Catalog No.
YHA44801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu73-Gln410
Predicted molecular weight
40.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15204
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADAM DEC1, 3.4.24.-, A disintegrin and metalloproteinase domain-like protein decysin-1, ADAM-like protein decysin-1, ADAMDEC1
Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes., PMID:40032993
ADAMDEC1 promotes the malignant progression of cholangiocarcinoma by regulating NF-κB signaling pathway., PMID:39755752
ADAMDEC1 promotes cervical squamous cell carcinoma by enhancing the JAK/STAT signaling pathway through modulation of TYMP., PMID:39625490
Guanylate binding protein 5 is an immune-related biomarker of oral squamous cell carcinoma: A retrospective prognostic study with bioinformatic analysis., PMID:38978333
Single-cell RNA sequencing reveals cellular dynamics and therapeutic effects of astragaloside IV in slow transit constipation., PMID:38289380
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression., PMID:38063920
An immune signature to predict the prognosis of ATRX-wildtype glioma patients and guide immune checkpoint blockade therapy., PMID:37812190
Bioinformatics analysis of PLA2G7 as an immune-related biomarker in COPD by promoting expansion and suppressive functions of MDSCs., PMID:37270927
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β., PMID:37187249
Changes in DNA methylation profile in liver tissue during progression of HCV-induced fibrosis to hepatocellular carcinoma., PMID:36923478
ADAMDEC1 accelerates GBM progression via activation of the MMP2-related pathway., PMID:36172139
Analysis of melanoma tumor antigens and immune subtypes for the development of mRNA vaccine., PMID:35962880
Hub genes associated with immune cell infiltration in breast cancer, identified through bioinformatic analyses of multiple datasets., PMID:35819135
Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα+ Cells Is a New Marker for Inflammatory Bowel Disease., PMID:35563399
Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers., PMID:35560163
Potential biomarkers that discriminate rheumatoid arthritis and osteoarthritis based on the analysis and validation of datasets., PMID:35379209
Upregulation of ADAMDEC1 correlates with tumor progression and predicts poor prognosis in non-small cell lung cancer (NSCLC) via the PI3K/AKT pathway., PMID:35178875
Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing., PMID:35085231
Immune landscape of advanced gastric cancer tumor microenvironment identifies immunotherapeutic relevant gene signature., PMID:34893046
Immune marker signature helps to predict survival in uveal melanoma., PMID:34198425
Biological potentials for a family of disintegrin and metalloproteinase (ADAMDEC)-1 in mouse normal pregnancy., PMID:33612551
Knockdown of ADAMDEC1 inhibits the progression of glioma in vitro., PMID:32378728
ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells., PMID:31993498
ADAMDEC1 promotes skin inflammation in rosacea via modulating the polarization of M1 macrophages., PMID:31627897
Potential early clinical stage colorectal cancer diagnosis using a proteomics blood test panel., PMID:31467500
ADAMDEC1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells., PMID:31434712
FcγRIIb on B Cells and Myeloid Cells Modulates B Cell Activation and Autoantibody Responses via Different but Synergistic Pathways in Lupus-Prone Yaa Mice., PMID:30373853
Enhancer RNA and NFκB-dependent P300 regulation of ADAMDEC1., PMID:30352365
Identification of differentially expressed genes in synovial tissue of rheumatoid arthritis and osteoarthritis in patients., PMID:30260019
Epstein-Barr Virus Nuclear Antigen 3C Inhibits Expression of COBLL1 and the ADAM28-ADAMDEC1 Locus via Interaction with the Histone Lysine Demethylase KDM2B., PMID:30135119
ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells., PMID:29941981
The role of ADAM-like decysin 1 in non-eosinophilic chronic rhinosinusitis with nasal polyps., PMID:29936897
ADAM9 is over-expressed in human ovarian clear cell carcinomas and suppresses cisplatin-induced cell death., PMID:29247567
Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma., PMID:29185848
Review: The transcripts associated with organ allograft rejection., PMID:29178397
Adamdec1, Ednrb and Ptgs1/Cox1, inflammation genes upregulated in the intestinal mucosa of obese rats, are downregulated by three probiotic strains., PMID:28512356
The soluble protease ADAMDEC1 released from activated platelets hydrolyzes platelet membrane pro-epidermal growth factor (EGF) to active high-molecular-weight EGF., PMID:28455445
Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation., PMID:27226416
EBNA3C Directs Recruitment of RBPJ (CBF1) to Chromatin during the Process of Gene Repression in EBV Infected B Cells., PMID:26751214
Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors., PMID:25564618
Molecular landscape of T cell-mediated rejection in human kidney transplants: prominence of CTLA4 and PD ligands., PMID:25219326
Proteomic analysis of human osteoarthritis synovial fluid., PMID:24533825
Infliximab restores the dysfunctional matrix remodeling protein and growth factor gene expression in patients with inflammatory bowel disease., PMID:24378596
A gene expression profile related to immune dampening in the tumor microenvironment is associated with poor prognosis in gastric adenocarcinoma., PMID:24217965
Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming., PMID:24068937
ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity., PMID:23754285
Early dynamic transcriptomic changes during preoperative radiotherapy in patients with rectal cancer: a feasibility study., PMID:23745026
Gene biomarkers in peripheral white blood cells of horses with experimentally induced osteoarthritis., PMID:23270355
Expression and inhibition of ADAMDEC1 in craniopharyngioma cells., PMID:22776555
Downregulation of integrin receptor-signaling genes by Epstein-Barr virus EBNA 3C via promoter-proximal and -distal binding elements., PMID:22357270
For research use only. Not for human or drug use.
