Catalog No.
YHD02301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp249
Predicted molecular weight
30.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13984
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
General transcription factor IIF subunit 2, General transcription factor IIF 30 kDa subunit, Transcription initiation factor IIF subunit beta, TFIIF-beta, Transcription initiation factor RAP30, GTF2F2, RAP30
Single-cell RNA sequencing reveals the role of GTF2F2 in ovarian cancer oncogenesis and progression., PMID:40442848
Genomic evidence for demographic fluctuations, genetic burdens and adaptive divergence in fourfinger threadfin Eleutheronema rhadinum., PMID:40027332
Mechanism of mammalian transcriptional repression by noncoding RNA., PMID:39762629
Role of interferon alpha-inducible protein 6 in modulating the proliferation, apoptosis and senescence of oesophageal squamous cell carcinoma cells., PMID:37661181
Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III., PMID:37230389
Contribution of labor related gene subtype classification on heterogeneity of polycystic ovary syndrome., PMID:36857354
General Transcription Factor IIF Polypeptide 2: A Novel Therapeutic Target for Depression Identified Using an Integrated Bioinformatic Analysis., PMID:35711908
LINE1 are spliced in non-canonical transcript variants to regulate T cell quiescence and exhaustion., PMID:35039641
Integrating microRNA expression, miRNA-mRNA regulation network and signal pathway: a novel strategy for lung cancer biomarker discovery., PMID:34754623
Single-molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes., PMID:34384542
Shared Blood Transcriptomic Signatures between Alzheimer's Disease and Diabetes Mellitus., PMID:33406707
Dynamics of the RNA polymerase I TFIIF/TFIIE-like subcomplex: a mini-review., PMID:32915199
Nucleotide Loading Modes of Human RNA Polymerase II as Deciphered by Molecular Simulations., PMID:32906795
Transcriptomic analyses suggest that mucopolysaccharidosis patients may be less susceptible to COVID-19., PMID:32880920
In vitro reconstitution of yeast RNA polymerase II transcription initiation with high efficiency., PMID:30905750
Comparative proteomic analysis of high- and low-fertile buffalo bull spermatozoa for identification of fertility-associated proteins., PMID:30820981
Deriving a sub-nanomolar affinity peptide from TAP to enable smFRET analysis of RNA polymerase II complexes., PMID:30742995
PIBIDS syndrome in two Brazilian siblings., PMID:30580289
MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis., PMID:30415952
The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex., PMID:30398641
Molecular mechanism of promoter opening by RNA polymerase III., PMID:29345638
Structural basis of RNA polymerase III transcription initiation., PMID:29345637
Hypoxic regulation of MYBL1, MEST, TCF3, TCF8, GTF2B, GTF2F2 and SNAI2 genes expression in U87 glioma cells upon IRE1 inhibition., PMID:29235836
Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators., PMID:29225078
An RNA polymerase II-associated TFIIF-like complex is indispensable for SL RNA gene transcription in Trypanosoma brucei., PMID:29186511
TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning., PMID:29106413
The mutation nrpb1-A325V in the largest subunit of RNA polymerase II suppresses compromised growth of Arabidopsis plants deficient in a function of the general transcription factor IIF., PMID:27862530
Gdown1 Associates Efficiently with RNA Polymerase II after Promoter Clearance and Displaces TFIIF during Transcript Elongation., PMID:27716820
Specialization versus conservation: How Pol I and Pol III use the conserved architecture of the pre-initiation complex for specialized transcription., PMID:27327079
Super elongation complex contains a TFIIF-related subcomplex., PMID:27223670
Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity., PMID:27112574
Expression of proliferation related transcription factor genes in U87 glioma cells with IRE1 knockdown: upon glucose and glutamine deprivation., PMID:29537195
xiNET: cross-link network maps with residue resolution., PMID:25648531
SILAC-based proteomic profiling of the human MDA-MB-231 metastatic breast cancer cell line in response to the two antitumoral lactoferrin isoforms: the secreted lactoferrin and the intracellular delta-lactoferrin., PMID:25116916
UVB induces a genome-wide acting negative regulatory mechanism that operates at the level of transcription initiation in human cells., PMID:25058334
Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters., PMID:25023704
Conserved architecture of the core RNA polymerase II initiation complex., PMID:25007739
Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms., PMID:24733897
Regulation of RNA polymerase II termination by phosphorylation of Gdown1., PMID:24634214
Functional interactions of the RNA polymerase II-interacting proteins Gdown1 and TFIIF., PMID:24596085
Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics., PMID:24550488
RNA polymerase I structure and transcription regulation., PMID:24153182
Transcriptional coactivator CIITA, a functional homolog of TAF1, has kinase activity., PMID:24036077
A role for CF1A 3' end processing complex in promoter-associated transcription., PMID:23966880
RNA polymerase III-specific general transcription factor IIIC contains a heterodimer resembling TFIIF Rap30/Rap74., PMID:23921640
Hybrid electron microscopy-FRET imaging localizes the dynamical C-terminus of Tfg2 in RNA polymerase II-TFIIF with nanometer precision., PMID:23732819
Variants in the 3' UTR of general Transcription factor IIF, polypeptide 2 affect female calving efficiency in Japanese Black cattle., PMID:23663537
Structural visualization of key steps in human transcription initiation., PMID:23446344
The non-coding B2 RNA binds to the DNA cleft and active-site region of RNA polymerase II., PMID:23416138
RNA polymerase II mutations conferring defects in poly(A) site cleavage and termination in Saccharomyces cerevisiae., PMID:23390594
For research use only. Not for human or drug use.
