Catalog No.
YHE96501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr151-Gly210
Predicted molecular weight
35.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52945
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, PDX1, IPF1, STF1
Anti-CTGF/PD-1 bispecific antibody Y126S restrains desmoplastic and immunosuppressive microenvironment in pancreatic cancer., PMID:40514068
SIRT1 Regulates Iron Metabolism to Attenuate β-Cell Dedifferentiation by Inhibiting FoxO1 Acetylation., PMID:40512369
METRNL represses beta-to-alpha cell trans-differentiation to maintain beta cell function under diabetic metabolic stress in mice., PMID:40495021
Neonatal diabetes-associated missense PDX1 variant disrupts chromatin association and protein-protein interaction., PMID:40485586
CK2 regulates somatostatin expression in pancreatic delta cells., PMID:40474387
Macrophage activation determines muscle wasting in pancreatic cancer., PMID:40442475
PDX1 in early pregnancy is associated with decreased risks of gestational diabetes mellitus and adverse pregnancy outcomes., PMID:40405977
Adiponectin: its role in diabetic and pancreatic cancer., PMID:40403652
[Association and mechanism between genetic variants in binding region of pancreatic and duodenum homeobox-1 and susceptibility to pancreatic cancer]., PMID:40374346
Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway., PMID:40365319
Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development., PMID:40330128
Mechanosensitive Channels Mediate Pancreatic β Cells Reactive Oxygen Species Formation and Downregulation of Essential Genes During Therapeutic Ultrasound Treatment., PMID:40310296
Long-Term Administration of Antioxidant N-Acetyl-L-Cysteine Impacts Beta Cell Oxidative Stress, Insulin Secretion, and Intracellular Signaling Pathways in Aging Mice., PMID:40298742
Mg2+ Supplementation Mitigates Metabolic Deficits Associated With TRPM7 Disruption., PMID:40275767
Therapeutic effects and mechanisms of Xinmaitong formula for type 2 diabetes mellitus via GLP-1R signaling., PMID:40271065
Do human adipose stem cell-derived artificial insulin-producing cells develop tumorigenic characteristics throughout differentiation?, PMID:40253677
PPY-Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer., PMID:40162859
Oncogenic small extracellular vesicles enriched in sphingosine-1-phosphate play a crucial role in pancreatic cancer progression., PMID:40158707
Placental extract augments mesenchymal stem cells in pancreatic tissue regeneration: A new insight into diabetes treatment., PMID:40157219
Rhoifolin Improves Glycometabolic Control in Streptozotocin-Induced Diabetic Rats by Up-Regulating the Expression of Insulin Signaling Proteins and Down-Regulating the MAPK/JNK Pathway., PMID:40143138
Enhancement of functional insulin-producing cell differentiation from embryonic stem cells through MST1-silencing., PMID:40108649
Cannabidiol oil delays pancreatic islet dysfunction in Wistar rats under hypercaloric diet., PMID:40106970
Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management., PMID:40076938
Propionyl-CoA carboxylase subunit B regulates anti-tumor T cells in a pancreatic cancer mouse model., PMID:40067762
Integrative genome-wide aberrant DNA methylation and transcriptome analysis identifies diagnostic markers for colorectal cancer., PMID:40059124
The Insulin-Producing Cells Generated from Rat Adipose Tissue Mesenchymal Stem Cells via Pdx1 Overexpression Activate an Immune Response both in Vitro and in Vivo., PMID:40026296
AG73-GelMA/AlgMA hydrogels provide a stable microenvironment for the generation of pancreatic progenitor organoids., PMID:40016740
Type 1 Diabetes Risk Variants Reduce Beta Cell Function., PMID:40004501
Single Low-Dose Ionizing Radiation Transiently Enhances Rat RIN-m5F Cell Function via the ROS/p38 MAPK Pathway Without Inducing Cell Damage., PMID:40002307
Mitogen-Activated Protein Kinase Phosphatase-2 Deletion Promotes Hyperglycemia and Susceptibility to Streptozotocin-Induced Diabetes in Female Mice In Vivo., PMID:39996734
SRSF12 deficiency enhances tumor innervation and accelerates pancreatic tumorigenesis., PMID:39986371
The assembled decoders to prepare for "bioactive X″ against progressive deterioration of liver disease: From NAFLD to HCC., PMID:39970728
Gut-pancreas axis in the control of insulin secretion in streptozotocin-resistant rats., PMID:39955952
Retinoic acid receptor-β deletion in a model of early pancreatic ductal adenocarcinoma (PDAC) tumorigenesis., PMID:39949931
Recent advances in pancreatic α-cell transdifferentiation for diabetes therapy., PMID:39911402
Vitamin D augments insulin secretion via calcium influx and upregulation of voltage calcium channels: Findings from INS-1 cells and human islets., PMID:39864489
Genetic Structure of Hereditary Forms of Diabetes Mellitus in Russia., PMID:39859454
Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System., PMID:39828973
Pancreatic expression of CPT1A is essential for whole body glucose homeostasis by supporting glucose-stimulated insulin secretion., PMID:39814231
Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9., PMID:39806513
Temporal increase in Ki-67 index in patients with pancreatic neuroendocrine tumours., PMID:39804242
Engineering Gene and Protein Switches for Regulation of Lineage-Specifying Transcription Factors., PMID:39801452
E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic β cells., PMID:39797759
The Glucose-Lowering Effect of Mesembryanthemum crystallinum and D-Pinitol: Studies on Insulin Secretion in INS-1 Cells and the Reduction of Blood Glucose in Diabetic Rats., PMID:39796627
The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells., PMID:39791758
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control., PMID:39788719
The RNA-binding protein HuR impairs adipose tissue anabolism in pancreatic cancer cachexia., PMID:39763867
Orthogonal and multiplexable genetic perturbations with an engineered prime editor and a diverse RNA array., PMID:39737993
VPS41 deletion triggers progressive loss of insulin stores and downregulation of β-cell identity., PMID:39716868
γ-Glutamylcysteine restores glucolipotoxicity-induced islet β-cell apoptosis and dysfunction via inhibiting endoplasmic reticulum stress., PMID:39701215
For research use only. Not for human or drug use.
