Catalog No.
YHA44601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly368-Leu580
Predicted molecular weight
25.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15197
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ephrin type-B receptor 6, HEP, Tyrosine-protein kinase-defective receptor EPH-6, EPHB6
Cracking the Kinase Code: Urinary Biomarkers as Early Alarms for AAA Rupture-A Pilot Study., PMID:40507607
Development of a novel anti-erythropoietin-producing hepatocellular receptor B6 monoclonal antibody Eb6Mab-3 for flow cytometry., PMID:40065768
Establishing a prognostic model with immune-related genes and investigating EPHB6 expression pattern in breast cancer., PMID:39994456
Transcriptome Profiling Associated with CARD11 Overexpression in Colorectal Cancer Implicates a Potential Role for Tumor Immune Microenvironment and Cancer Pathways Modulation via NF-κB., PMID:39408697
Genomic Study of Taste Perception Genes in African Americans Reveals SNPs Linked to Alzheimer's Disease., PMID:39372803
Study on the Role of EPHB6 in Inhibiting the Malignant Progression of Cervical Cancer C33A Cells by Binding to CBX7., PMID:39322790
Genomic study of taste perception genes in African Americans reveals SNPs linked to Alzheimer's disease., PMID:39284855
Genetic Features of Tongue Cancer Recurrence in Young Adults., PMID:39127975
Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion., PMID:38627519
Erythropoietin-producing hepatocellular receptor B6 is highly expressed in non-functioning pituitary neuroendocrine tumors and its expression correlates with tumor size., PMID:38341842
Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome., PMID:37587118
Oat beta-glucan reduces colitis by promoting autophagy flux in intestinal epithelial cells via EPHB6-TFEB axis., PMID:37441529
Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR., PMID:37392382
A splicing transcriptome-wide association study identifies novel altered splicing for Alzheimer's disease susceptibility., PMID:37354922
EphB6 deficiency in intestinal neurons promotes tumor growth in colorectal cancer by neurotransmitter GABA signaling., PMID:37294054
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way., PMID:37149633
Identification of miRNA-mediated gene regulatory networks in L-methionine exposure counteracts cocaine-conditioned place preference in mice., PMID:36744178
May EPH/Ephrin Targeting Revolutionize Lung Cancer Treatment?, PMID:36613532
Eph and Ephrin Variants in Malaysian Neural Tube Defect Families., PMID:35741713
Methylation- and homologous recombination deficiency-related mutant genes predict the prognosis of lung adenocarcinoma., PMID:35238419
Artesunate-induced Cellular Effects Are Mediated by Specific EPH Receptors and Ephrin Ligands in Breast Carcinoma Cells., PMID:34949656
Free Fatty Acid Species Differentially Modulate the Inflammatory Gene Response in Primary Human Skeletal Myoblasts., PMID:34943232
Genomic Instability of Mutation-Derived Gene Prognostic Signatures for Hepatocellular Carcinoma., PMID:34676211
Investigation of Key Signaling Pathways Associating miR-204 and Common Retinopathies., PMID:34646884
Molecular insight into the affinity, specificity and cross-reactivity of systematic hepatocellular carcinoma RALT interaction profile with human receptor tyrosine kinases., PMID:34618235
The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs., PMID:34431498
The EphB6 Receptor: Kinase-Dead but Very Much Alive., PMID:34360976
Tumor immune microenvironment of primary colorectal adenocarcinomas metastasizing to the liver or lungs., PMID:34351649
Determining the effects of Ephrin Type B Receptor 6 and Type A Receptor 3 on facilitating colorectal epithelial cell malignant transformation., PMID:34196214
TTK Isoforms Interact with Two Regions of the Mep-1 Protein of Drosophila melanogaster., PMID:34189645
Prognostic value of members of NFAT family for pan-cancer and a prediction model based on NFAT2 in bladder cancer., PMID:33962392
Structure of the EphB6 receptor ectodomain., PMID:33770085
Ginsenoside ameliorated ventilator-induced lung injury in rats., PMID:33292607
Effects of adolescent intermittent ethanol on hippocampal expression of glutamate homeostasis and astrocyte-neuronal tethering proteins in male and female rats., PMID:33217775
Status of kinases in Epstein-Barr virus and Helicobacter pylori Coinfection in gastric Cancer cells., PMID:32993565
The gut microbiota regulates autism-like behavior by mediating vitamin B6 homeostasis in EphB6-deficient mice., PMID:32819434
The PI3Kα inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation., PMID:32814167
DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression., PMID:32754286
Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases., PMID:32619402
Kinome multigenic panel identified novel druggable EPHB4-V871I somatic variant in high-risk neuroblastoma., PMID:32336043
The receptor tyrosine kinase EPHB6 regulates catecholamine exocytosis in adrenal gland chromaffin cells., PMID:32321761
Cataloguing the dead: breathing new life into pseudokinase research., PMID:32053275
Eph receptor signalling: from catalytic to non-catalytic functions., PMID:31406248
Metabolic Engineering of the MEP Pathway in Bacillus subtilis for Increased Biosynthesis of Menaquinone-7., PMID:31250633
LncRNA DGCR5 regulates the non-small cell lung cancer cell growth, migration, and invasion through regulating miR-211-5p/EPHB6 axis., PMID:31241800
Ephrin/Eph receptor interaction facilitates macrophage recognition of differentiating human erythroblasts., PMID:31197068
EPHB6 mutation induces cell adhesion-mediated paclitaxel resistance via EPHA2 and CDH11 expression., PMID:31160603
EPHB6 controls catecholamine biosynthesis by up-regulating tyrosine hydroxylase transcription in adrenal gland chromaffin cells., PMID:30824540
Glypican-3 and Hep Par-1 are Useful Biomarkers in the Cytologic Assessment of Ascites., PMID:30383541
Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism., PMID:30262919