Catalog No.
YHA71701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Cys259
Predicted molecular weight
32.67 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43586
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Proline-serine-threonine phosphatase-interacting protein 1, PEST phosphatase-interacting protein 1, CD2-binding protein 1, H-PIP, PSTPIP1, CD2BP1
A Systematic Review of Mendelian Pyoderma Gangrenosum: Clinical and Genetic Characteristics in 120 Published Patients., PMID:40329681
Serum interleukin-18 levels are specifically elevated in auto-inflammatory diseases involving the pyrin inflammasome: A study on 516 patients., PMID:40204564
[Autoinflammatory diseases associated with IL-18]., PMID:39155178
PSTPIP1-associated myeloid-related proteinemia inflammatory (PAMI) syndrome: A case report and review of the literature., PMID:38967953
Stimulation of PSTPIP1 to trigger proinflammatory responses in asymptomatic SARS-CoV-2 infections., PMID:38463809
Interrupting an IFN-γ-dependent feedback loop in the syndrome of pyogenic arthritis with pyoderma gangrenosum and acne., PMID:38408849
Efficacy and safety of anakinra and canakinumab in PSTPIP1-associated inflammatory diseases: a comprehensive scoping review., PMID:38259483
Histone deacetylase-mediated silencing of PSTPIP2 expression contributes to aristolochic acid nephropathy-induced PANoptosis., PMID:38073114
PAPA Syndrome: Challenges in Achieving Long-Term Remission., PMID:38006373
Selective Sweeps in Cattle Genomes in Response to the Influence of Urbanization and Environmental Contamination., PMID:38003026
AA amyloidosis in a father and daughter as complication of PSTPIP1-associated myeloid-related proteinemia inflammatory (PAMI) syndrome., PMID:37870967
PSTPIP1-Associated Myeloid-Related Proteinemia Inflammatory (PAMI) Syndrome: A Systematic Review., PMID:37628706
Rare missense variants in the SH3 domain of PSTPIP1 are associated with hidradenitis suppurativa., PMID:37013170
Comment on: Detection of a rare variant in PSTPIP1 through three generations in a family with an initial diagnosis of FMF/MKD-overlapping phenotype., PMID:36864619
N-BAR and F-BAR proteins-endophilin-A3 and PSTPIP1-control clathrin-independent endocytosis of L1CAM., PMID:36843549
Detection of a rare variant in PSTPIP1 through three generations in a family with an initial diagnosis of FMF/MKD-overlapping phenotype., PMID:36692132
Renal involvement as a potential feature of pyogenic arthritis, pyoderma gangrenosum, and acne syndrome with E250K mutation of PSTPIP1 gene., PMID:36660269
Pan-Cancer Analysis Identifies Tumor Cell Surface Targets for CAR-T Cell Therapies and Antibody Drug Conjugates., PMID:36428765
Strong inflammatory signatures in the neutrophils of PAMI syndrome., PMID:36203570
Immune-mediated inflammatory diseases with chronic excess of serum interleukin-18., PMID:35958573
PSTPIP1-associated myeloid-related proteinaemia inflammatory (PAMI) syndrome; a case presenting as a perinatal event with early central nervous system involvement?, PMID:35840971
Identification of Novel Prognostic Biomarkers Relevant to Immune Infiltration in Lung Adenocarcinoma., PMID:35571056
Clinical and Genetic Features of Chinese Adult Patients With Chronic Non-Bacterial Osteomyelitis: A Single Center Report., PMID:35422809
Variants in autoinflammatory diseases-related genes in a family with cold-induced autoinflammatory syndrome., PMID:35383566
PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders., PMID:35152348
Clinical and Genetic Findings of the First Report of PAPA Syndrome in Brazil., PMID:34938582
The PRY/SPRY domain of pyrin/TRIM20 interacts with β2-microglobulin to promote inflammasome formation., PMID:34880353
Kidney Involvement in PSTPIP1 Associated Inflammatory Diseases (PAID): A Case Report and Review of the Literature., PMID:34778321
Mutation in the proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1) gene in a patient with acute lymphoblastic leukemia., PMID:34764798
Case Report: Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne: A Single-Center Experience and Literature Review., PMID:34745107
Clinical and genetic characteristics of PSTPIP1-associated myeloid-related proteinemia inflammatory syndrome., PMID:34620178
Analysis of five cases of monogenic lupus related to primary immunodeficiency diseases., PMID:34559261
Excess Serum Interleukin-18 Distinguishes Patients With Pathogenic Mutations in PSTPIP1., PMID:34492165
Immunological repertoire linked to PSTPIP1-associated myeloid-related inflammatory (PAMI) syndrome., PMID:34399798
Severe ulcerative proctitis, pyoderma gangrenosum, hidradenitis suppurativa and fever in a patient with a rare variant of the PSTPIP1 gene., PMID:34273117
PAMI syndrome: A rare cause that can be easily misdiagnosed., PMID:34047005
Hemolysis and Neurologic Impairment in PAMI Syndrome: Novel Characteristics of an Elusive Disease., PMID:33597285
A case of PAPASH syndrome in a young man carrying a novel heterozygote missense variant in PSTPIP1., PMID:33587775
A case of myeloperoxidase-antineutrophil cytoplasmic antibody and anticardiolipin antibody-positive pyogenic arthritis, pyoderma gangrenosum, acne and hidradenitis suppurativa (PAPASH) syndrome with colitis., PMID:33560194
Genetic variations in gamma-secretase and PSTPIP1 in hidradenitis suppurativa in Singaporean Chinese., PMID:33460495
Rare cases of PAMI syndrome in both father and son with the same missense mutation in PSTPIP1 gene and literature review., PMID:33458872
HSCT is effective in patients with PSTPIP1-associated myeloid-related proteinemia inflammatory (PAMI) syndrome., PMID:33338535
Ancient friends, revisited: Systematic review and case report of pyoderma gangrenosum-associated autoinflammatory syndromes., PMID:33305249
Colchicine-Induced Macrophage Activation Syndrome in an Adolescent Female Patient With PSTPIP1-Associated Myeloid-Related Proteinemia Inflammatory Syndrome., PMID:33295717
[Targeted therapy of pyogenic sterile arthritis, pyoderma gangrenosum, and acne syndrome (PAPA): a case report and literature review]., PMID:33256319
Phenotypic Associations of PSTPIP1 Sequence Variants in PSTPIP1-Associated Autoinflammatory Diseases., PMID:33218716
Hidradenitis Suppurativa: Proposal of Classification in Two Endotypes with Two-Step Cluster Analysis., PMID:33171462
Additive Effects of Zinc Chloride on the Suppression of Hepatitis A Virus Replication by Interferon in Human Hepatoma Huh7 Cells., PMID:33144437
Quantitative proteomics revealed modulation of macrophages by MetQ gene of Streptococcus suis serotype 2., PMID:33125582
National external quality assessment for next-generation sequencing-based diagnostics of primary immunodeficiencies., PMID:32733070