Catalog No.
YHA28001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys288
Predicted molecular weight
33.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14732
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Inositol monophosphatase 2, IMP 2, IMPase 2, 3.1.3.25, Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2, IMPA2, IMP.18P
The importin α proteins IMPA1, IMPA2, and IMPA4 play redundant roles in suppressing autoimmunity in Arabidopsis thaliana., PMID:39658755
IMPA2 blocks cervical cancer cell apoptosis and induces paclitaxel resistance through p53-mediated AIFM2 regulation., PMID:37140233
LINC01311 exerts an inhibitory effect in thyroid cancer progression by targeting the miR-146b-5p/IMPA2 axis., PMID:36423383
COVID-19 Salivary Protein Profile: Unravelling Molecular Aspects of SARS-CoV-2 Infection., PMID:36233441
Identification of candidate genes associated with bacterial and viral infections in wild boars hunted in Tuscany (Italy)., PMID:35581286
An Arabidopsis nonhost resistance gene, IMPORTIN ALPHA 2 provides immunity against rice sheath blight pathogen, Rhizoctonia solani., PMID:35243446
Novel imidazo[1,2-a]pyridine derivatives induce apoptosis and cell cycle arrest in non-small cell lung cancer by activating NADPH oxidase mediated oxidative stress., PMID:35065161
Identification of key tumor stroma-associated transcriptional signatures correlated with survival prognosis and tumor progression in breast cancer., PMID:35020130
SWO1 modulates cell wall integrity under salt stress by interacting with importin ɑ in Arabidopsis., PMID:37676567
Development and validation of a metabolic gene signature for predicting overall survival in patients with colon cancer., PMID:32772211
A novel function of IMPA2, plays a tumor-promoting role in cervical cancer., PMID:32409648
Comparative toxicoproteogenomics of mouse and rat liver identifies TCDD-resistance genes., PMID:31511937
Dysregulation of the miR-25-IMPA2 axis promotes metastatic progression in clear cell renal cell carcinoma., PMID:31202813
Exploring Genetic Variability at PI, GSK3, HPA, and Glutamatergic Pathways in Lithium Response: Association With IMPA2, INPP1, and GSK3B Genes., PMID:26267417
Hippocampal transcriptional and neurogenic changes evoked by combination yohimbine and imipramine treatment., PMID:25784603
Seawater acclimation and inositol monophosphatase isoform expression in the European eel (Anguilla anguilla) and Nile tilapia (Orechromis niloticus)., PMID:23739342
Genetic variability at IMPA2, INPP1 and GSK3β increases the risk of suicidal behavior in bipolar patients., PMID:23453640
Human myo-inositol monophosphatase 2 rescues the nematode thermotaxis mutant ttx-7 more efficiently than IMPA1: functional and evolutionary considerations of the two mammalian myo-inositol monophosphatase genes., PMID:23205734
In silico study on the substrate binding manner in human myo-inositol monophosphatase 2., PMID:21213002
Behavioral analyses of transgenic mice harboring bipolar disorder candidate genes, IMPA1 and IMPA2., PMID:20153384
Suggestive evidence for a new locus for epilepsy with heterogeneous phenotypes on chromosome 17q., PMID:19914042
KCNK17 genetic variants in ischemic stroke., PMID:19647252
Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia., PMID:19066393
Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures., PMID:17340635
eIF2B and oligodendrocyte survival: where nature and nurture meet in bipolar disorder and schizophrenia?, PMID:17329232
Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: implications for oligodendrocyte viability., PMID:17239488
Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1., PMID:17068342
Lack of lithium-like behavioral and molecular effects in IMPA2 knockout mice., PMID:16841073
C18orf1 located on chromosome 18p11.2 may confer susceptibility to schizophrenia., PMID:15074360
Characterization of two genes, Impa1 and Impa2 encoding mouse myo-inositol monophosphatases., PMID:11418250
For research use only. Not for human or drug use.
