Catalog No.
YHE20102
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu2-Lys226
Predicted molecular weight
39.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P36957
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial, 2.3.1.61, 2-oxoglutarate dehydrogenase complex component E2, OGDC-E2, Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex, E2K, DLST, DLTS
Cuproptosis-related gene signatures define the immune microenvironment in diabetic nephropathy., PMID:40460381
Succinate drives gut inflammation by promoting FOXP3 degradation through a molecular switch., PMID:40457062
A lncRNA-mediated metabolic rewiring of cell senescence., PMID:40408249
Copper's new role in cancer: how cuproptosis-related genes could revolutionize glioma treatment., PMID:40355831
Copper oxide nanoparticles induce pulmonary inflammation via triggering cellular cuproptosis., PMID:40180017
Novel comparative analysis and equation development for body volume estimation using dual-energy x-ray absorptiometry in athletes., PMID:40119135
Knocking Down Ferredoxin 1 Inhibits the Progression of Colorectal Cancer and Regulates Cuproptosis via Mediating the Hippo Signaling Pathway., PMID:39987563
Protein identification using Cryo-EM and artificial intelligence guides improved sample purification., PMID:39958810
Cuproptosis gene characterizes the immune microenvironment of diabetic nephropathy., PMID:39892769
The study on cuproptosis in Alzheimer's disease based on the cuproptosis key gene FDX1., PMID:39759399
Bioinformatics and Machine Learning-Based Identification of Critical Biomarkers and Immune Infiltration in Venous Thromboembolism., PMID:39618481
[The role of peritumoral electroacupuncture in regulating cuproptosis for sensitization of chemotherapy efficacy in mice with triple-negative breast cancer]., PMID:39557431
Inhibition of CTR1 expression improves hypoxia/reoxygenation-induced myoblast injury by blocking cuproptosis., PMID:39418771
Proteomics Analysis of Human Chorionic Villi Reveals Dysregulated Pathways That Contribute to Recurrent Pregnancy Loss., PMID:39182192
Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells., PMID:39053638
Multi-omics revealed anti-fatigue property of polyphenol from areca nut., PMID:38964153
ABCD4 is associated with mammary gland development in mammals., PMID:38764031
Environmental copper exposure, placental cuproptosis, and miscarriage., PMID:38552771
[Three Cases of Febrile Reactions after Using Oxaliplatin]., PMID:38247081
Bioinformatics analysis and experimental validation reveal the anti-ferroptosis effect of FZD7 in acute kidney injury., PMID:38071893
Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency., PMID:37883842
Bioinformatics analysis of copper death gene in diabetic immune infiltration., PMID:37773841
MYOD induced lnc-MEG3 promotes porcine satellite cell differentiation via interacting with DLST., PMID:37506369
Evolutionary trajectories of beta-lactamase NDM and DLST cluster in Pseudomonas aeruginosa: finding the putative ancestor., PMID:37464884
Clarithromycin-induced eosinophilic granulomatosis with polyangiitis: A case report., PMID:37305218
The impact of RNA binding proteins and the associated long non-coding RNAs in the TCA cycle on cancer pathogenesis., PMID:37221841
DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation and metabolic remodeling., PMID:37139660
The potential value of cuprotosis in myocardial immune infiltration that occurs in pediatric congenital heart disease in response to surgery with cardiopulmonary bypass., PMID:36988255
Bioinformatics analysis and experimental validation of cuproptosis-related lncRNA LINC02154 in clear cell renal cell carcinoma., PMID:36797708
4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to promote cuproptosis in colorectal cancer., PMID:36706634
ATF3/SPI1/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury., PMID:36675183
Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels., PMID:36634214
Cuproptosis is involved in copper-induced hepatotoxicity in chickens., PMID:36621474
Proteomic analysis revealed the pharmacological mechanism of Xueshuantong injection in preventing early acute myocardial infarction injury., PMID:36618918
The concentrations of antibodies to Epstein-Barr virus decrease during ocrelizumab treatment., PMID:36603289
Prognostic and immune correlation evaluation of a novel cuproptosis-related genes signature in hepatocellular carcinoma., PMID:36588699
A novel cuproptosis-related gene signature of prognosis and immune microenvironment in head and neck squamous cell carcinoma cancer., PMID:36376617
Identification of Genes and Metabolic Pathways Involved in Resin Yield in Masson Pine by Integrative Analysis of Transcriptome, Proteome and Biochemical Characteristics., PMID:36232722
Effects of Luteolin on Human Breast Cancer Using Gene Expression Array: Inferring Novel Genes., PMID:35678671
Functional identification of microRNA-centered complexes in C. elegans., PMID:35504914
In silico analyses of penicillin binding proteins in Burkholderia pseudomallei uncovers SNPs with utility for phylogeography, species differentiation, and sequence typing., PMID:35417451
The mitochondrial proteomic changes of rat hippocampus induced by 28-day simulated microgravity., PMID:35271667
Tubulointerstitial nephritis and uveitis syndrome following meningitis and systemic lymphadenopathy with persistent Toxoplasma immunoglobulin M: a case report., PMID:34556154
Transcriptome analysis revealed multiple immune processes and energy metabolism pathways involved in the defense response of the large yellow croaker Larimichthys crocea against Pseudomonas plecoglossicida., PMID:34418783
A complicated case of Serratia marcescens catheter-related bloodstream infection misdiagnosed as hypersensitivity reactions to bicarbonate dialysate containing acetate., PMID:34302598
Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma., PMID:34233924
Ovarian cancer modulates the immunosuppressive function of CD11b+Gr1+ myeloid cells via glutamine metabolism., PMID:34144215
Identification of New Rare Variants Associated With Familial Autoimmune Thyroid Diseases by Deep Sequencing of Linked Loci., PMID:34143178
Germline DLST Variants Promote Epigenetic Modifications in Pheochromocytoma-Paraganglioma., PMID:33180916
Pioglitazone corrects dysregulation of skeletal muscle mitochondrial proteins involved in ATP synthesis in type 2 diabetes., PMID:33137378
For research use only. Not for human or drug use.
