Catalog No.
YHD69201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr150-Thr392
Predicted molecular weight
28.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26010
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Integrin beta-7, Gut homing receptor beta subunit, ITGB7
Repercussions of the Calpain Cleavage-Related Missense Mutations in the Cytosolic Domains of Human Integrin-β Subunits on the Calpain-Integrin Signaling Axis., PMID:40362482
A novel mechanism of kisspeptin regulating ovarian granulosa cell function via down-regulating let-7b to activate ERK/PI3K-Akt pathway in Tan sheep., PMID:40354677
Targeting molecular pathways to control immune checkpoint inhibitor toxicities., PMID:39732529
Dan'e fukang decoction reduces hemorrhage in a rat model of mifepristone induced incomplete abortion and may correlate with cell adhesion molecule signaling interference., PMID:39461386
Plasma proteome mediate the impact of PM2.5 on stroke: A 2-step Mendelian randomization study., PMID:38908058
Cryo-EM structure of I domain-containing integrin αEβ7., PMID:38781659
KMT2D regulates activation, localization, and integrin expression by T-cells., PMID:38765012
Establishment of a patient-specific avatar organoid model derived from EUS-guided fine-needle biopsy for timely clinical application in pancreatic ductal adenocarcinoma (with video)., PMID:38447660
MET receptor serves as a promising target in melanoma brain metastases., PMID:38386085
Bruceine B Displays Potent Antimyeloma Activity by Inducing the Degradation of the Transcription Factor c-Maf., PMID:38230274
Col1a1 mediates the focal adhesion pathway affecting hearing in miR-29a mouse model by RNA-seq analysis., PMID:38103809
Identification of small compounds that inhibit multiple myeloma proliferation by targeting c-Maf transcriptional activity., PMID:37879249
Identification of immune infiltration-related biomarkers in carotid atherosclerotic plaques., PMID:37644056
Prognostic value and potential molecular mechanism of ITGB superfamily members in hepatocellular carcinoma., PMID:37603520
Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia., PMID:37359019
IL-3 produced by T cells is crucial for basophil extravasation in hapten-induced allergic contact dermatitis., PMID:37180157
Establishment and validation of a novel integrin-based prognostic gene signature that sub-classifies gliomas and effectively predicts immunosuppressive microenvironment., PMID:37096960
Mild heat stress-induced adaptive immune response in blood mononuclear cells and leukocytes from mesenteric lymph nodes of primiparous lactating Holstein cows., PMID:36894431
Immune cell-specific smoking-related expression characteristics are revealed by re-analysis of transcriptomes from the CEDAR cohort., PMID:36817262
Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics., PMID:36737807
The prognostic and immune infiltration role of ITGB superfamily members in non-small cell lung cancer., PMID:36247270
In silico development and experimental validation of a novel 7-gene signature based on PI3K pathway-related genes in bladder cancer., PMID:35896848
Transcriptomic landscape of sodium butyrate-induced growth inhibition of human colorectal cancer organoids., PMID:35837877
Targeting the oncogenic transcription factor c-Maf for the treatment of multiple myeloma., PMID:35700821
Chitosan oligosaccharide improves the mucosal immunity of small intestine through activating SIgA production in mice: Proteomic analysis., PMID:35569308
The transcription factor LRF promotes integrin β7 expression by and gut homing of CD8αα+ intraepithelial lymphocyte precursors., PMID:35354951
Identification of Therapeutic Targets and Prognostic Biomarkers Among Integrin Subunits in the Skin Cutaneous Melanoma Microenvironment., PMID:34660316
Vitamin D Is Associated with α4β7+ Immunophenotypes and Predicts Vedolizumab Therapy Failure in Patients with Inflammatory Bowel Disease., PMID:34180967
Integrated analysis reveals the participation of IL4I1, ITGB7, and FUT7 in reshaping the TNBC immune microenvironment by targeting glycolysis., PMID:34134578
Integrin β7 Inhibits Colorectal Cancer Pathogenesis via Maintaining Antitumor Immunity., PMID:34131019
In vivo CRISPR-Cas9 knockout screening using quantitative PCR identifies thymosin beta-4 X-linked that promotes diffuse-type gastric cancer metastasis., PMID:34081824
In silico transcriptomic mapping of integrins and immune activation in Basal-like and HER2+ breast cancer., PMID:33469836
Transcriptome of nasopharyngeal samples from COVID-19 patients and a comparative analysis with other SARS-CoV-2 infection models reveal disparate host responses against SARS-CoV-2., PMID:33413422
Comprehensive analysis of ALK, ROS1 and RET rearrangements in locally advanced rectal cancer., PMID:33168793
Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves' ophthalmopathy., PMID:33153489
Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf., PMID:32999280
Oncogenic function of TRIM2 in pancreatic cancer by activating ROS-related NRF2/ITGB7/FAK axis., PMID:32929153
Functional Molecular Network Analysis Enables Prediction of Response to Vedolizumab Therapy in Anti-TNF Refractory IBD Patients., PMID:32776006
The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes., PMID:32616651
Differentially Expressed Genes of Natural Killer Cells Can Distinguish Rheumatoid Arthritis Patients from Healthy Controls., PMID:32365786
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines., PMID:31819523
Abnormal Peyer patch development and B-cell gut homing drive IgA deficiency in Kabuki syndrome., PMID:31816409
Genome-Wide Association Study Confirming a Strong Effect of HLA and Identifying Variants in CSAD/lnc-ITGB7-1 on Chromosome 12q13.13 Associated With Susceptibility to Fulminant Type 1 Diabetes., PMID:30552108
Epstein-Barr Virus Induces Expression of the LPAM-1 Integrin in B Cells In Vitro and In Vivo., PMID:30541846
Morphological, immunophenotypic, and genetic features of chronic lymphocytic leukemia with trisomy 12: a comprehensive review., PMID:29748447
Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation., PMID:29695247
The effects of kisspeptin-10 on serum metabolism and myocardium in rats., PMID:28692647
Screening and functional analysis of differentially expressed genes in chronic glomerulonephritis by whole genome microarray., PMID:27222482
The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival., PMID:26728187
Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach., PMID:26654242
For research use only. Not for human or drug use.
