Catalog No.
YHB31901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln230-Asn320
Predicted molecular weight
38.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75821
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Eukaryotic translation initiation factor 3 subunit 4, eIF-3-delta, eIF3 p42, eIF3 p44, EIF3G, EIF3S4
Yeast Eukaryotic Initiation Factor 4B Remodels the MRNA Entry Site on the Small Ribosomal Subunit., PMID:39847343
40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion., PMID:39803544
N6-methyladenosine in 28S rRNA promotes oncogenic mRNA translation and tyrosine catabolism., PMID:39739529
Four ClEF1A genes involved in self-incompatibility in 'Xiangshui Lemon' confer early fowering and increase stress tolerance in transgenic Arabidopsis., PMID:39546946
Potential mechanisms for predicting comorbidity between multiple myeloma and femoral head necrosis based on multiple bioinformatics., PMID:39405776
Arabidopsis Fhit-like tumor suppressor resumes early terminated constitutive triple response1-10 mRNA translation., PMID:38563472
In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g., PMID:37821106
An interaction between eIF4A3 and eIF3g drives the internal initiation of translation., PMID:37811880
Dissecting the roles of EIF4G homologs reveals DAP5 as a modifier of CGG repeat-associated toxicity in a Drosophila model of FXTAS., PMID:37352983
In vitro reconstitution of SARS CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g., PMID:37292671
Suppression of CCT3 Inhibits Tumor Progression by Impairing ATP Production and Cytoplasmic Translation in Lung Adenocarcinoma., PMID:35409343
Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation., PMID:34260917
Long non-coding RNA LINC02446 suppresses the proliferation and metastasis of bladder cancer cells by binding with EIF3G and regulating the mTOR signalling pathway., PMID:33526846
Dysregulated healing responses in diabetic wounds occur in the early stages postinjury., PMID:33350981
CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev., PMID:33103564
Knockdown of RPL34 suppresses osteosarcoma cell proliferation likely through EIF3/FAU signaling pathway., PMID:35116824
Eukaryotic translation initiation factor 3 subunit G (EIF3G) resensitized HCT116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1., PMID:30214237
Hypodermal responses to protein synthesis inhibition induce systemic developmental arrest and AMPK-dependent survival in Caenorhabditis elegans., PMID:30020921
A yeast two-hybrid assay reveals CMYA1 interacting proteins., PMID:28728781
Rare missense mutations in P2RY11 in narcolepsy with cataplexy., PMID:28460015
eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition., PMID:27373335
The Rice Eukaryotic Translation Initiation Factor 3 Subunit f (OseIF3f) Is Involved in Microgametogenesis., PMID:27200010
Nuclear distribution of eIF3g and its interacting nuclear proteins in breast cancer cells., PMID:26935993
Proteome Analysis of Ground State Pluripotency., PMID:26671762
EIF3G is associated with narcolepsy across ethnicities., PMID:25669430
NIa-Pro of Papaya ringspot virus interacts with Carica papaya eukaryotic translation initiation factor 3 subunit G (CpeIF3G)., PMID:25416301
The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition., PMID:25166596
Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase., PMID:24396066
Evidence for the role of wheat eukaryotic translation initiation factor 3 subunit g (TaeIF3g) in abiotic stress tolerance., PMID:24084365
Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g)., PMID:24080033
Spectrin domain of eukaryotic initiation factor 3a is the docking site for formation of the a:b:i:g subcomplex., PMID:23921387
Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins., PMID:23804756
Translation initiation on mRNAs bound by nuclear cap-binding protein complex CBP80/20 requires interaction between CBP80/20-dependent translation initiation factor and eukaryotic translation initiation factor 3g., PMID:22493286
A set of host proteins interacting with papaya ringspot virus NIa-Pro protein identified in a yeast two-hybrid system., PMID:22404606
Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly., PMID:22090426
[Construction and application of inducible artificial microRNA expression vector targeting eIF3g gene]., PMID:21315039
Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach., PMID:21285413
The RNA recognition motif of eukaryotic translation initiation factor 3g (eIF3g) is required for resumption of scanning of posttermination ribosomes for reinitiation on GCN4 and together with eIF3i stimulates linear scanning., PMID:20679478
Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton., PMID:20406461
Fission yeast translation initiation factor 3 subunit eIF3h is not essential for global translation initiation, but deletion of eif3h+ affects spore formation., PMID:19061185
Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation., PMID:18725400
Reconstitution reveals the functional core of mammalian eIF3., PMID:17581632
The fission yeast ortholog of eIF3a subunit is not functional in Saccharomyces cerevisiae., PMID:17455792
Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3 subunit p44 (eIF3g)., PMID:17094969
Control of translation reinitiation on the cauliflower mosaic virus (CaMV) polycistronic RNA., PMID:15270684
Eucaryotic initiation factor 4B controls eIF3-mediated ribosomal entry of viral reinitiation factor., PMID:14988734
Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3., PMID:14519125
A plant viral "reinitiation" factor interacts with the host translational machinery., PMID:11572778
Fission yeast homolog of murine Int-6 protein, encoded by mouse mammary tumor virus integration site, is associated with the conserved core subunits of eukaryotic translation initiation factor 3., PMID:11134033