Catalog No.
YHC16801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln23-Asn166
Predicted molecular weight
18.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05451
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lithostathine-1-alpha, Islet cells regeneration factor, ICRF, Islet of Langerhans regenerating protein, REG, Pancreatic stone protein, PSP, Pancreatic thread protein, PTP, Regenerating islet-derived protein 1-alpha, REG-1-alpha, Regenerating protein I alpha, REG1A, PSPS, PSPS1, REG
Serum regenerative islet-derived protein 1α: a novel and sensitive biomarker for endoscopic disease activity in ulcerative colitis., PMID:40289639
An Integrative Analysis of Transcriptome Combined with Machine Learning and Single-Cell RNA-Seq for the Common Biomarkers in Crohn's Disease and Kidney Stone Disease., PMID:40242727
Identification of Cardiometabolic Protein Biomarkers for Acute Myocardial Infarction Using Olink Proteomics., PMID:40013238
Pancreatic Stone Protein as Sepsis Biomarker in Patients Requiring Mechanical Circulatory Support: A Pilot Observational Study., PMID:39971654
Gene expression regulation and polyadenylation in ulcerative colitis via long-chain RNA sequencing., PMID:39955510
Association between elevated serum REG Iα levels and eGFR decline in patients with chronic kidney disease: a cross-sectional study in eastern China., PMID:39947821
Causal associations between circulating protein ratios and drug resistance in papillary thyroid cancer: a Mendelian randomization study., PMID:39754686
Multi-omic biomarker panel in pancreatic cyst fluid and serum predicts patients at a high risk of pancreatic cancer development., PMID:39747972
Bioinformatics analysis of colorectal cancer transcriptomic data reveals novel prognostic signature and potential biomarker genes., PMID:39644158
Systematic literature review on early clinical evidence for immune-resolution therapies and potential benefits to patients and healthcare providers., PMID:39483464
Circulating Factors as Potential Biomarkers of Cardiovascular Damage Progression Associated with Type 2 Diabetes., PMID:39449501
Prognostic and diagnostic utility of pancreatic stone protein in pediatric sepsis and mortality., PMID:39295616
Urinary biomarkers analysis as a diagnostic tool for early detection of pancreatic adenocarcinoma: Molecular quantification approach., PMID:39159599
Pancreatic Stone Protein in the Diagnosis of Sepsis in Children Admitted to High-Dependency Care: A Single-Center Prospective Cohort Study., PMID:39023339
Serum biomarkers REG1A and REG3A combined with the traditional CEA represent a novel nomogram for the screening and risk stratification of colorectal cancer., PMID:38965192
Identification of biomarkers and potential therapeutic targets for pancreatic cancer by proteomic analysis in two prospective cohorts., PMID:38754433
Diagnostic accuracy of pancreatic stone protein in patients with sepsis: a systematic review and meta-analysis., PMID:38711008
Serial monitoring of pancreatic stone protein for the detection of sepsis in intensive care unit patients with complicated abdominal surgery: A prospective, longitudinal cohort study., PMID:38471247
E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner., PMID:38414029
Linking gene expression to clinical outcomes in pediatric Crohn's disease using machine learning., PMID:38302662
Effect of Metformin on Plasma and Cerebrospinal Fluid Biomarkers in Non-Diabetic Older Adults with Mild Cognitive Impairment Related to Alzheimer's Disease., PMID:38160357
REG1A protects retinal photoreceptors from blue light damage., PMID:37531162
RNA-Seq Analysis of Clinical Samples from TCGA Reveal Molecular Signatures for Ovarian Cancer., PMID:36797673
Integrated multiple microarray studies by robust rank aggregation to identify immune-associated biomarkers in Crohn's disease based on three machine learning methods., PMID:36792688
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach., PMID:36572850
Identification of regenerating island-derived protein 3E in dogs., PMID:36387376
Gene signature and connectivity mapping to assist with drug prediction for pancreatic ductal adenocarcinoma., PMID:36116415
Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation., PMID:36002022
REG1A and RUNX3 Are Potential Biomarkers for Predicting the Risk of Diabetic Kidney Disease., PMID:35937821
Pancreatic Stone Protein as a Biomarker for Sepsis at the Emergency Department of a Large Tertiary Hospital., PMID:35631080
Correlation of REG1A, Claudin 7 and Ki67 expressions with tumor recurrence and prognostic factors in superficial urothelial urinary bladder carcinomas., PMID:35435371
Identification of diagnostic signatures in ulcerative colitis patients via bioinformatic analysis integrated with machine learning., PMID:34731452
Pancreatic stone protein for early mortality prediction in COVID-19 patients., PMID:34325711
The Potential Role of REG Family Proteins in Inflammatory and Inflammation-Associated Diseases of the Gastrointestinal Tract., PMID:34281249
Accuracy of pancreatic stone protein for the diagnosis of infection in hospitalized adults: a systematic review and individual patient level meta-analysis., PMID:34049579
Acute FPIES reactions are associated with an IL-17 inflammatory signature., PMID:33891982
Serial measurement of pancreatic stone protein for the early detection of sepsis in intensive care unit patients: a prospective multicentric study., PMID:33879189
Protective and anti-inflammatory role of REG1A in inflammatory bowel disease induced by JAK/STAT3 signaling axis., PMID:33513463
Re-expression of REG family and DUOXs genes in CRC organoids by co-culturing with CAFs., PMID:33483567
A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer: A case-control study., PMID:33301466
Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip., PMID:33074011
Serum REG Iα as a potential novel biomarker in cancer: An observational study., PMID:32957383
Carboxypeptidase A1 and regenerating islet-derived 1α as new markers for pancreatic acinar cell carcinoma., PMID:32702400
Expression of Pancreatic Stone Protein is Unaffected by Trauma and Subsequent Surgery in Burn Patients., PMID:32451625
Identification of key genes and pathways in gastric signet ring cell carcinoma based on transcriptome analysis., PMID:32149050
Urine E-cadherin: A Marker for Early Detection of Kidney Injury in Diabetic Patients., PMID:32121033
Pancreatic stone protein - sepsis and the riddles of the exocrine pancreas., PMID:32037128
Cell-Free DNA Methylation: The New Frontiers of Pancreatic Cancer Biomarkers' Discovery., PMID:31877923
Association of regenerating gene 1A single-nucleotide polymorphisms and nasopharyngeal carcinoma susceptibility in southern Chinese population., PMID:31541294
Wnt/β-catenin signaling as a useful therapeutic target in hepatoblastoma., PMID:31511432
For research use only. Not for human or drug use.
