Catalog No.
YHA83601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu364-Glu746
Predicted molecular weight
44.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60231
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16, 3.6.4.13, ATP-dependent RNA helicase #3, DEAH-box protein 16, DHX16, DBP2, DDX16, KIAA0577, PRP2
fmd/fmd2/DHX16-dsx cascade in sex determination of one Hemiptera species, Laodelphax striatellus., PMID:40329630
DHX16-Associated Neuromuscular Oculoauditory Syndrome: A Novel Case., PMID:40326698
Rare Case with Pathogenic Variant in DHX16 Gene Causing Neuromuscular Disease and Oculomotor Anomalies., PMID:40141454
Essential role of Dhx16-mediated ribosome assembly in maintenance of hematopoietic stem cells., PMID:39333759
Expansion of the phenotypic spectrum associated with pathogenic missense variation in DHX16., PMID:37664979
Infantile onset encephalomyopathy, retinopathy, optic atrophy, and mitochondrial DNA depletion associated with a novel pathogenic DHX16 variant., PMID:37574199
Comprehensively analysis of splicing factors to construct prognosis prediction classifier in prostate cancer., PMID:37559353
Heterozygous loss-of-function DHX9 variants are associated with neurodevelopmental disorders: Human genetic and experimental evidences., PMID:37369308
Structural basis of catalytic activation in human splicing., PMID:37165190
Systematic analysis of the BET family in adrenocortical carcinoma: The expression, prognosis, gene regulation network, and regulation targets., PMID:36793283
African-specific molecular taxonomy of prostate cancer., PMID:36045292
Rare Variant Analysis and Molecular Dynamics Simulation in Alzheimer's Disease Identifies Exonic Variants in FLG., PMID:35627223
The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity., PMID:35263596
Pan-Cancer Analysis Reveals Alternative Splicing Characteristics Associated With Immune-Related Adverse Events Elicited by Checkpoint Immunotherapy., PMID:34899357
ZNF76 predicts prognosis and response to platinum chemotherapy in human ovarian cancer., PMID:34793589
The RGG domain in the C-terminus of the DEAD box helicases Dbp2 and Ded1 is necessary for G-quadruplex destabilization., PMID:34302476
Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs., PMID:32141009
Light at Night Exposure Effects on Differentiation and Cell Cycle in the Rat Liver With Autonomic Nervous System Denervation., PMID:32021672
Paralog Studies Augment Gene Discovery: DDX and DHX Genes., PMID:31256877
Promoter architecture determines cotranslational regulation of mRNA., PMID:29567675
GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo., PMID:25296192
Dynamic protein-protein interaction wiring of the human spliceosome., PMID:22365833
The zebrafish maternal-effect gene mission impossible encodes the DEAH-box helicase Dhx16 and is essential for the expression of downstream endodermal genes., PMID:21396359
Nuclear retention of unspliced pre-mRNAs by mutant DHX16/hPRP2, a spliceosomal DEAH-box protein., PMID:20841358
Contribution of DEAH-box protein DHX16 in human pre-mRNA splicing., PMID:20423332
For research use only. Not for human or drug use.
