Catalog No.
YHD38801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg253-Gln491
Predicted molecular weight
42.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20309
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Muscarinic acetylcholine receptor M3, CHRM3
Exploration of Asparagus racemosus Willd for Alzheimer's Disease Through Integrated Metabolomics and Network Pharmacology Analyses Targeting BACE1 Protein., PMID:40483633
Transcriptional and functional profiles of muscarinic receptor-expressing neurons in primate lateral prefrontal and anterior cingulate cortices., PMID:40475401
Impact of temporal food restriction on sleep behavior and physiology of redheaded bunting., PMID:40389169
Attenuation of intestinal peristalsis with age is attributed to decreased sensitivity of receptors in the enteric nervous system., PMID:40146304
Epitomic profiling and functional characteristics of pemphigus vulgaris autoantibody binding to keratinocyte M3 muscarinic acetylcholine receptor., PMID:40120680
Vagal pathway activation links chronic stress to decline in intestinal stem cell function., PMID:40120585
Material basis and mechanism of Ephedra sinica in interfering with wind-chill cold., PMID:40058103
Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches., PMID:39938415
Muscarinic acetylcholine receptor 3 localized to primary endothelial cilia regulates blood pressure and cognition., PMID:39885271
Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights., PMID:39809229
Comprehensive Gene Expression Analysis Using Human Induced Pluripotent Stem Cells Derived from Patients with Sleep Bruxism: A Preliminary In Vitro Study., PMID:39684851
Long term Coptidis Rhizoma intake induce gastrointestinal emptying inhibition and colon barrier weaken via bitter taste receptors activation in mice., PMID:39631296
Bone marrow mesenchymal stem cell-derived exosomal miR-181a-5p promotes M2 macrophage polarization to alleviate acute pancreatitis through ZEB2-mediated RACK1 ubiquitination., PMID:39614664
The complete mitochondrial DNA of the carnivorous sponge Lycopodina hypogea is putatively complemented by microDNAs., PMID:39559335
Acute Hypobaric Hypoxia Causes Alterations in Acetylcholine-Mediated Signaling Through Varying Expression of Muscarinic Receptors in the Prefrontal Cortex and Cerebellum of Rats' Brain., PMID:39379070
Darifenacin: a promising chitinase 3-like 1 inhibitor to tackle drug resistance in pancreatic ductal adenocarcinoma., PMID:39225813
Protective role of M3 muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury., PMID:39172154
CHRM3 (rs2165870) gene polymorphism is related to postoperative vomiting in female patients undergoing laparoscopic surgery. Prospective observational study., PMID:39163289
Tongxieyaofang Decotion Alleviates IBS by Modulating CHRM3 and Gut Barrier., PMID:39081703
[Retracted] MicroRNA‑30e inhibits adhesion, migration, invasion and cell cycle progression of prostate cancer cells via inhibition of the activation of the MAPK signaling pathway by downregulating CHRM3., PMID:39027991
PM10 exposure induces bronchial hyperresponsiveness by upreguating acetylcholine muscarinic 3 receptor., PMID:39019094
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families., PMID:38641412
Characterization of age-associated gene expression changes in mouse sweat glands., PMID:38637019
Effects of DDT and DDE on placental cholinergic receptors., PMID:38615785
Targeting Farnesoid X Receptor in Tumor and the Tumor Microenvironment: Implication for Therapy., PMID:38203175
Role of ecto-5'-nucleotidase in bladder function., PMID:38198186
Transcriptome analysis of Schizothorax oconnori (Cypriniformes: Cyprinidae) oocytes: The role of K+ in promoting yolk globule fusion and regulating oocyte maturation., PMID:38047980
Associations of genetic variations in the M3 receptor with salt sensitivity, longitudinal changes in blood pressure and the incidence of hypertension in Chinese adults., PMID:38010846
Itga8-Cre-mediated deletion of YAP and TAZ impairs bladder contractility with minimal inflammation and chondrogenic differentiation., PMID:37927241
CHRM3 is a novel prognostic factor of poor prognosis and promotes glioblastoma progression via activation of oncogenic invasive growth factors., PMID:37744266
Severity of neurological Long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors., PMID:37689093
Co-expression module analysis reveals high expression homogeneity for both coding and non-coding genes in sepsis., PMID:37488493
A Study on the Effects of Muscarinic and Serotonergic Regulation by Bojanggunbi-tang on the Pacemaker Potential of the Interstitial Cells of Cajal in the Murine Small Intestine., PMID:37484801
High-Throughput Sequencing Data Reveal an Antiangiogenic Role of HNF4A-Mediated CACNA1A/VEGFA Axis in Proliferative Diabetic Retinopathy., PMID:37342032
Use of whole genome sequencing to determine the genetic basis of visceral myopathies including Prune Belly syndrome., PMID:37288276
Identification of novel molecular subtypes and a signature to predict prognosis and therapeutic response based on cuproptosis-related genes in prostate cancer., PMID:37205181
Plant molecular farming-derived epidermal growth factor revolutionizes hydrogels for improving glandular epithelial organoid biofabrication., PMID:36966988
CHRM3-Associated miRNAs May Play a Role in Bile Acid-Induced Proliferation of H508 Colon Cancer Cells., PMID:36919835
MiR-15b-5p inhibits castration-resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM3., PMID:36754848
Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease-related Sleep Disturbances., PMID:36475335
Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles., PMID:36468138
Study on Medication Rules of Traditional Chinese Medicine in Treating Constipation through Data Mining and Network Pharmacology., PMID:36267846
Dysregulation of Circulatory Levels of lncRNAs in Parkinson's Disease., PMID:36264433
Exploring the Mechanism of Wenshen Huatan Quyu Decotion for PCOS Based on Network Pharmacology and Molecular Docking Verification., PMID:36071733
Identification of ceRNA regulatory network in acute pancreatitis and acute recurrent pancreatitis., PMID:36052691
Exploring the Target and Mechanism of Radix Paeoniae Alba on Sjogren's Syndrome., PMID:36017844
Examining SNP-SNP interactions and risk of clinical outcomes in colorectal cancer using multifactor dimensionality reduction based methods., PMID:35991579
A Genomic Instability-Associated Prognostic Signature for Glioblastoma Patients., PMID:35977679
Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands., PMID:35967390
Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells., PMID:35955642
For research use only. Not for human or drug use.
