Catalog No.
YHA69401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Pro233
Predicted molecular weight
29.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43513
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mediator of RNA polymerase II transcription subunit 7, hMED7, Activator-recruited cofactor 34 kDa component, ARC34, Cofactor required for Sp1 transcriptional activation subunit 9, CRSP complex subunit 9, Mediator complex subunit 7, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33, MED7, ARC34, CRSP9
Baicalein Inhibits Tumor Property of Hepatocellular Carcinoma Cells Through the Inactivation of the E2F Transcription Factor 1/Mediator Complex Subunit 7 Axis., PMID:39935236
Systematic analysis of the expression profiles and prognostic significance of the MED gene family in renal clear cell carcinoma., PMID:38979551
Upregulation of MED7 was associated with progression in hepatocellular carcinoma., PMID:38073375
NLRs derepress MED10b- and MED7-mediated repression of jasmonate-dependent transcription to activate immunity., PMID:37399403
Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer., PMID:31558802
The MED7 subunit paralogs of Mediator function redundantly in development of etiolated seedlings in Arabidopsis., PMID:30058106
Mediator complex (MED) 7: a biomarker associated with good prognosis in invasive breast cancer, especially ER+ luminal subtypes., PMID:29588513
ScMED7, a sugarcane mediator subunit gene, acts as a regulator of plant immunity and is responsive to diverse stress and hormone treatments., PMID:28785867
Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme., PMID:27821593
A functional portrait of Med7 and the mediator complex in Candida albicans., PMID:25375174
Characterization of the influence of mediator complex in HIV-1 transcription., PMID:25100719
Model of the Mediator middle module based on protein cross-linking., PMID:23939621
MC EMiNEM maps the interaction landscape of the Mediator., PMID:22737066
Role of Mediator in regulating Pol II elongation and nucleosome displacement in Saccharomyces cerevisiae., PMID:22377631
Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization., PMID:21498544
Mediator influences telomeric silencing and cellular life span., PMID:21482672
Preparation and topology of the Mediator middle module., PMID:20123732
Malleable machines in transcription regulation: the mediator complex., PMID:19096501
Saccharomyces cerevisiae Med9 comprises two functionally distinct domains that play different roles in transcriptional regulation., PMID:19077037
Identification, structure, and functional requirement of the Mediator submodule Med7N/31., PMID:19057509
MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling., PMID:18391015
Specific defects in different transcription complexes compensate for the requirement of the negative cofactor 2 repressor in Saccharomyces cerevisiae., PMID:17339209
A kinase subunit of the human mediator complex, CDK8, positively regulates transcriptional activation., PMID:17212659
The classical srb4-138 mutant allele causes dissociation of yeast Mediator., PMID:16962561
Functional and physical interactions within the middle domain of the yeast mediator., PMID:16758199
A functional module of yeast mediator that governs the dynamic range of heat-shock gene expression., PMID:16452140
The Sp transcription factors are involved in the cellular expression of the human glucose-dependent insulinotropic polypeptide receptor gene and overexpressed in adrenals of patients with Cushing's syndrome., PMID:16087722
A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer., PMID:15710619
The Sp transcription factor family is involved in the cellular expression of the human GIP-R gene promoter., PMID:15666829
Quantitative analysis of binding of transcription factor complex to biotinylated DNA probe by a streptavidin-agarose pulldown assay., PMID:14622953
The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans., PMID:11728440
Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe., PMID:10625684
Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation., PMID:10611325
Transcription: Common cofactors and cooperative recruitment., PMID:10469586
The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1., PMID:9989412
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways., PMID:9671713
The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain., PMID:9420330
For research use only. Not for human or drug use.
