Catalog No.
YHB16601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser77-Ser145
Predicted molecular weight
36.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75360
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Homeobox protein prophet of Pit-1, PROP-1, Pituitary-specific homeodomain factor, PROP1
Characterization of the recombination activity in the pituitary and ovary of Prop1-iCre knockin mice., PMID:40327412
Fertility induction associated with improved peripheral reproductive parameters in male Prop1df/df mice subjected to GH and levothyroxine replacement., PMID:39876974
Impact of visceral adipose tissue on longevity and metabolic health: a comparative study of gene expression in perirenal and epididymal fat of Ames dwarf mice., PMID:38517641
Comparison of clinical characteristics of a pediatric cohort with combined pituitary hormone deficiency caused by mutation of the PROP1 gene or of other origins., PMID:38147295
Association of Homozygous PROP1 Mutation in a Saudi Family with Combined Pituitary Hormone Deficiency., PMID:36984475
Analysis of ProP1 Gene in a Cohort of Tunisian Patients with Congenital Combined Pituitary Hormone Deficiency., PMID:36556141
Pituitary Tumors and Immortalized Cell Lines Generated by Cre-Inducible Expression of SV40 T Antigen., PMID:33837405
The effects of early-life growth hormone intervention on tissue specific histone H3 modifications in long-lived Ames dwarf mice., PMID:33378746
Hypopituitarism in five PROP1 mutation siblings: long-lasting natural course and the effects of growth hormone replacement introduction in middle adulthood., PMID:32415500
Mutations Within the Transcription Factor PROP1 in a Cohort of Turkish Patients with Combined Pituitary Hormone Deficiency., PMID:31948187
PROP1-Dependent Retinoic Acid Signaling Regulates Developmental Pituitary Morphogenesis and Hormone Expression., PMID:31913463
Genetic analysis of adult Slovenian patients with combined pituitary hormone deficiency., PMID:31093944
Combined pituitary hormone deficiency caused by PROP1 mutations: update 20 years post-discovery., PMID:31090814
Identification of a Novel PROP1 Mutation in a Patient with Combined Pituitary Hormone Deficiency and Enlarged Pituitary., PMID:30988269
Increased environmental temperature normalizes energy metabolism outputs between normal and Ames dwarf mice., PMID:30334813
Gene polymorphisms in PROP1 associated with growth traits in sheep., PMID:30316920
Screening a large pediatric cohort with GH deficiency for mutations in genes regulating pituitary development and GH secretion: Frequencies, phenotypes and growth outcomes., PMID:30266296
Regulation of Pituitary Progenitor Differentiation by β-Catenin., PMID:30085028
Retinoic acid signalling is a candidate regulator of the expression of pituitary-specific transcription factor Prop1 in the developing rodent pituitary., PMID:29356182
Genetic screening of regulatory regions of pituitary transcription factors in patients with idiopathic pituitary hormone deficiencies., PMID:29255988
Molecular analysis of brazilian patients with combined pituitary hormone deficiency and orthotopic posterior pituitary lobe reveals eight different PROP1 alterations with three novel mutations., PMID:28734020
Lessons from monogenic causes of growth hormone deficiency., PMID:28483366
Functionally enhanced brown adipose tissue in Ames dwarf mice., PMID:28452585
Combined pituitary hormone deficiency due to gross deletions in the POU1F1 (PIT-1) and PROP1 genes., PMID:28356564
Isolation of adult pituitary stem/progenitor cell clusters located in the parenchyma of the rat anterior lobe., PMID:27596959
Involvement of DNA methylation in regulating rat Prop1 gene expression during pituitary organogenesis., PMID:27773885
Identification of Novel PROP1 and POU1F1 Mutations in Patients with Combined Pituitary Hormone Deficiency., PMID:27756091
Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice., PMID:27740871
Regulation of pituitary stem cells by epithelial to mesenchymal transition events and signaling pathways., PMID:27650955
Identification of a novel progenitor cell marker, grainyhead-like 2 in the developing pituitary., PMID:27564454
Long-Term Outcomes, Genetics, and Pituitary Morphology in Patients with Isolated Growth Hormone Deficiency and Multiple Pituitary Hormone Deficiencies: A Single-Centre Experience of Four Decades of Growth Hormone Replacement., PMID:27487097
PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells., PMID:27351100
The expansion of adult stem/progenitor cells and their marker expression fluctuations are linked with pituitary plastic adaptation during gestation and lactancy., PMID:27302752
The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice., PMID:26973101
Cancerous leptomeningitis and familial congenital hypopituitarism., PMID:26886902
All Hormone-Producing Cell Types of the Pituitary Intermediate and Anterior Lobes Derive From Prop1-Expressing Progenitors., PMID:26812162
MECHANISMS IN ENDOCRINOLOGY: An update in the genetic aetiologies of combined pituitary hormone deficiency., PMID:26733480
Notch-Dependent Pituitary SOX2(+) Stem Cells Exhibit a Timed Functional Extinction in Regulation of the Postnatal Gland., PMID:26651607
Search for regulatory factors of the pituitary-specific transcription factor PROP1 gene., PMID:26640231
Expression studies of neuronatin in prenatal and postnatal rat pituitary., PMID:26613603
Two coexisting heterozygous frameshift mutations in PROP1 are responsible for a different phenotype of combined pituitary hormone deficiency., PMID:26608600
Polymorphism of Prophet of Pit-1 gene and its relationship with litter size of Small Tail Han sheep., PMID:26166199
Novel Mutations in HESX1 and PROP1 Genes in Combined Pituitary Hormone Deficiency., PMID:26111865
Genesis of two most prevalent PROP1 gene variants causing combined pituitary hormone deficiency in 21 populations., PMID:26059845
Dehydrated hereditary stomatocytosis masquerading as MDS., PMID:25927085
The c.301_302delAG PROP1 gene mutation in Romanian patients with multiple pituitary hormone deficiency., PMID:25581745
Molecular screening of a large cohort of Moroccan patients with congenital hypopituitarism., PMID:25557026
Molecular analysis of PROP1, POU1F1, LHX3, and HESX1 in Turkish patients with combined pituitary hormone deficiency: a multicenter study., PMID:25500790
Localization of juxtacrine factor ephrin-B2 in pituitary stem/progenitor cell niches throughout life., PMID:25480420
Circulating microRNA profiles and the identification of miR-593 and miR-511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency., PMID:25434367
For research use only. Not for human or drug use.
