Catalog No.
YHB25501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-His148
Predicted molecular weight
19.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75586
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mediator of RNA polymerase II transcription subunit 6, Activator-recruited cofactor 33 kDa component, ARC33, Mediator complex subunit 6, hMed6, Renal carcinoma antigen NY-REN-28, MED6, ARC33
A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria., PMID:39325875
A new strategy for screening novel functional genes involved in reduction of lipid droplet accumulation., PMID:37983968
Regulation of fungal raw-starch-degrading enzyme production depends on transcription factor phosphorylation and recruitment of the Mediator complex., PMID:37828083
Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain., PMID:37014863
Identification of diagnostic genes for both Alzheimer's disease and Metabolic syndrome by the machine learning algorithm., PMID:36405716
Identification of Therapeutic Targets and Prognostic Biomarkers among Genes from the Mediator Complex Family in the Hepatocellular Carcinoma Tumour-Immune Microenvironment., PMID:35069777
Genetic interaction between RLM1 and F-box motif encoding gene SAF1 contributes to stress response in Saccharomyces cerevisiae., PMID:34627408
ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma., PMID:33948561
Differential Requirements for Mediator Complex Subunits in Drosophila melanogaster Host Defense Against Fungal and Bacterial Pathogens., PMID:33746938
Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex., PMID:29992056
Core Mediator structure at 3.4 Å extends model of transcription initiation complex., PMID:28467824
Promotion of Cell Viability and Histone Gene Expression by the Acetyltransferase Gcn5 and the Protein Phosphatase PP2A in Saccharomyces cerevisiae., PMID:27317677
Characterization of the influence of mediator complex in HIV-1 transcription., PMID:25100719
[Study on gene differential expressions of substance and energy metabolism in chronic superficial gastritis patients of Pi deficiency syndrome and of pi-wei hygropyrexia syndrome]., PMID:23185754
Structure of the Mediator head module., PMID:23123849
MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis., PMID:20194623
Mediator subunit MED28 (Magicin) is a repressor of smooth muscle cell differentiation., PMID:17848560
A kinase subunit of the human mediator complex, CDK8, positively regulates transcriptional activation., PMID:17212659
Head module control of mediator interactions., PMID:16885025
Functional and physical interactions within the middle domain of the yeast mediator., PMID:16758199
Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets., PMID:16109375
Clinical electrophysiologic tests and genotype correlations in muscle channelopathies., PMID:16106626
Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans., PMID:15790964
A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer., PMID:15710619
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology., PMID:15175163
Mechanism of destructive pathologic changes in the spinal cord under chronic mechanical compression., PMID:11805631
The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans., PMID:11728440
Biological significance of a universally conserved transcription mediator in metazoan developmental signaling pathways., PMID:11688559
Frameshift mutation in the collagen VI gene causes Ullrich's disease., PMID:11506412
Effect of a neutrophil elastase inhibitor (ONO-5046 Na) on ischemia/reperfusion injury using the left-sided heterotopic canine heart transplantation model., PMID:11502411
Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes., PMID:11438678
HTLV-I Tax related dysfunction of cell cycle regulators and oncogenesis of adult T cell leukemia., PMID:11426548
The TRAP/SMCC/Mediator complex and thyroid hormone receptor function., PMID:11306338
Srb7p is a physical and physiological target of Tup1p., PMID:11118219
Arsenic trioxide and the growth of human T-cell leukemia virus type I infected T-cell lines., PMID:11042529
Suppression of metastasis by thymidine phosphorylase inhibitor., PMID:11034068
A novel mutation of desert hedgehog in a patient with 46,XY partial gonadal dysgenesis accompanied by minifascicular neuropathy., PMID:11017805
The influence of human T lymphotropic virus type I infection on the outcome of cardiovascular surgery., PMID:11003751
Effect of neoadjuvant chemotherapy for lymph node micrometastasis and tumor cell microinvolvement in the patients with esophageal carcinoma., PMID:10996722
Down-regulation of E-cadherin by antisense oligonucleotide enhances basement membrane invasion of pancreatic carcinoma cells., PMID:10937343
Axonal damage revealed by accumulation of beta-amyloid precursor protein in HTLV-I-associated myelopathy., PMID:10930590
Increased expression of vascular endothelial growth factor (VEGF) in Castleman's disease: proposed pathomechanism of vascular proliferation in the affected lymph node., PMID:10830746
Effectiveness of preoperatively obtained autologous platelet concentrates in open heart surgery., PMID:10599957
Different upstream transcriptional activators have distinct coactivator requirements., PMID:10580000
Expression of p21WAF1/Cip1 in the p53-dependent pathway is related to prognosis in patients with advanced esophageal carcinoma., PMID:10499617
Hepatic metastasis of gastroenterological cancer: its tumor biology and oncological surgery., PMID:10481808
NF-kappaB involvement in the activation of primary adult T-cell leukemia cells and its clinical implications., PMID:10390192
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators., PMID:10198638
Expression of vascular endothelial growth factor in sera and lymph nodes of the plasma cell type of Castleman's disease., PMID:10086783
A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation., PMID:10024883
For research use only. Not for human or drug use.
