Catalog No.
YHB20001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Ser263
Predicted molecular weight
31.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75431
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Metaxin-2, Mitochondrial outer membrane import complex protein 2, MTX2
Integration of multi-omics and single-cell transcriptome reveals mitochondrial outer membrane protein-2 (MTX-2) as a prognostic biomarker and characterizes ubiquinone metabolism in lung adenocarcinoma., PMID:40302794
Metaxin-2 tunes mitochondrial transportation and neuronal function in Drosophila., PMID:39657051
Validation of metaxin-2 deficient C. elegans as a model for MandibuloAcral Dysplasia associated to mtx-2 (MADaM) syndrome., PMID:39462037
Axonal mitochondria regulate gentle touch response through control of axonal actin dynamics., PMID:39185223
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients., PMID:38250156
Simultaneous PCR detection of Paenibacillus larvae targeting insertion sequence IS256 and Melissococcus plutonius targeting pMP1 plasmid from hive specimens., PMID:38180723
Structural insight into Bacillus thuringiensis Sip1Ab reveals its similarity to ETX_MTX2 family beta-pore-forming toxin., PMID:37341620
The toxins of vertically transmitted Spiroplasma., PMID:37275155
Mitochondrial cristae architecture protects against mtDNA release and inflammation., PMID:36476853
[Activity of Codonopsis canescens against rheumatoid arthritis based on TLRs/MAPKs/NF-κB signaling pathways and its mechanism]., PMID:36471941
Safety assessment of Mpp75Aa1.1, a new ETX_MTX2 protein from Brevibacillus laterosporus that controls western corn rootworm., PMID:36074780
CARD19 Interacts with Mitochondrial Contact Site and Cristae Organizing System Constituent Proteins and Regulates Cristae Morphology., PMID:35406738
Peptide mediated, enhanced toxicity of a bacterial pesticidal protein against southern green stink bug., PMID:35315236
Structural and functional characterization of Mpp75Aa1.1, a putative beta-pore forming protein from Brevibacillus laterosporus active against the western corn rootworm., PMID:34634061
AREL1 E3 ubiquitin ligase inhibits TNF-induced necroptosis via the ubiquitination of MTX2., PMID:34584540
Production of Lysinibacillus sphaericus Mosquitocidal Protein Mtx2 from Bacillus subtilis as a Secretory Protein., PMID:34137359
Mutations Involved in Premature-Ageing Syndromes., PMID:34103969
Identification of a five gene signature to predict time to biochemical recurrence after radical prostatectomy., PMID:34002865
Identification of oxytocin-related lncRNAs and assessment of their expression in breast cancer., PMID:33742056
Metaxins are core components of mitochondrial transport adaptor complexes., PMID:33397950
Loss of MTX2 causes mandibuloacral dysplasia and links mitochondrial dysfunction to altered nuclear morphology., PMID:32917887
Bacillus thuringiensis novel toxin Epp is toxic to mosquitoes and prodenia litura larvae., PMID:32036551
Glabralysins, Potential New β-Pore-Forming Toxin Family Members from the Schistosomiasis Vector Snail Biomphalaria glabrata., PMID:31936048
Biomarker profile for prediction of response to SMAC mimetic monotherapy in pediatric precursor B-cell acute lymphoblastic leukemia., PMID:31749151
Identification of five novel genetic loci related to facial morphology by genome-wide association studies., PMID:29921221
Recent advancement on chemical arsenal of Bt toxin and its application in pest management system in agricultural field., PMID:29607282
Cry64Ba and Cry64Ca, Two ETX/MTX2-Type Bacillus thuringiensis Insecticidal Proteins Active against Hemipteran Pests., PMID:29150505
Improving insect control protein activity for GM crops: A case study demonstrating that increased target insect potency can be achieved without impacting mammalian safety., PMID:28751263
The phosphorylation of Metaxin 1 controls Bak activation during TNFα induced cell death., PMID:27845183
Wheat Fhb1 encodes a chimeric lectin with agglutinin domains and a pore-forming toxin-like domain conferring resistance to Fusarium head blight., PMID:27776114
The sequence, structural, and functional diversity within a protein family and implications for specificity and safety: The case for ETX_MTX2 insecticidal proteins., PMID:27235983
Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex., PMID:26477565
Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration., PMID:25725288
Bacillus thuringiensis toxins: an overview of their biocidal activity., PMID:25514092
The role of Wnt/β-catenin signaling in enterocyte turnover during methotrexate-induced intestinal mucositis in a rat., PMID:25375224
Relationship between RFC gene expression and intracellular drug concentration in methotrexate-resistant osteosarcoma cells., PMID:25078587
Metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for Bak activation during TNF alpha triggered apoptosis., PMID:24794530
Searching for genomic region of high-fat diet-induced type 2 diabetes in mouse chromosome 2 by analysis of congenic strains., PMID:24789282
Mtx toxins from Lysinibacillus sphaericus enhance mosquitocidal cry-toxin activity and suppress cry-resistance in Culex quinquefasciatus., PMID:24144574
Expression of mosquito-larvicidal toxin genes under the control of a native promoter in Enterobacter amnigenus An11., PMID:23609231
Methotrexate induces germ cell apoptosis and impairs spermatogenesis in a rat., PMID:23224566
Brain region-specific altered expression and association of mitochondria-related genes in autism., PMID:23116158
The bacterium, Lysinibacillus sphaericus, as an insect pathogen., PMID:22137877
Lysinibacillus sphaericus S-layer protein toxicity against Culex quinquefasciatus., PMID:21671091
Chemically self-assembled antibody nanorings (CSANs): design and characterization of an anti-CD3 IgM biomimetic., PMID:21077608
Properties and applied use of the mosquitocidal bacterium, Bacillus sphaericus., PMID:28883761
Laetiporus sulphureus lectin and aerolysin protein family., PMID:20687481
Mesomelic dysplasia Kantaputra type is associated with duplications of the HOXD locus on chromosome 2q., PMID:20648051
Production and characterization of N- and C-terminally truncated Mtx2: a mosquitocidal toxin from Bacillus sphaericus., PMID:20411263
A new agent for tumour necrosis factor-alpha inhibition: In vitro effects of dipyridamole in Crohn's disease., PMID:19452347
For research use only. Not for human or drug use.
