Catalog No.
YHA33101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser467
Predicted molecular weight
55.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14879
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interferon-induced protein with tetratricopeptide repeats 3, IFIT-3, CIG49, ISG-60, Interferon-induced 60 kDa protein, IFI-60K, Interferon-induced protein with tetratricopeptide repeats 4, IFIT-4, Retinoic acid-induced gene G protein, P60, RIG-G, IFIT3, CIG-49, IFI60, IFIT4, ISG60
Silencing IFIT3 suppresses the EGFR/VEGF pathway and modulates SOCS1 to attenuate skin fibrosis in systemic sclerosis., PMID:40515878
The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein., PMID:40512405
IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency., PMID:40497724
New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics., PMID:40421421
Virus-specific host responses and gene signatures following infection with major SARS-CoV-2 variants of concern: role of ZBP1 in viral clearance and lung inflammation., PMID:40416961
IFIT3 inhibits transmissible gastroenteritis virus (TGEV) infection by promoting the phosphorylation of TBK1 and STAT1, which enhances the innate immune response., PMID:40381424
Comprehensive bioinformatics analysis uncover molecular pathways shared between osteoarthritis and atherosclerosis., PMID:40335993
BCOR and ZC3H12A suppress a core stemness program in exhausted CD8+ T cells., PMID:40327039
Verification of biological markers of subacute cutaneous lupus erythematosus via TMT labelling proteomics combined with transcriptome data., PMID:40323689
Insight into mechanism of ALKBH5-mediated N6-methyladenosine (m6A) regulating porcine epidemic diarrhea virus infection in IPEC-J2 cells., PMID:40280045
Identification of key candidates associated with chronic hepatitis E viral infection., PMID:40255307
Cilia Plays a Pivotal Role in the Hypersecretion of Airway Mucus in Mice., PMID:40231527
Immunomodulatory roles of autophagic flux and IFIT in human ectocervical cells upon Trichomonas vaginalis infection., PMID:40220619
Acevaltrate overcomes myeloma resistance to bortezomib via pyroptosis by promoting BAX translocalization to mitochondria., PMID:40180268
Peptidomic profiling of mesenchymal stem cell-derived extracellular vesicles and anti-inflammatory activity of degraded peptides., PMID:40096816
Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2., PMID:40066622
IFIT3: a crucial mediator in innate immunity and tumor progression with therapeutic implications., PMID:40061935
IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency., PMID:40027740
Short 5' UTRs serve as a marker for viral mRNA translation inhibition by the IFIT2-IFIT3 antiviral complex., PMID:39990370
HOXD10: A novel gene implicated in human Müllerian duct anomalies., PMID:39987682
Robust antiviral innate immune response and miRNA regulatory network were identified in ZIKV-infected cells: implications in the pathogenesis of ZIKV infection., PMID:39955676
FAM210B activates STAT1/IRF9/IFIT3 axis by upregulating IFN-α/β expression to impede the progression of lung adenocarcinoma., PMID:39900908
PFKFB3 decreases α-ketoglutarate production while partial PFKFB3 knockdown in macrophages ameliorates arthritis in tumor necrosis factor-transgenic mice., PMID:39870011
Exploring gene expression, alternative splicing events and RNA-binding proteins changes in PBMC from patients with hyperuricemia., PMID:39828062
Unravelling the transcriptomic symphony of muscle ageing: key pathways and hub genes altered by ageing and caloric restriction in rat muscle revealed by RNA sequencing., PMID:39800693
α7-Nicotinic Acetylcholine Receptor Activation Modulates BV2 Microglial Plasticity via miR-21/TNF-α/NFκB in Oxygen-Glucose Deprivation/Reoxygenation., PMID:39718716
The expression and prognostic value of IFIT3 in esophageal squamous cell carcinoma., PMID:39697707
Potential protective role of interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) in COVID-19., PMID:39664492
Causal effect of psoriasis on aortic valve stenosis: a two-sample Mendelian randomization study., PMID:39483265
Identification of Aberrant Expression of Gemcitabine-Targeting Proteins in Drug-Resistant Cells Using an Activity-Based Gemcitabine Probe., PMID:39465385
Peripheral mononuclear cells and systemic lupus erythematosus association: Integrated study of single-cell sequencing and mendelian randomization analysis., PMID:39404110
Proteomic analysis of HeLa cells after stable transfection with the Chlamydia trachomatis CT143 gene., PMID:39374816
IFIT3 mediates TBK1 phosphorylation to promote activation of pDCs and exacerbate systemic sclerosis in mice., PMID:39305055
Adopting Integrated Bioinformatics and Systems Biology Approaches to Pinpoint the COVID-19 Patients' Risk Factors That Uplift the Onset of Posttraumatic Stress Disorder., PMID:39281421
Double-negative T cells with a distinct transcriptomic profile are abundant in the peripheral blood of patients with breast cancer., PMID:39254769
Immunological landscape of human lymphoid explants during measles virus infection., PMID:39253971
Unraveling the roles of IFIT3 gene and immune-metabolic pathways in psoriasis: a bioinformatics exploration for diagnostic markers and therapeutic targets., PMID:39239353
Unveiling Potential Biomarkers for Urinary Tract Infection: An Integrated Bioinformatics Approach., PMID:39224398
Genome-wide characterization of extrachromosomal circular DNA in SLE and functional analysis reveal their association with apoptosis., PMID:39173965
Immune horses rapidly increase antileukoproteinase and lack type I interferon secretion during mucosal innate immune responses against equine herpesvirus type 1., PMID:39162558
Circ_BBS9 as an early diagnostic biomarker for lung adenocarcinoma: direct interaction with IFIT3 in the modulation of tumor immune microenvironment., PMID:39139574
Analysis of Key Genes Related to Systemic Lupus Erythematosus and COVID-19., PMID:39129283
RNAseq of Gingival Fibroblasts Exposed to PRF Membrane Lysates and PRF Serum., PMID:39120336
Kaempferol Alleviates Injury in Human Retinal Pigment Epithelial Cells via STAT1 Ubiquitination-Mediated Degradation of IRF7., PMID:39082331
Cap-related modifications of RNA regulate binding to IFIT proteins., PMID:39009378
Expression of ISG60 is induced by TLR3 signaling in BEAS‑2B bronchial epithelial cells: Possible involvement in CXCL10 expression., PMID:38963029
A comparative analysis of RNA-Seq and NanoString technologies in deciphering viral infection response in upper airway lung organoids., PMID:38957806
Interferon-stimulated gene 56 positively regulates Toll-like receptor 3-mediated CXCL10 expression in human renal proximal tubular epithelial cells., PMID:38923445
diABZI and poly(I:C) inhibit osteoclastic bone resorption by inducing IRF7 and IFIT3., PMID:38874138
Identification of modules and key genes associated with breast cancer subtypes through network analysis., PMID:38811600
For research use only. Not for human or drug use.
