Catalog No.
YHD00401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn27-Glu330
Predicted molecular weight
35.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13716
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Delta-aminolevulinic acid dehydratase, ALADH, 4.2.1.24, Porphobilinogen synthase, ALAD
Global Variation in Lipoprotein(a) Levels Among Patients With Coronary Heart Disease: Insights From the INTERASPIRE Study and Implications for Emerging Lp(a)-Lowering Therapies., PMID:40436467
Assessment of the participation of sulfhydryl proteins in the glutathione peroxidase mimicry of diphenyl diselenide in the presence of thiol alkylating agent., PMID:40394079
Link N Directly Targets IL-1β to Suppress Inflammation and Regulate Sensory Pain in Intervertebral Disc Degeneration., PMID:40305345
Emergence of a senescent and inflammatory pulmonary CD4+ T cell population prior to lung allograft failure., PMID:40117366
Advances in the Regulation of Periostin for Osteoarthritic Cartilage Repair Applications., PMID:39595645
Short Link N Modulates Inflammasome Activity in Intervertebral Discs Through Interaction with CD14., PMID:39456246
Integrative multi-omics summary-based mendelian randomization identifies key oxidative stress-related genes as therapeutic targets for atrial fibrillation and flutter., PMID:39359474
Systematic proteome-wide Mendelian randomization using the human plasma proteome to identify therapeutic targets for lung adenocarcinoma., PMID:38576019
More indications for redox-sensitive cysteine residues of the Arabidopsis 5-aminolevulinate dehydratase., PMID:38317833
Identification of common genes and pathways underlying imatinib and nilotinib treatment in CML: a Bioinformatics Study., PMID:38117080
Sub-lethal impacts of lead poisoning on blood biochemistry, immune function and delta-aminolevulinic acid dehydratase (δ-ALAD) activity in Cape (Gyps coprotheres) and white-backed (G. africanus) Vulture chicks., PMID:38104912
[Characteristics of δ-Aminolevulinic Acid Dehydratase of the Cold-Water Sponge Halisarca dujardinii]., PMID:38062963
Heme Biosynthesis is Crucial for Cell Survival and Mitochondrial OXPHOS after X Irradiation., PMID:37988802
Inhibition of ALA dehydratase activity in heme biosynthesis reduces cytoglobin expression which is related to the proliferation and viability of keloid fibroblasts., PMID:37970551
Expression deregulation of genes related to DNA repair and lead toxicity in occupationally exposed industrial workers., PMID:37804366
NTRC and TRX-f Coordinately Affect the Levels of Enzymes of Chlorophyll Biosynthesis in a Light-Dependent Manner., PMID:37371140
Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis of the Blood Proteome., PMID:37212950
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review., PMID:36642627
ALAD and APOE polymorphisms are associated with lead and mercury levels in Italian pregnant women and their newborns with adequate nutritional status of zinc and selenium., PMID:36621546
Quantitative relationships between ingested and intestinal flows of linoleic and alpha-linolenic acids, body weight and milk performance in mid-lactation dairy cows., PMID:36327797
Role of Ape1 in Impaired DNA Repair Capacity in Battery Recycling Plant Workers Exposed to Lead., PMID:35805621
Interferon-stimulated and metallothionein-expressing macrophages are associated with acute and chronic allograft dysfunction after lung transplantation., PMID:35691795
The CaALAD Gene From Pepper (Capsicum annuum L.) Confers Chilling Stress Tolerance in Transgenic Arabidopsis Plants., PMID:35574110
Isolation and allergenicity evaluation of glycated α-lactalbumin digestive products and identification of allergenic peptides., PMID:35567971
Modification by genetic polymorphism of lead-induced IQ alteration: a systematic review., PMID:35386084
Analysis of corticosteroid and antiepileptic drug treatment effects on heme biosynthesis mRNA expression in lower-grade gliomas: Potential implications for 5-ALA metabolization., PMID:35149260
Silencing of δ-aminolevulinic acid dehydratase via virus induced gene silencing promotes callose deposition in plant phloem., PMID:34994280
Proteomics discovery of protein biomarkers linked to yak meat tenderness as determined by label-free mass spectrometry., PMID:34882917
The effect of camelina oil on vascular function in essential hypertensive patients with metabolic syndrome: a randomized, placebo-controlled, double-blind study., PMID:34791007
Ameliorative effects of nutritional minerals on lead-induced hematological alterations in male Wistar albino rats., PMID:34334063
Genetic susceptibility of δ-ALAD associated with lead (Pb) intoxication: sources of exposure, preventive measures, and treatment interventions., PMID:34244947
Analysis of rare coding variants in 200,000 exome-sequenced subjects reveals novel genetic risk factors for type 2 diabetes., PMID:34216101
Downregulating of hemB via synthetic antisense RNAs for improving 5-aminolevulinic acid production in Escherichia coli., PMID:33968574
Association between the renin-angiotensin system and chronic lung allograft dysfunction., PMID:33863738
Exploring human porphobilinogen synthase metalloprotein by quantum biochemistry and evolutionary methods., PMID:33791795
Genome-Wide Analysis of Differentially Expressed miRNAs and Their Associated Regulatory Networks in Lenses Deficient for the Congenital Cataract-Linked Tudor Domain Containing Protein TDRD7., PMID:33665188
Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase., PMID:33298951
Influence of VDR and HFE polymorphisms on blood lead levels of occupationally exposed workers., PMID:33233953
Metabolic syndrome in rheumatoid arthritis patients: Relationship among its clinical components., PMID:33231330
Wide-open conformation of UDP-MurNc-tripeptide ligase revealed by the substrate-free structure of MurE from Acinetobacter baumannii., PMID:33230844
An eleven metabolic gene signature-based prognostic model for clear cell renal cell carcinoma., PMID:33221754
5-Aminolevulinate dehydratase porphyria: Update on hepatic 5-aminolevulinic acid synthase induction and long-term response to hemin., PMID:33199206
Effect of iron and folate supplementation on Pb levels in pregnant anemic women: a prospective study., PMID:32954897
Lead exposure induces metabolic reprogramming in rat models., PMID:32949623
TCGA mRNA Expression Analysis of the Heme Biosynthesis Pathway in Diffusely Infiltrating Gliomas: A Comparison of Typically 5-ALA Fluorescent and Non-Fluorescent Gliomas., PMID:32722247
Effect of lead exposure and nutritional iron-deficiency on immune response: A vaccine challenge study in rats., PMID:32574507
The Se…S/N interactions as a possible mechanism of δ-aminolevulinic acid dehydratase enzyme inhibition by organoselenium compounds: A computational study., PMID:32572387
Blood lead level (BLL), δ-aminolevulinic acid dehydratase activity (ALAD), hemoglobin (Hb) and hematocrit (hct) in primary school-children and adult residents living in smelter rural areas in Kosovo., PMID:32567994
Leukocyte apoptosis, TNF-α concentration and oxidative damage in lead-exposed workers., PMID:32004562
Risk assessment of heavy metal toxicity by sensitive biomarker δ-aminolevulinic acid dehydratase (ALA-D) for onion plants cultivated in polluted areas in Kosovo., PMID:32003294
For research use only. Not for human or drug use.
