Catalog No.
YHB41901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr41-His149
Predicted molecular weight
40.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O76096
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cystatin-F, Cystatin-7, Cystatin-like metastasis-associated protein, CMAP, Leukocystatin, CST7
Identification of CD19+B Cell as a Diagnostic Biomarker in Sepsis-Induced ARDS., PMID:40503488
MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury., PMID:40151877
Immune and vascular modulation by HERVs: the role of CXCR1 and IL18RAP in dengue severity progression., PMID:40124360
The DHH-DHHA1 domain phosphodiesterase of Mycoplasma bovis employs multiple strategies to modulate macrophage cellular processes., PMID:40023422
POU2F2+ B cells enhance antitumor immunity and predict better survival in non small cell lung cancer., PMID:39994401
Analysis and validation of programmed cell death genes associated with spinal cord injury progression based on bioinformatics and machine learning., PMID:39929099
Spatiotemporal Dysregulation of Neuron-Glia Related Genes and Pro-/Anti-Inflammatory miRNAs in the 5xFAD Mouse Model of Alzheimer's Disease., PMID:39273422
Integrated analyses reveal CST7 and DUSP5 regulate Th2 cells differentiation to promote chronic HBV infection., PMID:39237681
Interferon-responsive neutrophils and macrophages extricate SARS-CoV-2 Omicron critical patients from the nasty fate of sepsis., PMID:39206862
Cystatin F Depletion in Mycobacterium tuberculosis-Infected Macrophages Improves Cathepsin C/Granzyme B-Driven Cytotoxic Effects on HIV-Infected Cells during Coinfection., PMID:39125711
Cystatin F attenuates neuroinflammation and demyelination following murine coronavirus infection of the central nervous system., PMID:38879499
CXCR6-positive circulating mucosal-associated invariant T cells can identify patients with non-small cell lung cancer responding to anti-PD-1 immunotherapy., PMID:38698468
Alterations in Alzheimer's disease microglia transcriptome might be involved in bone pathophysiology., PMID:38184014
Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer's disease., PMID:38085657
A bidirectional link between sulfatide and Alzheimer's disease., PMID:37972592
Glioblastoma survival is associated with distinct proteomic alteration signatures post chemoirradiation in a large-scale proteomic panel., PMID:37637066
Single-cell RNA sequencing reveals the transcriptomic characteristics of peripheral blood mononuclear cells in hepatitis B vaccine non-responders., PMID:37593735
Microglial activation protects against accumulation of tau aggregates in nondemented individuals with underlying Alzheimer's disease pathology., PMID:37118533
Novel Potential Mechanisms of Regulatory B Cell-Mediated Immunosuppression., PMID:37068869
Nasal administration of anti-CD3 mAb (Foralumab) downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells in subjects with COVID-19., PMID:36881624
Sex-specific role for microglial CST7 in Alzheimer's disease., PMID:36596847
Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease., PMID:36448627
Specific signature biomarkers highlight the potential mechanisms of circulating neutrophils in aneurysmal subarachnoid hemorrhage., PMID:36438795
Single-cell RNA sequencing analysis of T helper cell differentiation and heterogeneity., PMID:35779629
Characterization of Peripheral Blood TCR in Patients with Type 1 Diabetes Mellitus by BD RhapsodyTM VDJ CDR3 Assay., PMID:35626661
Genome-Wide Identification of Associations of Circulating Molecules With Spontaneous Coronary Artery Dissection and Aortic Aneurysm and Dissection., PMID:35571188
Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer., PMID:34980144
An early proinflammatory transcriptional response to tau pathology is age-specific and foreshadows reduced tau burden., PMID:34463402
Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery., PMID:34412701
Lung but not brain cancer cell malignancy inhibited by commonly used anesthetic propofol during surgery: Implication of reducing cancer recurrence risk., PMID:34194828
Cystatin F acts as a mediator of immune suppression in glioblastoma., PMID:34189679
Expression of Ripk1 and DAM genes correlates with severity and progression of Krabbe disease., PMID:34172992
Transcriptomic Profiling Identifies Neutrophil-Specific Upregulation of Cystatin F as a Marker of Acute Inflammation in Humans., PMID:33868254
Unique Subtype of Microglia in Degenerative Thalamus After Cortical Stroke., PMID:33412903
Exploring the factors underlying remyelination arrest by studying the post-transcriptional regulatory mechanisms of cystatin F gene., PMID:32947653
Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system., PMID:32449994
Characterization of the chromatin accessibility in an Alzheimer's disease (AD) mouse model., PMID:32293531
Investigation of the clinical significance and prospective molecular mechanisms of cystatin genes in patients with hepatitis B virus‑related hepatocellular carcinoma., PMID:31115549
Cystatin F as a key family 2 cystatin subunit and prognostic biomarker for early‑stage pancreatic ductal adenocarcinoma., PMID:31059105
Increased cystatin F levels correlate with decreased cytotoxicity of cytotoxic T cells., PMID:30840596
Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia., PMID:30340518
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden., PMID:30283032
[Bioinformatics analysis of genes related to pathogenesis of major depression disorder]., PMID:30112561
The transcription factor C/EBP α controls the role of cystatin F during the differentiation of monocytes to macrophages., PMID:30033148
Transcriptomic signatures of cellular and humoral immune responses in older adults after seasonal influenza vaccination identified by data-driven clustering., PMID:29335477
RIPK1 mediates a disease-associated microglial response in Alzheimer's disease., PMID:28904096
Low-level internalization of cystatin E/M affects legumain activity and migration of melanoma cells., PMID:28630039
Cystatin F is a biomarker of prion pathogenesis in mice., PMID:28178353
Differential Expression of Ccn4 and Other Genes Between Metastatic and Non-metastatic EL4 Mouse Lymphoma Cells., PMID:27807066
Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F., PMID:26247631