Catalog No.
YHC32801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Phe380
Predicted molecular weight
42.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08319
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
All-trans-retinol dehydrogenase [NAD(+)] ADH4, 1.1.1.105, Alcohol dehydrogenase 2, Alcohol dehydrogenase 4, Alcohol dehydrogenase class II pi chain, ADH4, ADH2
Exploring causal plasma protein level ratios and potential drug targets for depression: A proteomics Mendelian randomization study., PMID:40499826
Impact of DNA methylation on digestive and metabolic gene expression in red pandas (Ailurus fulgens) during the transition from milk to bamboo diet., PMID:40275147
Investigation of mitochondrial DNA methylation-related prognostic biomarkers in hepatocellular carcinoma using The Cancer Genome Atlas (TCGA) database., PMID:40224972
Integrative multi-omics analysis reveals molecular signatures of central obesity in children., PMID:40044886
Finding Potential Drug Targets for Pre-Eclampsia Using Mendelian Randomisation and Colocalisation Analysis., PMID:40028697
Characterization of human alcohol dehydrogenase 4 and aldehyde dehydrogenase 2 as enzymes involved in the formation of 5-carboxylpirfenidone, a major metabolite of pirfenidone., PMID:39884816
[Analysis of genetic association between exon polymorphisms of ADH4 and ADH7 and risky drinking behavior of alcoholic liver disease]., PMID:39710484
TSA attenuates the progression of c-Myc-driven hepatocarcinogenesis by pAKT-ADH4 pathway., PMID:39187747
ADH4-a potential prognostic marker for hepatocellular carcinoma with possible immune-related implications., PMID:39090641
Proteomics profiling and association with cardiorenal complications in type 2 diabetes subtypes in Asian population., PMID:39059739
Global Gene Expression Profiling and Bioinformatics Analysis Reveal Downregulated Biomarkers as Potential Indicators for Hepatocellular Carcinoma., PMID:38911766
Analysis of alcohol-metabolizing enzymes genetic variants and RAR/RXR expression in patients diagnosed with fetal alcohol syndrome: a case-control study., PMID:38886650
Identification of metabolism-related key genes as potential biomarkers for pathogenesis of immune thrombocytopenia., PMID:38641637
Proteomic and Metabolomic Signatures of Diet Quality in Young Adults., PMID:38337712
A novel metabolism-related gene signature in patients with hepatocellular carcinoma., PMID:38025761
Comparative Analysis of Different Proteins and Metabolites in the Liver and Ovary of Local Breeds of Chicken and Commercial Chickens in the Later Laying Period., PMID:37762699
An inflammation-associated ferroptosis signature optimizes the diagnosis, prognosis evaluation and immunotherapy options in hepatocellular carcinoma., PMID:37248957
ACE2 negatively regulates the Warburg effect and suppresses hepatocellular carcinoma progression via reducing ROS-HIF1α activity., PMID:37215979
Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses., PMID:37033211
Data-independent acquisition proteomics reveals circulating biomarkers of coronary chronic total occlusion in humans., PMID:36561774
Novel Insights into MEG3/miR664a-3p/ADH4 Axis and Its Possible Role in Hepatocellular Carcinoma from an in Silico Perspective., PMID:36553522
Screening for Lipid-Metabolism-Related Genes and Identifying the Diagnostic Potential of ANGPTL6 for HBV-Related Early-Stage Hepatocellular Carcinoma., PMID:36421714
Alcohol dehydrogenase 4 is a TP53-associated gene signature for the prediction of prognosis in hepatocellular carcinoma., PMID:36419756
The prognostic role of fatty acid metabolism-related genes in patients with gastric cancer., PMID:36388036
Identification and validation of a tyrosine metabolism-related prognostic prediction model and characterization of the tumor microenvironment infiltration in hepatocellular carcinoma., PMID:36341373
Distinctive Metabolism-Associated Gene Clusters That Are Also Prognostic in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma., PMID:36199423
miR-29c-3p promotes alcohol dehydrogenase gene cluster expression by activating an ADH6 enhancer., PMID:35868429
No significant association between SNPs in the CLOCK and ADH4 genes and susceptibility to cluster headaches: A systematic review and meta-analysis., PMID:35437765
Drug metabolism-related eight-gene signature can predict the prognosis of gastric adenocarcinoma., PMID:34773716
Multi-omics integration reveals the hepatoprotective mechanisms of ursolic acid intake against chronic alcohol consumption., PMID:34215920
A stemness-based eleven-gene signature correlates with the clinical outcome of hepatocellular carcinoma., PMID:34147074
Identification and validation of ADME genes as prognosis and therapy markers for hepatocellular carcinoma patients., PMID:33988674
A novel mechanism underlying alcohol dehydrogenase expression: hsa-miR-148a-3p promotes ADH4 expression via an AGO1-dependent manner in control and ethanol-exposed hepatic cells., PMID:33556337
Adh4, an alcohol dehydrogenase controls alcohol formation within bacterial microcompartments in the acetogenic bacterium Acetobacterium woodii., PMID:33283462
Evaluation of Anti-proliferative Effects of Barringtonia racemosa and Gallic Acid on Caco-2 Cells., PMID:32561807
Production of Methionol from 3-Methylthiopropionaldehyde by Catalysis of the Yeast Alcohol Dehydrogenase Adh4p., PMID:32233408
Candidate genes for predicting the survival of patients with gastric cancer: a study based on The Cancer Genome Atlas (TCGA) database., PMID:35117619
No genetic evidence for involvement of alcohol dehydrogenase genes in risk for Parkinson's disease., PMID:31806158
Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population., PMID:31768945
Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes., PMID:31682009
Alcohol dehydrogenases from Proteus mirabilis contribute to alcoholic flavor., PMID:30761541
Acid stress induces cross-protection for cadmium tolerance of multi-stress-tolerant Pichia kudriavzevii by regulating cadmium transport and antioxidant defense system., PMID:30513442
Modeling of Human Hepatic and Gastrointestinal Ethanol Metabolism with Kinetic-Mechanism-Based Full-Rate Equations of the Component Alcohol Dehydrogenase Isozymes and Allozymes., PMID:29847918
Performance of Homologous and Heterologous Prime-Boost Immunization Regimens of Recombinant Adenovirus and Modified Vaccinia Virus Ankara Expressing an Ag85B-TB10.4 Fusion Protein against Mycobacterium tuberculosis., PMID:29847865
Distinct Prognostic Values of Alcohol Dehydrogenase Family Members for Non-Small Cell Lung Cancer., PMID:29808834
Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis., PMID:29718361
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells., PMID:29323295
Genetic association of HCRTR2, ADH4 and CLOCK genes with cluster headache: a Chinese population-based case-control study., PMID:29318394
The potential of the newly isolated thermotolerant yeast Pichia kudriavzevii RZ8-1 for high-temperature ethanol production., PMID:29154013
First description and evaluation of SNPs in the ADH and ALDH genes in a population of alcoholics in Central-West Brazil., PMID:29084628
For research use only. Not for human or drug use.
