Catalog No.
YHC25501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala135-Arg498
Predicted molecular weight
43.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07357
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Complement component C8 alpha chain, Complement component 8 subunit alpha, C8A
LC-MS/MS proteomics identifies plasma proteins related to cognition over 9-year follow-up., PMID:40469059
Dissecting oxidative folding of conotoxins using 3D structures of cysteine mutants predicted by AlphaFold 3: A case study of α-conotoxin RgIA, χ-conotoxin CMrVIA and ω-conotoxin MVIIA-Gly., PMID:40345559
Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring., PMID:40281624
Protective Vaccination of Mice Against Blood-Stage Malaria Impacts Hepatic Expression of Genes Encoding Acute-Phase Proteins and IL-6 Family Members., PMID:40243929
Genome-wide mapping of complement system proteins for islet autoimmunity in the DAISY and TEDDY children., PMID:39989961
Hepatocyte nuclear factor 4α is a critical factor for the production of complement components in the liver., PMID:39285151
Mass Spectrometry Proteomics Characterization of Plasma Biomarkers for Colorectal Cancer Associated With Inflammation., PMID:38911905
Comprehensive Urinary Proteome Profiling Analysis Identifies Diagnosis and Relapse Surveillance Biomarkers for Bladder Cancer., PMID:38787199
Effective xanthine oxidase inhibitor urate lowering therapy in gout is linked to an emergent serum protein interactome of complement activation and inflammation modulators., PMID:38766125
Sustained xanthine oxidase inhibitor treat to target urate lowering therapy rewires a tight inflammation serum protein interactome., PMID:38260556
Comparative transcriptome analysis reveals potential regulatory mechanisms of genes and immune pathways following Vibrio harveyi infection in red drum (Sciaenops ocellatus)., PMID:38242261
Evaluation of the significance of complement-related genes mutations in atypical postinfectious glomerulonephritis: a pilot study., PMID:37845399
Proteomic landscape of extracellular vesicles in human retinal cells infected with Staphylococcus aureus and Pseudomonas aeruginosa: Role in endophthalmitis., PMID:37075825
Urinary complement proteins in IgA nephropathy progression from a relative quantitative proteomic analysis., PMID:37065697
A Systematic Investigation of Complement and Coagulation-Related Protein in Autism Spectrum Disorder Using Multiple Reaction Monitoring Technology., PMID:37031449
Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock., PMID:36459524
Significance of urine complement proteins in monitoring lupus activity., PMID:36420131
Complement C5 is a novel biomarker for liver metastasis of colorectal cancer., PMID:36388659
The adverse inflammatory response of tobacco smoking in COVID-19 patients: biomarkers from proteomics and metabolomics., PMID:35772384
Novel plasma glycoprotein biomarkers predict progression-free survival in surgically resected clear cell renal cell carcinoma., PMID:35148948
Metabolomic and proteomic characterization of sng and pain phenotypes in fibromyalgia., PMID:34608709
Mass Spectrometry-Based Proteomic Discovery of Prognostic Biomarkers in Adrenal Cortical Carcinoma., PMID:34359790
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma., PMID:34050187
Fish complement C8 evolution, functional network analyses, and the theoretical interaction between C8 alpha chain and CD59., PMID:33160183
A Point Mutation Creating a 3' Splice Site in C8A Is a Predominant Cause of C8α-γ Deficiency in African Americans., PMID:32769119
Optimized Hepatitis C Virus (HCV) E2 Glycoproteins and their Immunogenicity in Combination with MVA-HCV., PMID:32764419
Bioinformatics analysis of key biomarkers and potential molecular mechanisms in hepatocellular carcinoma induced by hepatitis B virus., PMID:32443377
Improved milbemycin production by engineering two Cytochromes P450 in Streptomyces bingchenggensis., PMID:32043186
Glycopatterns and Glycoproteins Changes in MCN and SCN: A Prospective Cohort Study., PMID:31467879
Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress., PMID:30635638
Identification of Prognostic and Susceptibility Markers in Chronic Myeloid Leukemia Using Next Generation Sequencing., PMID:29983511
Intranasal monkeypox marmoset model: Prophylactic antibody treatment provides benefit against severe monkeypox virus disease., PMID:29927927
Multi-lectin Affinity Chromatography and Quantitative Proteomic Analysis Reveal Differential Glycoform Levels between Prostate Cancer and Benign Prostatic Hyperplasia Sera., PMID:29695737
Sparking Fire Under the Skin? Answers From the Association of Complement Genes With Pemphigus Foliaceus., PMID:29686679
Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans., PMID:28594911
Topical Ophthalmic Formulation of Trichostatin A and SurR9-C84A for Quick Recovery Post-alkali Burn of Corneal Haze., PMID:28529481
Tissue toxicokinetics of perfluoro compounds with single and chronic low doses in male rats., PMID:28496036
Inflammation Thread Runs across Medical Laboratory Specialities., PMID:27493451
A Proteomic Investigation of Hepatic Resistance to Ascaris in a Murine Model., PMID:27490109
The mutational profile and infiltration pattern of murine MLH1-/- tumors: concurrences, disparities and cell line establishment for functional analysis., PMID:27447752
Proteomic analysis of preovulatory follicular fluid reveals differentially abundant proteins in less fertile dairy cows., PMID:27003612
The complement system of elasmobranches revealed by liver transcriptome analysis of a hammerhead shark, Sphyrna zygaena., PMID:26987526
Identification of Circulating Biomarker Candidates for Hepatocellular Carcinoma (HCC): An Integrated Prioritization Approach., PMID:26414287
Inactive C8A‑humanin analog is as stable as a potent S14G‑humanin analog., PMID:24247787
Myelin basic protein undergoes a broader range of modifications in mammals than in lower vertebrates., PMID:22420465
The three-way relationship of polymorphisms of porcine genes encoding terminal complement components, their differential expression, and health-related phenotypes., PMID:21645298
Genetic variability of the coding region for the prion protein gene (PRNP) in gayal (Bos frontalis)., PMID:21633886
Biophysical analysis of influenza A virus RNA promoter at physiological temperatures., PMID:21555520
Laser spectroscopy of conformationally constrained alpha/beta-peptides: Ac-ACPC-Phe-NHMe and Ac-Phe-ACPC-NHMe., PMID:20039717
Selective removal of individual disulfide bonds within a potato type II serine proteinase inhibitor from Nicotiana alata reveals differential stabilization of the reactive-site loop., PMID:19925809
For research use only. Not for human or drug use.
