Catalog No.
YHD83001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Arg84
Predicted molecular weight
23.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29371
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neuromedin-K receptor, NKR, NK-3 receptor, NK-3R, Neurokinin B receptor, Tachykinin receptor 3, TACR3, NK3R, TAC3R
The Biological Properties of the FAS and TACR3 Genes and the Association of Single-Nucleotide Polymorphisms with Milk Quality Traits in Gannan Yak., PMID:40361657
17β-Trenbolone modulates anxiety-related synaptic plasticity by affecting the interaction between hippocampal TACR3 and systemic testosterone in male mice., PMID:40340005
Sex-specific skeletal muscle gene expression responses to exercise reveal novel direct mediators of insulin sensitivity change., PMID:40225320
Elucidating the mechanism of phthalates induced osteoporosis through network toxicology and molecular docking., PMID:39884015
Noval insights and therapeutic strategies for tumor-induced kidney pathologies., PMID:39427201
Homozygous mutation of KISS1 receptor (KISS1R) gene identified in a Chinese patient with congenital hypogonadotropic hypogonadism (CHH): case report and literature review., PMID:39262158
Lack of a genetic risk continuum between pubertal timing in the general population and idiopathic hypogonadotropic hypogonadism., PMID:39256164
Variety of genetic defects in GnRH and hypothalamic-pituitary signaling and development in normosmic patients with IHH., PMID:39010903
Decoding the effect of photoperiodic cues in transducing kisspeptin-melatonin circuit during the pubertal onset in common carp., PMID:38800960
Estrogen promotes gonadotropin-releasing hormone expression by regulating tachykinin 3 and prodynorphin systems in chicken., PMID:38759565
Interplay between hippocampal TACR3 and systemic testosterone in regulating anxiety-associated synaptic plasticity., PMID:38135756
TAC3 regulates GnRH/gonadotropin synthesis in female chickens., PMID:38128223
Transcriptional profiling of Kiss1 neurons from arcuate and rostral periventricular hypothalamic regions in female mice., PMID:37934722
A diagnostic model for sepsis-induced acute lung injury using a consensus machine learning approach and its therapeutic implications., PMID:37700323
Are novel treatments for brain disorders hiding in plain sight?, PMID:37422511
Diurnal regulation of metabolism by Gs-alpha in hypothalamic QPLOT neurons., PMID:37141220
Genetic variants of G-protein coupled receptors associated with pubertal disorders., PMID:37122876
Tachykinin receptor 3 in the lateral habenula alleviates pain and anxiety comorbidity in mice., PMID:36756128
ATAC-seq and RNA-seq analysis unravel the mechanism of sex differentiation and infertility in sex reversal chicken., PMID:36617567
Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders., PMID:36581877
Screening of the siGPCR library in combination with cisplatin against lung cancers., PMID:36253428
An integrative analysis of DNA methylation and gene expression to predict lung adenocarcinoma prognosis., PMID:36105089
TAC3/TACR3 System Function in the Catadromous Migration Teleost, Anguilla japonica., PMID:35937808
Genetic validation of neurokinin 3 receptor antagonists for ischemic heart disease prevention in men - A one-sample Mendelian randomization study., PMID:35231698
Regional genotypic variations in normosmic congenital hypogonadotropic hypogonadism: our experience and systematic review., PMID:35133534
Genetic factors in precocious puberty., PMID:34665958
The potential cytotoxic effects of urban particle matter on olfaction., PMID:34636368
Local administration of Neurokinin B in the arcuate nucleus accelerates the neural activity of the GnRH pulse generator in goats., PMID:34629331
Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease., PMID:33637690
Molecular targets for endogenous glial cell line-derived neurotrophic factor modulation in striatal parvalbumin interneurons., PMID:32954345
Tacr3/NK3R: Beyond Their Roles in Reproduction., PMID:32926772
Female infertility is associated with an altered expression of the neurokinin B/neurokinin B receptor and kisspeptin/kisspeptin receptor systems in ovarian granulosa and cumulus cells., PMID:32811673
The potential implication of neurokinin B in the modulation of prolactin secretion at the pituitary level in cyclic gilts., PMID:32776908
Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats., PMID:32281549
Tacr3 in the lateral habenula differentially regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia., PMID:32264959
Genes regulating hormone stimulus and response to protein signaling revealed differential expression pattern during porcine oocyte in vitro maturation, confirmed by lipid concentration., PMID:32189110
A single-nucleotide polymorphism induced alternative splicing in Tacr3 involves in hypoxic-ischemic brain damage., PMID:31722250
Sexually dimorphic gene expression and neurite sensitivity to estradiol in fetal arcuate Kiss1 cells., PMID:31671405
IGFs Potentiate TAC3-induced SLα Expression via Upregulation of TACR3 Expression in Grass Carp Pituitary Cells., PMID:31412674
Transcriptomic Pattern of Genes Regulating Protein Response and Status of Mitochondrial Activity Are Related to Oocyte Maturational Competence-A Transcriptomic Study., PMID:31067669
Glutamatergic Neurokinin 3 Receptor Neurons in the Median Preoptic Nucleus Modulate Heat-Defense Pathways in Female Mice., PMID:30753503
LOC134466 methylation promotes oncogenesis of endometrial carcinoma through LOC134466/hsa-miR-196a-5p/TAC1 axis., PMID:30485833
A novel stopgain mutation c.G992A (p.W331X) in TACR3 gene was identified in nonobstructive azoospermia by targeted next-generation sequencing., PMID:30390321
Altered expression of the kisspeptin/KISS1R and neurokinin B/NK3R systems in mural granulosa and cumulus cells of patients with polycystic ovarian syndrome., PMID:30382469
Burden Testing of Rare Variants Identified through Exome Sequencing via Publicly Available Control Data., PMID:30269813
Silver Nanoparticle Exposure Induces Neurotoxicity in the Rat Hippocampus Without Increasing the Blood-Brain Barrier Permeability., PMID:29944106
GnRH receptor gene mutations in adolescents and young adults presenting with signs of partial gonadotropin deficiency., PMID:29182666
Molecular genetic and clinical delineation of 22 patients with congenital hypogonadotropic hypogonadism., PMID:28915117
Role of G protein-coupled receptors-microRNA interactions in gastrointestinal pathophysiology., PMID:28774868
For research use only. Not for human or drug use.
