Catalog No.
YHB92401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp21-Phe111
Predicted molecular weight
38.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01213
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Proenkephalin-B, Beta-neoendorphin-dynorphin, Preprodynorphin, Alpha-neoendorphin, Beta-neoendorphin, Big dynorphin, Big Dyn, Dynorphin A(1-17), Dyn-A17, Dynorphin A, Dynorphin A(1-13), Dynorphin A(1-8), Leu-enkephalin, Rimorphin, Dynorphin B, Dyn-B, Dynorphin B(1-13), Leumorphin, Dynorphin B-29, PDYN
Enhanced dynorphin expression and secretion in pancreatic beta-cells under hyperglycemic conditions., PMID:39736444
Deciphering Peripheral Taste Neuron Diversity: Using Genetic Identity to Bridge Taste Bud Innervation Patterns and Functional Responses., PMID:39379155
Endogenous opioid signalling regulates spinal ependymal cell proliferation., PMID:39294372
Genetic Variants in KNDy Pathway Lack Association with Premature Ovarian Insufficiency in Mexican Women: A Sequencing-Based Cohort Study., PMID:38927724
Social Isolation Induces Changes in the Monoaminergic Signalling in the Rat Medial Prefrontal Cortex., PMID:38920671
Endogenous opioids in the olfactory tubercle and their roles in olfaction and quality of life., PMID:38872907
A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function., PMID:38802592
Estrogen promotes gonadotropin-releasing hormone expression by regulating tachykinin 3 and prodynorphin systems in chicken., PMID:38759565
Maternal Substance Use and Early-Life Adversity: Inducing Drug Dependence in Offspring, Interactions, Mechanisms, and Treatments., PMID:38651025
Pre-proenkephalin 1 is Downregulated Under Unloading and is Involved in Osteoblast Biology., PMID:38506955
Chronic Exposure to E-Cigarettes Elevates CYP2A5 Activity, Protein Expression, and Cotinine-Induced Production of Reactive Oxygen Species in Mice., PMID:38195520
Tonantzitlolone B Modulates the Endogenous Opioid System to Promote Antinociception in Mice., PMID:37948340
Temporally specific gene expression and chromatin remodeling programs regulate a conserved Pdyn enhancer., PMID:37938195
Effect of PDYN and OPRK1 polymorphisms on the risk of alcohol use disorder and the intensity of depressive symptoms., PMID:37177778
The Involvement of Endogenous Enkephalins in Glucose Homeostasis., PMID:36979650
Acetaminophen improves tardive akathisia induced by dopamine D2 receptor antagonists., PMID:36522124
Organisation of enkephalin inputs and outputs of the central nucleus of the amygdala in mice., PMID:36182026
Transcriptional Regulatory Role of NELL2 in Preproenkephalin Gene Expression., PMID:35950455
Cellular Profiles of Prodynorphin and Preproenkephalin mRNA-Expressing Neurons in the Anterior Olfactory Tubercle of Mice., PMID:35937204
Cerebrospinal fluid levels of proenkephalin and prodynorphin are differentially altered in Huntington's and Parkinson's disease., PMID:35737109
Short Tandem Repeat Variation in the CNR1 Gene Associated With Analgesic Requirements of Opioids in Postoperative Pain Management., PMID:35360861
Moderation of buprenorphine therapy for cocaine dependence efficacy by variation of the Prodynorphin gene., PMID:35218405
Prodynorphin and Proenkephalin in Cerebrospinal Fluid of Sporadic Creutzfeldt-Jakob Disease., PMID:35216166
The Expression Pattern of Genes Related to Melanogenesis and Endogenous Opioids in Psoriasis., PMID:34884858
Heme oxygenase-1 in the spinal cord plays crucial roles in the analgesic effects of pregabalin and gabapentin in a spared nerve-injury mouse model., PMID:34736722
Refeeding activates neurons in the dorsomedial hypothalamus to inhibit food intake and promote positive valence., PMID:34728342
Epigenetic and Transcriptional Control of the Opioid Prodynorphine Gene: In-Depth Analysis in the Human Brain., PMID:34200173
Striatal TRPV1 activation by acetaminophen ameliorates dopamine D2 receptor antagonist-induced orofacial dyskinesia., PMID:33857021
Pituitary neuropeptides and B lymphocyte function., PMID:33817820
Parabrachial opioidergic projections to preoptic hypothalamus mediate behavioral and physiological thermal defenses., PMID:33667158
Cerebrospinal Fluid Markers of Medium Spiny Neuron Injury in Huntington's Disease., PMID:33599006
Regulation of Opioid Receptors by Their Endogenous Opioid Peptides., PMID:33389463
Pre-locus coeruleus neurons in rat and mouse., PMID:33296280
Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23., PMID:33043513
Cerebrospinal Fluid Levels of Prodynorphin-Derived Peptides are Decreased in Huntington's Disease., PMID:33006791
Effect and mechanism of high-fat diet on the preference for sweeteners on mice., PMID:32901966
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function., PMID:32769209
Proenkephalin A 119-159 May Predict Post-operative Acute Kidney Injury and in Hospital Mortality Following Open or Endovascular Thoraco-abdominal Aortic Repair., PMID:32660805
Efferent projections of Vglut2, Foxp2, and Pdyn parabrachial neurons in mice., PMID:32621762
Input-output connections of LJA5 prodynorphin neurons., PMID:32602558
Prodynorphin (PDYN) gene polymorphisms in Turkish patients with methamphetamine use disorder, changes in PDYN serum levels in withdrawal and the relationship between PDYN, temperament and depression., PMID:32597371
Transplantation of Mesenchymal Stromal Cells Expressing the Human Preproenkephalin Gene Can Relieve Pain in a Rat Model of Neuropathic Pain., PMID:32529390
Five Decades of Research on Opioid Peptides: Current Knowledge and Unanswered Questions., PMID:32487735
A neural circuit mechanism for mechanosensory feedback control of ingestion., PMID:32296182
Let-7b-5p promotes electroacupuncture tolerance by downregulating Penk1 gene in CFA-induced inflammatory nociception rats., PMID:32184167
Expression of genes for Kisspeptin (KISS1), Neurokinin B (TAC3), Prodynorphin (PDYN), and gonadotropin inhibitory hormone (RFRP) across natural puberty in ewes., PMID:32170819
Neuropathic Pain Dysregulates Gene Expression of the Forebrain Opioid and Dopamine Systems., PMID:32026358
Proenkephalin Compared to Conventional Methods to Assess Kidney Function in Critically Ill Sepsis Patients., PMID:31977957
Dynorphin and Enkephalin Opioid Peptides and Transcripts in Spinal Cord and Dorsal Root Ganglion During Peripheral Inflammatory Hyperalgesia and Allodynia., PMID:31931229
Early exposure to environmental enrichment modulates the effects of prenatal ethanol exposure upon opioid gene expression and adolescent ethanol intake., PMID:31926456
For research use only. Not for human or drug use.
