Catalog No.
YHA48301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly341-Leu622
Predicted molecular weight
33.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15287
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fanconi anemia group G protein, Protein FACG, DNA repair protein XRCC9, FANCG, XRCC9
Clinicopathologic and molecular characterization of primitive neuroectodermal tumors (PNET) in the female genital tract: a retrospective study of 8 cases., PMID:40189027
The combination of poly(ADP-ribose) polymerase inhibitor and statin inhibits the proliferation of human castration-resistant and taxane-resistant prostate cancer cells in vitro and in vivo., PMID:40119293
Novel De Novo BRCA2 Variant in an Early-Onset Ovarian Cancer Reveals a Unique Tumor Evolution Pathway., PMID:40076915
Polyphenols from the husk of T. acornis suppresses MDA-MB-231 cells growth via Fanconi Anemia pathway., PMID:39955011
Protein subinteractomes of human microsomal cytochromes P450., PMID:39937310
Prognostic significance of mutation type and chromosome fragility in Fanconi anemia., PMID:39562502
Chemical Carcinogen (3-Methylcholanthrene)-induced Pleomorphic Rhabdomyosarcomas in Fanconi Anemia Fancd2-/-, Fancg-/- (C57BL/6), Fancd2-/- (129/Sv) Mice., PMID:39477388
A comprehensive study evaluating germline FANCG variants in predisposition to breast and ovarian cancer., PMID:39149814
[Mechanisms of the Effect of Maternal Age-Related Oocyte Aging on Fertility: Transcriptomic Sequencing Analysis of a Zebrafish Model]., PMID:38948296
Clinical actionability of BRCA2 alterations in uterine leiomyosarcoma: a molecular tumor board case report and a cBioPortal comprehensive analysis., PMID:38716772
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice., PMID:38447038
Uncovering the clinical relevance of unclassified variants in DNA repair genes: a focus on BRCA negative Tunisian cancer families., PMID:38313678
DNA damage response and repair gene mutations are associated with tumor mutational burden and outcomes to platinum-based chemotherapy/immunotherapy in advanced NSCLC patients., PMID:37924135
A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype., PMID:37446306
Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutations., PMID:36604691
Genetic analysis of a Fanconi anemia case revealed the presence of FANCF mutation (exon 1;469>C-T) with implications to develop acute myeloid leukemia., PMID:36369330
Distinct clinicopathological characteristics, genomic alteration and prognosis in breast cancer with concurrent TP53 mutation and MYC amplification., PMID:36305094
Identification of a Hypomorphic FANCG Variant in Bernese Mountain Dogs., PMID:36292578
Exploring the molecular and functional cellular response to hydrazine via transcriptomics and DNA repair mutant cell lines., PMID:36176055
Fanconi Anemia Patients from an Indigenous Community in Mexico Carry a New Founder Pathogenic Variant in FANCG., PMID:35216452
Can the Synergic Contribution of Multigenic Variants Explain the Clinical and Cellular Phenotypes of a Neurodevelopmental Disorder?, PMID:35052418
In silico study of missense variants of FANCA, FANCC and FANCG genes reveals high risk deleterious alleles predisposing to Fanconi anemia pathogenesis., PMID:34864095
Germline variants in DNA repair genes are associated with young-onset head and neck cancer., PMID:34598035
Loss of FANCD2 and related proteins may predict malignant transformation in oral epithelial dysplasia., PMID:34493474
Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation., PMID:34436527
Clinical, cytogenetic and molecular findings in nine Moroccan patients with Fanconi anemia., PMID:34422195
Abnormal migration behavior linked to Rac1 signaling contributes to primordial germ cell exhaustion in Fanconi anemia pathway-deficient Fancg-/- embryos., PMID:34368842
Promyelocytic Leukemia Proteins Regulate Fanconi Anemia Gene Expression., PMID:34360546
Clinicopathological and molecular characterization of chromophobe hepatocellular carcinoma., PMID:34036718
The causes of Fanconi anemia in South Asia and the Middle East: A case series and review of the literature., PMID:33960719
Nitric oxide synthase-2 (NOS2) gene polymorphism c.1832C>T (Ser608Leu) associated with nitrosative stress in Fanconi anaemia., PMID:33778919
Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management., PMID:33445068
Severe telomere shortening in Fanconi anemia complementation group L., PMID:33394227
Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2., PMID:33069004
Loss of Mitochondrial Localization of Human FANCG Causes Defective FANCJ Helicase., PMID:32989015
Clinical and Genetic Features of Patients With Fanconi Anemia in Lebanon and Report on Novel Mutations in the FANCA and FANCG Genes., PMID:32947577
The identification of six risk genes for ovarian cancer platinum response based on global network algorithm and verification analysis., PMID:32762026
Endocrine profiling in patients with Fanconi anemia, homozygous for a FANCG founder mutation., PMID:32529760
[Molecular predictors for the course of disease and individualized therapy in pancreatic cancer]., PMID:32405728
Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex., PMID:32002546
Fanconi Anemia Mouse Genotype-specific Mitigation of Total Body Irradiation by GS-Nitroxide JP4-039., PMID:31882460
Single-Molecule Sequencing: A New Approach for Preimplantation Testing and Noninvasive Prenatal Diagnosis Confirmation of Fetal Genotype., PMID:31751677
Characterization and genotype-phenotype correlation of patients with Fanconi anemia in a multi-ethnic population., PMID:31558676
Enhanced DNA repair and genomic stability identify a novel HIV-related diffuse large B-cell lymphoma signature., PMID:31044434
Analysis of polymorphisms in genes associated with the FA/BRCA pathway in three patients with multiple primary malignant neoplasms., PMID:30942098
Bone marrow niches of germline FANCC/FANCG deficient mice enable efficient and durable engraftment of hematopoietic stem cells after transplantation., PMID:30679321
Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility., PMID:30540754
Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia., PMID:30449320
The identification of pathogenic variants in BRCA1/2 negative, high risk, hereditary breast and/or ovarian cancer patients: High frequency of FANCM pathogenic variants., PMID:30426508
For research use only. Not for human or drug use.
