432
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AMP deaminase 3, 3.5.4.6, AMP deaminase isoform E, Erythrocyte AMP deaminase, AMPD3
AMPD3 promotes doxorubicin-induced cardiomyopathy through HSP90α-mediated ferroptosis., PMID:39474068
Molecular characterization of adenosine monophosphate deaminase 1 and the correlation analysis between its mRNA expression levels and inosine monophosphate content in large yellow croaker (Larimichthys crocea)., PMID:38452850
Proteomic-metabolomic combination analysis reveals novel biomarkers of meat quality that differ between young and older ducks., PMID:38417328
Analysis of metabolome and transcriptome of longissimus thoracis and subcutaneous adipose tissues reveals the regulatory mechanism of meat quality in MSTN mutant castrated male finishing pigs., PMID:37864922
Erythrocyte ENT1-AMPD3 Axis is an Essential Purinergic Hypoxia Sensor and Energy Regulator Combating CKD in a Mouse Model., PMID:37725437
Dietary intake of fructose increases purine de novo synthesis: A crucial mechanism for hyperuricemia., PMID:36601078
Potential shared gene signatures and molecular mechanisms between atherosclerosis and depression: Evidence from transcriptome data., PMID:36565484
Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia., PMID:35460704
Rare variants in previously identified linkage regions associated with carotid plaque in Dominican Republic families., PMID:35020748
AMP deamination is sufficient to replicate an atrophy-like metabolic phenotype in skeletal muscle., PMID:34400216
Adenosine monophosphate deaminase 3 null mutation causes reduction of naive T cells in mouse peripheral blood., PMID:32761233
Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease., PMID:32694829
Increased AMP deaminase activity decreases ATP content and slows protein degradation in cultured skeletal muscle., PMID:32370945
Ovarian cancer detection by DNA methylation in cervical scrapings., PMID:31775891
Gut microbiota regulates mouse behaviors through glucocorticoid receptor pathway genes in the hippocampus., PMID:30194287
Role of the HPRG Component of Striated Muscle AMP Deaminase in the Stability and Cellular Behaviour of the Enzyme., PMID:30142952
Translational regulation by miR-301b upregulates AMP deaminase in diabetic hearts., PMID:29733818
Role of Low-Molecular-Mass Penicillin-Binding Proteins, NagZ and AmpR in AmpC β-lactamase Regulation of Yersinia enterocolitica., PMID:29021974
New insights on the regulation of the adenine nucleotide pool of erythrocytes in mouse models., PMID:28746349
AMPD3 is associated with the malignant characteristics of gastrointestinal stromal tumors., PMID:28454247
Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study., PMID:28250428
Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion., PMID:27991918
Adenosine monophosphate deaminase 3 activation shortens erythrocyte half-life and provides malaria resistance in mice., PMID:27465915
Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for GI Infection, IBD, POI, Neurological, Motility, and GI Disorders., PMID:27416040
Meta-analysis of genome-wide association studies identifies three novel loci for saturated fatty acids in East Asians., PMID:26932504
CD73 and AMPD3 deficiency enhance metabolic performance via erythrocyte ATP that decreases hemoglobin oxygen affinity., PMID:26249166
AMP deaminase 3 deficiency enhanced 5'-AMP induction of hypometabolism., PMID:24066180
AMP deaminase 3 plays a critical role in remote reperfusion lung injury., PMID:23542464
AMPD3-deficient mice exhibit increased erythrocyte ATP levels but anemia not improved due to PK deficiency., PMID:23078545
AMPD3 is involved in anthrax LeTx-induced macrophage cell death., PMID:21822801
New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC., PMID:19253308
Expression patterns of AMP-deaminase isozymes in human hepatocellular carcinoma (HCC)., PMID:18493842
[AMPD genes and urate metabolism]., PMID:18409530
Expression patterns of AMP-deaminase and cytosolic 5'-nucleotidase genes in human term placenta., PMID:18165923
Remote reperfusion lung injury is associated with AMP deaminase 3 activation and attenuated by inosine monophosphate., PMID:17384464
Effect of Akt inhibition on scatter factor-regulated gene expression in DU-145 human prostate cancer cells., PMID:17099727
Cultured interstitial cells from human heart valves express both specific skeletal muscle and non-muscle markers., PMID:16154797
Calcium activates erythrocyte AMP deaminase [isoform E (AMPD3)] through a protein-protein interaction between calmodulin and the N-terminal domain of the AMPD3 polypeptide., PMID:15807549
Distinctive gene expression of human lung adenocarcinomas carrying LKB1 mutations., PMID:15077168
N-terminal sequence and distal histidine residues are responsible for pH-regulated cytoplasmic membrane binding of human AMP deaminase isoform E., PMID:12213808
Localization of N-terminal sequences in human AMP deaminase isoforms that influence contractile protein binding., PMID:11444869
Regulation of AMP deaminase by phosphoinositides., PMID:10464307
Novel aspects of tetramer assembly and N-terminal domain structure and function are revealed by recombinant expression of human AMP deaminase isoforms., PMID:9857047
Molecular analysis of mouse Ampd3 gene encoding heart-type isoform of AMP deaminase., PMID:9598087
Genomic organization of Ampd3, heart-type AMPD gene, located in mouse chromosome 7., PMID:9321472
Regulation of rat AMP deaminase 3 (isoform C) by development and skeletal muscle fibre type., PMID:9291127
Cloning and expression of cDNA encoding heart-type isoform of AMP deaminase., PMID:9133604
Subunit composition of AMPD varies in response to changes in AMPD1 and AMPD3 gene expression in skeletal muscle., PMID:8863347
Characterization of the human AMPD3 gene reveals that 5' exon useage is subject to transcriptional control by three tandem promoters and alternative splicing., PMID:8611627
Molecular biology of AMP deaminase deficiency., PMID:8032342
For research use only. Not for human or drug use.
