Catalog No.
YHB99102
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp631-Gln866
Predicted molecular weight
28.90 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02671
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fibrinogen alpha chain, Fibrinopeptide A, Fibrinogen alpha chain, FGA
Proteomic Analysis of the Extracellular Matrix in the Porcine Adrenal Cortex., PMID:40493856
Neuroinflammation Markers in Tear Fluid of Mild Alzheimer's Disease., PMID:40471493
The factor V H1327R (rs1800595) polymorphism is associated with venous thromboembolic events: a case-control study in southern Iran., PMID:40464840
Bi-allelic variants in POPDC2 cause an autosomal recessive syndrome presenting with cardiac conduction defects and hypertrophic cardiomyopathy., PMID:40409267
Association of matrix metalloproteinase 7 and the alpha-chain of fibrinogen at baseline with response to methotrexate at 3 months in patients with early rheumatoid arthritis., PMID:40400044
FGA can be used as a promising therapeutic target in osteoarthritis., PMID:40394574
[Clinical characteristics and genotypes of patients with Congenital fibrinogen disorders]., PMID:40372216
HNF-1α promotes urethral fibrosis by up-regulating STAT3 transcriptional activity in mice hypospadias., PMID:40348066
Rare loss-of-function variants in HECTD2 and AKAP11 confer risk of bipolar disorder., PMID:40133559
Chronic sleep curtailment expediates brain aging by activating the complement and coagulation cascades in mice., PMID:40027811
[Molecular Pathogenic Mechanism Study of Two Cases of Inherited Dysfibrinogenemia]., PMID:40017205
Fibrinogen Alpha Chain as a Potential Serum Biomarker for Predicting Response to Cisplatin and Gemcitabine Doublet Chemotherapy in Lung Adenocarcinoma: Integrative Transcriptome and Proteome Analyses., PMID:39940778
Multiple metachronous foveolar-type gastric adenomas in a Helicobacter pylori-naïve patient with long-term use of a proton pump inhibitor: a case report., PMID:39939466
Global patterns of amyloid typing: results of a survey by the International Society of Amyloidosis (ISA)., PMID:39928315
Association of Fibrinogen Aα Thr312Ala (rs6050) Polymorphism with Venous Thrombosis and Chronic Thromboembolic Pulmonary Hypertension: A Meta-Analysis., PMID:39838925
Alternative Splicing Events and Differently Expressed Genes During Peak Mortality in Large Yellow Croaker (Larimichthys crocea) Infected with Scuticociliate., PMID:39833483
Fibrinogen genotypes and their impact on recurrence of venous thromboembolism and family history: A prospective population-based study., PMID:39828282
HN1 Functions in Protein Synthesis Regulation via mTOR-RPS6 Axis and Maintains Nucleolar Integrity., PMID:39805577
Unravelling the transcriptomic symphony of muscle ageing: key pathways and hub genes altered by ageing and caloric restriction in rat muscle revealed by RNA sequencing., PMID:39800693
Identifying the key role of mitochondrial respiration and lipid metabolism in regulating axillary osmidrosis through proteomics analysis., PMID:39673600
SARS-COV-2 ORF9b Dysregulate Fibrinogen and Albumin Genes in a Liver Cell Line., PMID:39582820
Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites., PMID:39580674
Proteomic study of cerebrospinal fluid in adult tethered cord syndrome: Chemical structure and function of apolipoprotein B., PMID:39547612
Proteomic identification of potential biomarkers for heat tolerance in Caracu beef cattle using high and low thermotolerant groups., PMID:39538142
Transcriptomic Analysis Reveals Dynamics of Gene Expression in Liver Tissue of Spotted Sea Bass Under Acute Thermal Stress., PMID:39432208
Clinical manifestations, diagnosis and treatment of hereditary fibrinogen Aα-chain renal amyloidosis: one case report and systematic review., PMID:39417966
Identification of FGG as a Biomarker in Early Gastric Cancer via Tissue Proteomics and Clinical Verification., PMID:39417528
Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid., PMID:39391051
Genomic and clinical landscape of metastatic hormone receptors-positive breast cancers carrying ESR1 alterations., PMID:39357123
Proteomic analysis of cerebrospinal fluid of amyotrophic lateral sclerosis patients in the presence of autologous bone marrow derived mesenchymal stem cells., PMID:39278909
FGA influences invasion and metastasis of hepatocellular carcinoma through the PI3K/AKT pathway., PMID:39227068
Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles., PMID:39226462
Regulation of fibrinogen synthesis., PMID:39216273
[Clinical phenotypes and genotypes of congenital fibrinogen disorder: an analysis of 16 children]., PMID:39148389
Identification of regulatory networks and crosstalk factors in brown adipose tissue and liver of a cold-exposed cardiometabolic mouse model., PMID:39143620
Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging., PMID:39140961
Congenital Hypodysfibrinogenemia due to γ326Cys→Tyr Mutation: Third Ever-Described Case Associated with Recurrent Venous Thrombosis and COVID Vaccine., PMID:39140696
Glycerophosphoinositol modulates FGA and NOTCH3 in exercise-induced muscle adaptation and colon cancer progression., PMID:39130639
Activated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation., PMID:39116293
Genomic profiling of lymph node and distant metastases from papillary and poorly differentiated thyroid carcinomas., PMID:39030377
Discovery of candidate biomarkers from plasma-derived extracellular vesicles of patients with cirrhosis and hepatocellular carcinoma: an exploratory proteomic study., PMID:39011654
Identification of Differentially Expressed mRNAs and lncRNAs Contributes to Elucidation of Underlying Pathogenesis and Therapeutic Strategy of Recurrent Implantation Failure., PMID:38955937
Association between genetic polymorphisms in fibrinogen genes and bleeding risk in patients treated with direct oral anticoagulants., PMID:38904499
Gastric dysplastic lesions in Helicobacter pylori-naïve stomach: Foveolar-type adenoma and intestinal-type dysplasia., PMID:38837872
Skin proteomic screening and functional analysis of differential proteins associated with coat color in sheep (Ovis aries)., PMID:38754850
Systemic whole transcriptome analysis identified underlying molecular characteristics and regulatory networks implicated in the retina following optic nerve injury., PMID:38750783
Bioinformation Analysis of Differential Expression Proteins in Different Processes of COVID-19., PMID:38717820
Deciphering the similarities and disparities of molecular mechanisms behind respiratory epithelium response to HCoV-229E and SARS-CoV-2 and drug repurposing, a systems biology approach., PMID:38652363
Integration of Urinary Peptidome and Fecal Microbiome to Explore Patient Clustering in Chronic Kidney Disease., PMID:38651370
Immune system-related plasma extracellular vesicles in healthy aging., PMID:38633262