Catalog No.
YHB79501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala12-Lys75
Predicted molecular weight
35.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95931
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Chromobox protein homolog 7, CBX7
DNMT1-Induced Downregulation of CBX7 Inhibits ERK Phosphorylation and Promotes Pancreatic Ductal Adenocarcinoma Progression., PMID:40387566
Unraveling the molecular mechanisms of paclitaxel in high-grade serous ovarian cancer through network pharmacology., PMID:40355485
Chromobox protein homolog 7 suppresses the stem-like phenotype of glioblastoma cells by regulating the myosin heavy chain 9-NF-κB signaling pathway., PMID:39988672
A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells., PMID:39799569
CBX7 inhibitors affect H3K9 methyltransferase-regulated gene repression in leukemic cells., PMID:39613290
The Mechanism by Which Hedgehog Interacting Protein (HHIP) in Cancer-Associated Fibroblasts Regulate the Secretion of Inflammatory Factors Through the JAK1/STAT3 Pathway Affecting Prostate Cancer Stemness., PMID:39553307
RNF2 promotes chondrosarcoma progression by regulating ubiquitination and degradation of CBX7., PMID:39456039
Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations., PMID:39402138
Study on the Role of EPHB6 in Inhibiting the Malignant Progression of Cervical Cancer C33A Cells by Binding to CBX7., PMID:39322790
CBX7 promotes choroidal neovascularization by activating the HIF-1α/VEGF pathway in choroidal vascular endothelial cells., PMID:39179168
A novel nanoplatform-based circCSNK1G3 affects CBX7 protein and promotes glioma cell growth., PMID:39033888
Targeting the Ferroptosis and Endoplasmic Reticulum Stress Signaling Pathways by CBX7 in Myocardial Ischemia/reperfusion Injury., PMID:38809351
Retraction: Regulation of circGOLPH3 and its binding protein CBX7 on the proliferation and apoptosis of prostate cancer cells., PMID:38757215
CBX7 silencing promoted liver regeneration by interacting with BMI1 and activating the Nrf2/ARE signaling pathway., PMID:38744845
The predictive significance of chromobox family members in prostate cancer in humans., PMID:38427207
How CBX proteins regulate normal and leukemic blood cells., PMID:38426219
LncRNA RNA ROR Aggravates Hypoxia/Reoxygenation-Induced Cardiomyocyte Ferroptosis by Targeting miR-769-5p/CBX7 Axis., PMID:38157079
Decoding the interaction between miR-19a and CBX7 focusing on the implications for tumor suppression in cancer therapy., PMID:38112798
Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells., PMID:38037081
CBX7 is involved in the progression of cervical cancer through the ITGβ3/TGFβ1/AKT pathway., PMID:38028179
Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells., PMID:37986971
Letter by Zhang et al Regarding Article, "Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis"., PMID:37956225
Response by Cho and Yoon to Letter Regarding Article, "Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis"., PMID:37956224
CBX7 reprograms metabolic flux to protect against meningioma progression by modulating the USP44/c-MYC/LDHA axis., PMID:37791390
Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation., PMID:37756159
Cbx7 promotes the generation of induced pluripotent stem cells., PMID:37753387
Subcellular expression pattern and clinical significance of CBX2 and CBX7 in breast cancer subtypes., PMID:37553450
Identification of the Prognostic Biomarkers CBX6 and CBX7 in Bladder Cancer., PMID:37189494
Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis., PMID:37158107
Increased sinusoidal pressure impairs liver endothelial mechanosensing, uncovering novel biomarkers of portal hypertension., PMID:37151732
Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats., PMID:37077353
PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1., PMID:37030288
Comprehensive analysis reveals the value of the expression of chromobox family members for bladder urothelial carcinoma prognosis., PMID:36970607
CBX7 Rejuvenates Late Passage Dental Pulp Stem Cells by Maintaining Stemness and Pro-angiogenic Ability., PMID:36920677
Chromobox Family Proteins as Putative Biomarkers for Breast Cancer Management: A Preliminary Study Based on Bioinformatics Analysis and qRT-PCR Validation., PMID:36605919
Corrigendum: P14AS upregulates gene expression in the CDKN2A/2B locus through competitive binding to PcG protein CBX7., PMID:36568974
Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer., PMID:36396821
Integrated analysis of potential gene crosstalk between non-alcoholic fatty liver disease and diabetic nephropathy., PMID:36387855
Mining Transcriptomic Data to Uncover the Association between CBX Family Members and Cancer Stemness., PMID:36361869
CBX Family Members in Two Major Subtypes of Renal Cell Carcinoma: A Comparative Bioinformatic Analysis., PMID:36292141
Overexpression of gamma glutamyl hydrolase predicts extranodal extension in squamous cell carcinoma of the oral cavity., PMID:36229363
Knockdown of CBX7 inhibits ferroptosis in rats with cerebral ischemia and improves cognitive dysfunction by activating the Nrf2/HO-1 pathway., PMID:36222130
Systematic investigation of the clinical significance and prognostic value of the CBXs in esophageal cancer., PMID:36221371
Pan-cancer analysis of Chromobox (CBX) genes for prognostic significance and cancer classification., PMID:36183965
P14AS upregulates gene expression in the CDKN2A/2B locus through competitive binding to PcG protein CBX7., PMID:36176277
The expression of miR-181b, CYLD, CBX-7, BCL2, and p53 in osteosarcoma patients and correlation with clinicopathological factors., PMID:36098711
FLT3LG and IFITM3P6 consolidate T cell activity in the bone marrow microenvironment and are prognostic factors in acute myelocytic leukemia., PMID:36081495
Inhibition of Gap Junctional Intercellular Communication Upregulates Pluripotency Gene Expression in Endogenous Pluripotent Muse Cells., PMID:36078111
Identification and validation of differentially expressed chromatin regulators for diagnosis of aortic dissection using integrated bioinformatics analysis and machine-learning algorithms., PMID:36035141
Chromobox 7/8 serve as independent indicators for glioblastoma via promoting proliferation and invasion of glioma cells., PMID:36034290
For research use only. Not for human or drug use.
