Catalog No.
YHB72601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly235-Val433
Predicted molecular weight
25.21 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95718
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ERR-beta, NR3B2, Estrogen-related receptor beta, ESRL2, Estrogen receptor-like 2, ERR beta-2, ESRRB, Nuclear receptor subfamily 3 group B member 2, Steroid hormone receptor ERR2, ERRB2
Expression and prognostic value of estrogen-related receptor β alternative splicing isoforms in esophageal squamous cell carcinoma., PMID:40335994
Rewiring of SINE-MIR enhancer topology and Esrrb modulation in expanded and naive pluripotency., PMID:40296153
Tetramethyl bisphenol F exposure induces human ovarian granulosa cell senescence and mouse ovarian damage by regulating ESRRB signalling., PMID:40014986
ERK phosphorylates ESRRB to regulate the self-renewal and differentiation of mouse embryonic stem cells., PMID:39919750
Reconstitution of pluripotency from mouse fibroblast through Sall4 overexpression., PMID:39737935
Endometrial expression of ERRβ and ERRγ: prognostic significance and clinical correlations in severe endometriosis., PMID:39678195
A suboptimal OCT4-SOX2 binding site facilitates the naïve-state specific function of a Klf4 enhancer., PMID:39348365
Functional pathogenicity of ESRRB variant of uncertain significance contributes to hearing loss (DFNB35)., PMID:39261511
Effect of the gonadotropin surge on steroid receptor regulation in preovulatory follicles and newly formed corpora lutea in the cow., PMID:39047595
Perfluorooctanesulfonic acid (PFOS) induced cancer related DNA methylation alterations in human breast cells: A whole genome methylome study., PMID:39032741
The transcription factor OCT6 promotes the dissolution of the naïve pluripotent state by repressing Nanog and activating a formative state gene regulatory network., PMID:38710730
Mitotic bookmarking by transcription factors: be aware of redundancy., PMID:38503673
Glycolysis-Stimulated Esrrb Lactylation Promotes the Self-Renewal and Extraembryonic Endoderm Stem Cell Differentiation of Embryonic Stem Cells., PMID:38473939
SIRT1 mediates breast cancer development and tumorigenesis controlled by estrogen-related receptor β., PMID:38421553
Identification of common stria vascularis cellular alteration in sensorineural hearing loss based on ScRNA-seq., PMID:38413848
Mitotic bookmarking redundancy by nuclear receptors in pluripotent cells., PMID:38196033
SETD5 regulates the OGT-catalyzed O-GlcNAcylation of RNA polymerase II, which is involved in the stemness of colorectal cancer cells., PMID:37963940
Complex haploinsufficiency in pluripotent cells yields somatic cells with DNA methylation abnormalities and pluripotency induction defects., PMID:37832543
Rat post-implantation epiblast-derived pluripotent stem cells produce functional germ cells., PMID:37671016
Total flavonoids of Rhizoma drynariae improves tendon-bone healing for anterior cruciate ligament reconstruction in mice and promotes the osteogenic differentiation of bone mesenchymal stem cells by the ERR1/2-Gga1-TGF-β/MAPK pathway., PMID:37665165
A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation., PMID:37633265
ESRRB Inhibits the TGFβ Signaling Pathway to Drive Cell Proliferation in Cervical Cancer., PMID:37350664
Structural mechanism of LIN28B nucleosome targeting by OCT4., PMID:37327775
Integrated Bioinformatics Analysis for the Identification of Key lncRNAs, mRNAs, and Potential Drugs in Clear Cell Renal Cell Carcinomas., PMID:37275334
Long Noncoding RNA ACTA2-AS1 Inhibits Cell Growth and Facilitates Apoptosis in Gastric Cancer by Binding with miR-6720-5p to Regulate ESRRB., PMID:37222961
The NuRD complex cooperates with SALL4 to orchestrate reprogramming., PMID:37208322
Retinoblastoma gene expression profiling based on bioinformatics analysis., PMID:37179305
Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis., PMID:37155882
Esrrb guides naive pluripotent cells through the formative transcriptional programme., PMID:37106060
Loss of H3K9 trimethylation alters chromosome compaction and transcription factor retention during mitosis., PMID:36941433
ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control., PMID:36542664
Identification of recurrent variants implicated in disease in bicuspid aortic valve patients through whole-exome sequencing., PMID:36071494
Esrrb Regulates Specific Feed-Forward Loops to Transit From Pluripotency Into Early Stages of Differentiation., PMID:35652095
A novel missense variant in ESRRB gene causing autosomal recessive non-syndromic hearing loss: in silico analysis of a case., PMID:35101039
Association of Estrogen-Related Polygenetic Risk Scores with Breast Cancer and Interactions with Alcohol Intake, Early Menarche, and Nulligravida., PMID:35092367
Differential repression of Otx2 underlies the capacity of NANOG and ESRRB to induce germline entry., PMID:34971561
Loss of Resf1 reduces the efficiency of embryonic stem cell self-renewal and germline entry., PMID:34607919
Identification and inference for subgroups with differential treatment efficacy from randomized controlled trials with survival outcomes through multiple testing., PMID:34542190
The combined action of Esrrb and Nr5a2 is essential for murine naïve pluripotency., PMID:34397088
Association Analysis of Candidate Gene Polymorphisms and Tinnitus in Young Musicians., PMID:34282101
Novel pathogenic mutations and further evidence for clinical relevance of genes and variants causing hearing impairment in Tunisian population., PMID:34194829
AP-1 activity is a major barrier of human somatic cell reprogramming., PMID:34181046
Effects of Fruquintinib on the Pluripotency Maintenance and Differentiation Potential of Mouse Embryonic Stem Cells., PMID:34077681
YY2 in Mouse Preimplantation Embryos and in Embryonic Stem Cells., PMID:34066930
Oocyte-specific linker histone H1foo interacts with Esrrb to induce chromatin decondensation at specific gene loci., PMID:34023782
Cooperation between HDAC3 and DAX1 mediates lineage restriction of embryonic stem cells., PMID:33909924
An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions., PMID:33816475
Cruciform Formable Sequences within Pou5f1 Enhancer Are Indispensable for Mouse ES Cell Integrity., PMID:33810223
Estrogen receptor β and treatment with a phytoestrogen are associated with inhibition of nuclear translocation of EGFR in the prostate., PMID:33771918
For research use only. Not for human or drug use.
