Catalog No.
YHB03201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser357
Predicted molecular weight
41.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60884
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DnaJ homolog subfamily A member 2, Cell cycle progression restoration gene 3 protein, Dnj3, Dj3, HIRA-interacting protein 4, Renal carcinoma antigen NY-REN-14, DNAJA2, CPR3, HIRIP4
Polymorphism in Genes Encoding HSP40 Family Proteins is Associated with Ischemic Stroke Risk and Brain Infarct Size: A Pilot Study., PMID:39735968
The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations., PMID:39618332
Novel insights into the mechanisms of seasonal cyclicity of testicles by proteomics and transcriptomics analyses in goose breeder lines., PMID:39190991
DNAJA2 and Hero11 mediate similar conformational extension and aggregation suppression of TDP-43., PMID:39117455
Pseudophosphorylation of single residues of the J-domain of DNAJA2 regulates the holding/folding balance of the Hsc70 system., PMID:39012012
Evaluating protein prenylation of human and viral CaaX sequences using a humanized yeast system., PMID:38818856
A novel fatty acid metabolism-related signature identifies MUC4 as a novel therapy target for esophageal squamous cell carcinoma., PMID:38816411
Author Correction: The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70., PMID:38167402
Loss of Dja2 accompanies pH deviation in lysosomes and lysosome-related organelles., PMID:38108578
Integration of FUNDC1-associated mitochondrial protein import and mitochondrial quality control contributes to TDP-43 degradation., PMID:37951930
Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy., PMID:37907457
DnaJs are enriched in tau regulators., PMID:37852393
A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences., PMID:37786692
The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70., PMID:37670029
DNAJA2 deficiency activates cGAS-STING pathway via the induction of aberrant mitosis and chromosome instability., PMID:37640708
DnaJA2 interacts with Japanese encephalitis virus NS3 via its C-terminal to promote viral infection., PMID:37633595
Metamorphism in TDP-43 prion-like domain determines chaperone recognition., PMID:36709343
Histone acetyltransferase HAM1 interacts with molecular chaperone DNAJA2 and confers immune responses through salicylic acid biosynthetic genes in cassava., PMID:36451539
Structural resemblance of the DNAJA-family protein, Tid1, to the DNAJB-family Hsp40., PMID:35651334
Proteomic Profiling Differentiates Lymphoma Patients with and without Concurrent Myeloproliferative Neoplasia., PMID:34771688
Hsp40s play complementary roles in the prevention of tau amyloid formation., PMID:34369377
Oar-miR-16b and oar-miR-27a: negatively correlated with milk yield and milk protein in sheep., PMID:33840373
Evaluation of the Role of Human DNAJAs in the Response to Cytotoxic Chemotherapeutic Agents in a Yeast Model System., PMID:32149145
Selective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR., PMID:32144307
Hsp70 and DNAJA2 limit CFTR levels through degradation., PMID:31408507
Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor., PMID:31395886
A cytosolic chaperone complex controls folding and degradation of type III CD38., PMID:30670591
DnaJ chaperones contribute to canalization., PMID:30653842
Mapping interactions with the chaperone network reveals factors that protect against tau aggregation., PMID:29728653
High-throughput screen for inhibitors of protein-protein interactions in a reconstituted heat shock protein 70 (Hsp70) complex., PMID:29414793
In vitro reconstitution of chaperone-mediated human RISC assembly., PMID:28971854
miR-155-3p Drives the Development of Autoimmune Demyelination by Regulation of Heat Shock Protein 40., PMID:26674874
Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro., PMID:24318877
Formation of chimeric genes by copy-number variation as a mutational mechanism in schizophrenia., PMID:24094746
Human Hsp40 proteins, DNAJA1 and DNAJA2, as potential targets of the immune response triggered by bacterial DnaJ in rheumatoid arthritis., PMID:23408083
The DNAJA2 substrate release mechanism is essential for chaperone-mediated folding., PMID:23091061
Effect of dental amalgam on gene expression profiles in rat cerebrum, cerebellum, liver and kidney., PMID:22688007
Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1., PMID:22085931
Channel triage: Emerging insights into the processing and quality control of hERG potassium channels by DnaJA proteins 1, 2 and 4., PMID:20699637
Hsp40 chaperones promote degradation of the HERG potassium channel., PMID:19940115
RDJ2 (DNAJA2) chaperones neural G protein signaling pathways., PMID:18595009
Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome., PMID:18515302
Identification of differentially expressed ovarian genes during primary and early secondary oocyte growth in coho salmon, Oncorhynchus kisutch., PMID:18205936
Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci., PMID:17242198
Rdj2, a J protein family member, interacts with cellular prion PrP(C)., PMID:16774738
Ischemic preconditioning prevents protein aggregation after transient cerebral ischemia., PMID:15939539
A type I DnaJ homolog, DjA1, regulates androgen receptor signaling and spermatogenesis., PMID:15660130
High resolution mapping of an arthritis susceptibility locus on rat chromosome 4, and characterization of regulated phenotypes., PMID:12915467
Characterization and functional analysis of a heart-enriched DnaJ/ Hsp40 homolog dj4/DjA4., PMID:12380683
Identification of two estrogen regulated genes associated with growth regulation of human breast cancer., PMID:11500233
For research use only. Not for human or drug use.
