Catalog No.
YHB69601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp438-Ala628
Predicted molecular weight
23.40 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95602
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DNA-directed RNA polymerase I subunit RPA1, RNA polymerase I subunit A1, 2.7.7.6, A190, DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I subunit A, RNA polymerase I 194 kDa subunit, RPA194, POLR1A
Evolutionary and Structural Insights into the RNA Polymerase I A34 Protein Family: A Focus on Intrinsic Disorder and Phase Separation., PMID:39858608
A role for the kinetochore protein, NUF2, in ribosome biogenesis., PMID:39705402
(Re-)Viewing Role of Intracellular Glucose Beyond Extracellular Regulation of Glucose-Stimulated Insulin Secretion by Pancreatic Cells., PMID:38496986
A homozygous POLR1A variant causes leukodystrophy and affects protein homeostasis., PMID:36917474
Small molecule-mediated disruption of ribosome biogenesis synergizes with FGFR inhibitors to suppress glioma cell growth., PMID:36583853
Blood Transcriptome Analysis of Beef Cow with Different Parity Revealed Candidate Genes and Gene Networks Regulating the Postpartum Diseases., PMID:36140838
Autophagy regulates rRNA synthesis., PMID:35993412
Common Core Genes Play Vital Roles in Gastric Cancer With Different Stages., PMID:35938042
Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development., PMID:35881792
A high-throughput assay for directly monitoring nucleolar rRNA biogenesis., PMID:35078352
NF-κB-Related Metabolic Gene Signature Predicts the Prognosis and Immunotherapy Response in Gastric Cancer., PMID:35036435
Phenotypic and Molecular Heterogeneity in Mandibulofacial Dysostoses: A Case Series From India., PMID:34714179
Autophagy deficiency activates rDNA transcription., PMID:34612149
The plasma peptides of Alzheimer's disease., PMID:34182925
Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer., PMID:32396863
Lysine-specific demethylase 2A enhances binding of various nuclear factors to CpG-rich genomic DNAs by action of its CXXC-PHD domain., PMID:30940825
Increased expression of NAF1 contributes to malignant phenotypes of glioma cells through promoting protein synthesis and associates with poor patient survival., PMID:30936423
tp53-dependent and independent signaling underlies the pathogenesis and possible prevention of Acrofacial Dysostosis-Cincinnati type., PMID:29750247
miR-424-5p reduces ribosomal RNA and protein synthesis in muscle wasting., PMID:29215200
Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A., PMID:28051070
CNVs leading to fusion transcripts in individuals with autism spectrum disorder., PMID:22549408
Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance., PMID:22367191
Selective inhibition of rRNA transcription downregulates E2F-1: a new p53-independent mechanism linking cell growth to cell proliferation., PMID:21878508
The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells., PMID:21399665
For research use only. Not for human or drug use.
