Catalog No.
YHA70401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His40-Cys280
Predicted molecular weight
29.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43543
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DNA repair protein XRCC2, X-ray repair cross-complementing protein 2, XRCC2
Relationship between autoimmunity and COPD: an investigation based on proteomic profiling and antinuclear antibody screening., PMID:40329569
Genetic Polymorphisms of DNA Repair Genes and their Influence on Paclitaxel based Chemotherapy Induced Toxicity Reactions in Breast Cancer Patients., PMID:39733420
Discovery of novel xanthohumol C derivatives regulating XRCC2 transcription and expression for the treatment of colorectal cancer., PMID:39731930
Somatic gene mutations involved in DNA damage response/Fanconi anemia signaling are tissue- and cell-type specific in human solid tumors., PMID:39421870
FIGL1 attenuates meiotic interhomolog repair and is counteracted by the RAD51 paralog XRCC2 and the chromosome axis protein ASY1 during meiosis., PMID:39420761
RAD51 Paralogs and RAD51 Paralog Complexes BCDX2 and CX3 Interact with BRCA2., PMID:39416194
The role of RAD51 regulators and variants in primary ovarian insufficiency, endometriosis, and polycystic ovary syndrome., PMID:39359934
Mechanism of BCDX2-mediated RAD51 nucleation on short ssDNA stretches and fork DNA., PMID:39268578
Identifying crucial lncRNAs and mRNAs in hypoxia-induced A549 lung cancer cells and investigating their underlying mechanisms via high-throughput sequencing., PMID:39236027
Targeting proliferating cell nuclear antigen enhances ionizing radiation-induced cytotoxicity in prostate cancer cells., PMID:39219052
Screening of gastric cancer diagnostic biomarkers in the homologous recombination signaling pathway and assessment of their clinical and radiomic correlations., PMID:39206620
c-Myc-XRCC2-FOS axis promotes the proliferation and the resistance to Doxorubicin of NSCLC., PMID:39153434
Anti-inflammatory and DNA Repair Effects of Astragaloside IV on PC12 Cells Damaged by Lipopolysaccharide., PMID:39112916
Association of XRCC2 with breast cancer, a multi-omics analysis at genomic, transcriptomic, and epigenomic level., PMID:39097872
XRCC2 driven homologous recombination subtypes and therapeutic targeting in lung adenocarcinoma metastasis., PMID:39090304
XRCC2 knockdown effectively sensitizes esophageal cancer to albumin-paclitaxel in vitro and in vivo., PMID:39048769
Clinico-genomic findings, molecular docking, and mutational spectrum in an understudied population with breast cancer patients from KP, Pakistan., PMID:38784039
Possible New Candidates Involved to Thalidomide-Related Limbs and Cardiac Defects: A Systems Biology Approach., PMID:38689186
Unraveling the genetics of arsenic toxicity with cellular morphology QTL., PMID:38662777
Interaction between XRCC2 gene polymorphism and abdominal obesity on risk of endometrial carcinoma., PMID:38518807
RNA helicase DDX3 regulates RAD51 localization and DNA damage repair in Ewing sarcoma., PMID:38323009
Association between XRCC2 Arg188His Polymorphism and Breast Cancer Susceptibility: A Systematic Review and Meta-Analysis., PMID:38285766
Exploring homologous recombination repair and base excision repair pathway genes for possible diagnostic markers in hematologic malignancies., PMID:37861816
RAD51 paralogs synergize with RAD51 to protect reversed forks from cellular nucleases., PMID:37843130
Impact of Interaction between Single Nucleotide Polymorphism of XRCC1, XRCC2, XRCC3 with Tumor Suppressor Tp53 Gene Increases Risk of Breast Cancer: A Hospital Based Case-Control Study., PMID:37774058
Single Nucleotide Polymorphisms in DNA Repair Genes (XRCC1, XRCC2, XRCC3) and Their Association with Radiotherapy Toxicity among Head and Neck Cancer Patients:A Study from South-Western Maharashtra., PMID:37774056
Germline Sequencing Analysis to Inform Clinical Gene Panel Testing for Aggressive Prostate Cancer., PMID:37733366
Association of RAD51, XRCC1, XRCC2, and XRCC3 Polymorphisms with Risk of Breast Cancer., PMID:37522793
Structural insights into BCDX2 complex function in homologous recombination., PMID:37344589
Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor., PMID:37344587
RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma., PMID:37333164
Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C., PMID:37253112
Postnatal nutrition environment reprograms renal DNA methylation patterns in offspring of maternal protein-restricted stroke-prone spontaneously hypertensive rats., PMID:37125041
Differential expression of DNA repair genes and treatment outcome of chemoradiotherapy (CRT) in cervical cancer., PMID:36963733
Evaluation of AlphaFold structure-based protein stability prediction on missense variations in cancer., PMID:36896237
Systematic proximal mapping of the classical RAD51 paralogs unravel functionally and clinically relevant interactors for genome stability., PMID:36374936
Identification of Prognostic Markers and Potential Therapeutic Targets in Gastric Adenocarcinoma by Machine Learning Based on mRNAsi Index., PMID:36213825
Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants., PMID:36099300
Understanding Role of DNA Repair and Cytochrome p-450 Gene Polymorphisms in Cervical Cancer Patient Treated With Concomitant Chemoradiation., PMID:35996502
Strand annealing and motor driven activities of SMARCAL1 and ZRANB3 are stimulated by RAD51 and the paralog complex., PMID:35801922
Pathogenicity Reclassification of Genetic Variants Related to Early-Onset Breast Cancer among Women of Mongoloid Origin., PMID:35763645
The interplay between XPG-Asp1104His polymorphism and reproductive risk factors elevates risk of breast cancer in Tanzanian women: A multiple interaction analysis., PMID:35691022
PARP inhibitor olaparib enhances the efficacy of radiotherapy on XRCC2-deficient colorectal cancer cells., PMID:35643812
Further refining 2020 ESGO/ESTRO/ESP molecular risk classes in patients with early-stage endometrial cancer: A propensity score-matched analysis., PMID:35617463
A review on the genetic polymorphisms and susceptibility of cancer patients in Bangladesh., PMID:35277785
Homologous recombination DNA repair gene RAD51, XRCC2 & XRCC3 polymorphisms and breast cancer risk in South Indian women., PMID:35061678
Genetics of ovarian insufficiency and defects of folliculogenesis., PMID:34794894
XRCC2 Arg188His polymorphism and colorectal cancer risk: a meta-analysis., PMID:34648414
Comprehensive Analysis of Prognostic and Immune Infiltrates for RAD51 in Human Breast Cancer., PMID:34587437
A comprehensive molecular study identified 12 complementation groups with 56 novel FANC gene variants in Indian Fanconi anemia subjects., PMID:34585473
For research use only. Not for human or drug use.
