Catalog No.
YHA73701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Trp194-Phe514
Predicted molecular weight
38.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43660
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Pleiotropic regulator 1, PLRG1
YBX1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma via transcriptional regulation of PLRG1., PMID:39400789
Association of major candidate protein biomarkers and long-term diabetic kidney disease progression among Asians with young-onset type 2 diabetes mellitus., PMID:39142520
Elevated level of PLRG1 is critical for the proliferation and maintenance of genome stability of tumor cells., PMID:37817442
Investigation on the cellular mechanism of Prunetin evidenced through next generation sequencing and bioinformatic approaches against gastric cancer., PMID:35831348
RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1., PMID:35290436
USP42 drives nuclear speckle mRNA splicing via directing dynamic phase separation to promote tumorigenesis., PMID:33731873
Crystal structure of the WD40 domain of human PLRG1., PMID:33239170
Leucine-rich α2-glycoprotein-1 upregulation in plasma and kidney of patients with lupus nephritis., PMID:32252660
Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors., PMID:29547724
The PSO4 protein complex associates with replication protein A (RPA) and modulates the activation of ataxia telangiectasia-mutated and Rad3-related (ATR)., PMID:24443570
BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing., PMID:23249746
Serum organochlorine pesticide residues and risk of gallstone disease: a case-control study in Xiamen., PMID:22695391
Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice., PMID:20467437
Identification of pancreatic juice proteins as biomarkers of pancreatic cancer., PMID:20428826
The Pso4 complex splices into the DNA damage response., PMID:19838058
Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint., PMID:19633697
PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis., PMID:19307306
The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage., PMID:17276391
The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links., PMID:16223718
Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1., PMID:14576297
A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing., PMID:11544257
For research use only. Not for human or drug use.
