Catalog No.
YHB27501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu87-Asp141
Predicted molecular weight
34.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75638
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cancer/testis antigen 2, CT2, Autoimmunogenic cancer/testis antigen NY-ESO-2, Cancer/testis antigen 6.2, CT6.2, L antigen family member 1, LAGE-1, CTAG2, ESO2, LAGE1
Enhancing antitumor response by efficiently generating large-scale TCR-T cells targeting a single epitope across multiple cancer antigens., PMID:38733699
Decreased Expression of PLD2 Promotes EMT in Colorectal Cancer Invasion and Metastasis., PMID:38706911
Identification of an 8 HPV-related RNA signature as a novel prognostic biomarker for squamous cell carcinoma of the head and neck., PMID:38335428
Comprehensive multiplexed autoantibody profiling of patients with advanced urothelial cancer., PMID:38309723
Identification of Novel Characteristics in TP53-Mutant Hepatocellular Carcinoma Using Bioinformatics., PMID:35651938
Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients., PMID:35565356
Specific Inhibition of Tumor Growth by T Cell Receptor-Drug Conjugates Targeting Intracellular Cancer-Testis Antigen NY-ESO-1/LAGE-1., PMID:33237767
Identification of cancer/testis antigen 2 gene as a potential hepatocellular carcinoma therapeutic target by hub gene screening with topological analysis., PMID:31611988
Genome‑wide investigation of the clinical implications and molecular mechanism of long noncoding RNA LINC00668 and protein‑coding genes in hepatocellular carcinoma., PMID:31432149
Expression of cancer-testis antigens in esophageal cancer and their progress in immunotherapy., PMID:30656409
Tumor-associated autoantibodies as early detection markers for ovarian cancer? A prospective evaluation., PMID:29473162
Analysis of infantile fibrosarcoma reveals extensive T-cell responses within tumors: Implications for immunotherapy., PMID:28921877
Systematic review: Tumor-associated antigen autoantibodies and ovarian cancer early detection., PMID:28800944
The Prevalence of Cancer-Associated Autoantibodies in Patients with Gastric Cancer and Progressive Grades of Premalignant Lesions., PMID:28768706
Autoantibody biomarkers for the detection of serous ovarian cancer., PMID:28427776
Adjuvant Autologous Melanoma Vaccine for Macroscopic Stage III Disease: Survival, Biomarkers, and Improved Response to CTLA-4 Blockade., PMID:27294163
The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion., PMID:26895102
Melanoma Cells Control Antimelanoma CTL Responses via Interaction between TIGIT and CD155 in the Effector Phase., PMID:26763445
NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma., PMID:26193344
Plasma Autoantibodies Associated with Basal-like Breast Cancers., PMID:26070530
Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model., PMID:24885297
Development of a novel, quantitative protein microarray platform for the multiplexed serological analysis of autoantibodies to cancer-testis antigens., PMID:24604332
Expression of cancer-testis antigens MAGEA1, MAGEA3, ACRBP, PRAME, SSX2, and CTAG2 in myxoid and round cell liposarcoma., PMID:24457462
MAGE-A3 is highly expressed in a subset of colorectal cancer patients., PMID:23390371
Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors., PMID:23263452
Expression of MAGE-A3, NY-ESO-1, LAGE-1 and PRAME in urothelial carcinoma., PMID:22596240
NYESO-1/LAGE-1s and PRAME are targets for antigen specific T cells in chondrosarcoma following treatment with 5-Aza-2-deoxycitabine., PMID:22384167
Cancer testis antigens: novel biomarkers and targetable proteins for ovarian cancer., PMID:21557639
Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma., PMID:21551254
Evaluation of LAGE-1 and NY-ESO-1 expression in multiple myeloma patients to explore possible benefits of their homology for immunotherapy., PMID:21247062
Epitope hierarchy of spontaneous CD4+ T cell responses to LAGE-1., PMID:21131422
Yeast-based identification of prostate tumor antigens provides an effective vaccine platform., PMID:20393012
Comparisons for detecting NY-ESO-1 mRNA expression levels in hepatocellular carcinoma tissues., PMID:19212631
Seromic analysis of antibody responses in non-small cell lung cancer patients and healthy donors using conformational protein arrays., PMID:19041653
Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients., PMID:18237105
Identification and expression analysis of novel LAGE-1 alleles with single nucleotide polymorphisms in cancer patients., PMID:17899192
Quantifying and imaging NY-ESO-1/LAGE-1-derived epitopes on tumor cells using high affinity T cell receptors., PMID:16751374
A new specific gene expression in squamous cell carcinoma of the esophagus detected using representational difference analysis and cDNA microarray., PMID:16446548
Antimetastatic gene expression profiles mediated by retinoic acid receptor beta 2 in MDA-MB-435 breast cancer cells., PMID:16255778
A new LAGE-1 peptide recognized by cytolytic T lymphocytes on HLA-A68 tumors., PMID:16187088
[Expression of NY-ESO-1 and LAGE-1 cancer-testis antigens in hepatocellular carcinoma]., PMID:16091172
Expression profile of cancer-testis genes in 121 human colorectal cancer tissue and adjacent normal tissue., PMID:15756003
[Expression of NY-ESO-1/LAGE-1 genes in hepatocellular carcinoma and autologous humoral responses induced thereby]., PMID:15730810
Naturally acquired MAGE-A10- and SSX-2-specific CD8+ T cell responses in patients with hepatocellular carcinoma., PMID:15661935
Immunohistochemical and molecular analysis of human melanomas for expression of the human cancer-testis antigens NY-ESO-1 and LAGE-1., PMID:15623618
Cancer/testis antigen expression and autologous humoral immunity to NY-ESO-1 in gastric cancer., PMID:15516106
[Adaptive immunotherapy of the advanced prostate cancer - cancer testis antigen (CTA) as possible target antigens]., PMID:15459874
Identification of multiple HLA-DR-restricted epitopes of the tumor-associated antigen CAMEL by CD4+ Th1/Th2 lymphocytes., PMID:15067093
[Expression of multiple cancer-testis antigen genes in non-small cell lung cancer treated by chemotherapy prior surgery]., PMID:15061963
Serological cloning of cancer/testis antigens expressed in prostate cancer using cDNA phage surface display., PMID:14747957
For research use only. Not for human or drug use.
