Catalog No.
YHA26901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr293-Ser589
Predicted molecular weight
34.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14682
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ectoderm-neural cortex protein 1, ENC-1, Kelch-like protein 37, Nuclear matrix protein NRP/B, p53-induced gene 10 protein, ENC1, KLHL37, NRPB, PIG10
Statement of Retraction: The LOXL1 antisense RNA 1 (LOXL1-AS1)/microRNA-423-5p (miR-423-5p)/ectodermal-neural cortex 1 (ENC1) axis promotes cervical cancer through the mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway., PMID:40263947
ENC1 Promotes the Malignant Progression and Metastasis by Suppressing TRIM21 Mediated Vimentin Degradation in Wilms Tumor., PMID:40222040
Comprehensive pan-cancer analysis reveals ENC1 as a promising prognostic biomarker for tumor microenvironment and therapeutic responses., PMID:39455818
RNA-binding proteins potentially regulate alternative splicing of immune/inflammatory-associated genes during the progression of generalized pustular psoriasis., PMID:39158708
CircXRN2 accelerates colorectal cancer progression through regulating miR-149-5p/MACC1 axis and EMT., PMID:38291092
The emerging role of ectodermal neural cortex 1 in cancer., PMID:38177640
Expression and clinical significance of ENC1 in gastrointestinal tumors: Bioinformatics analysis based on a public gene database., PMID:37201052
Evaluation of potential anti-metastatic and antioxidative abilities of natural peptides derived from Tecoma stans (L.) Juss. ex Kunth in A549 cells., PMID:35818360
The LOXL1 antisense RNA 1 (LOXL1-AS1)/microRNA-423-5p (miR-423-5p)/ectodermal-neural cortex 1 (ENC1) axis promotes cervical cancer through the mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway., PMID:35015607
Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection., PMID:34675930
Revelation of Pivotal Genes Pertinent to Alzheimer's Pathogenesis: A Methodical Evaluation of 32 GEO Datasets., PMID:34668150
A 3-Gene-Based Diagnostic Signature in Alzheimer's Disease., PMID:34521086
Aberrant super-enhancer-driven oncogene ENC1 promotes the radio-resistance of breast carcinoma., PMID:34362881
ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness., PMID:33816464
Ectodermal‑neural cortex 1 affects the biological function of lung cancer through the MAPK pathway., PMID:33693958
Epigenetics of Muscle- and Brain-Specific Expression of KLHL Family Genes., PMID:33182325
Ectodermal-neural cortex 1 as a novel biomarker predicts poor prognosis and induces metastasis in breast cancer by promoting Wnt/β-catenin pathway., PMID:32618411
Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function., PMID:32045384
Identification of Transcriptional Signatures of Colon Tumor Stroma by a Meta-Analysis., PMID:31186640
Serum Proteomic Signatures of Male Breast Cancer., PMID:30850364
Long noncoding RNA ANRIL regulates endothelial cell activities associated with coronary artery disease by up-regulating CLIP1, EZR, and LYVE1 genes., PMID:30655286
Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity., PMID:30309776
Low expression of ENC1 predicts a favorable prognosis in patients with ovarian cancer., PMID:30125994
Sclerostin Antibody Reverses the Severe Sublesional Bone Loss in Rats After Chronic Spinal Cord Injury., PMID:29931461
Expression analyzes of early factors in midbrain differentiation programs., PMID:28958789
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data., PMID:28441426
Ectodermal-Neural Cortex 1 Isoforms Have Contrasting Effects on MC3T3-E1 Osteoblast Mineralization and Gene Expression., PMID:27996212
Inferring Evolution of Habitat Usage and Body Size in Endangered, Seasonal Cynopoeciline Killifishes from the South American Atlantic Forest through an Integrative Approach (Cyprinodontiformes: Rivulidae)., PMID:27428070
Inhibition of Ectodermal-Neural Cortex 1 Protects Neural Cells from Apoptosis Induced by Hypoxia and Hypoglycemia., PMID:27039095
Transcriptome profiling of human FoxP3+ regulatory T cells., PMID:26686412
A Whole Methylome CpG-SNP Association Study of Psychosis in Blood and Brain Tissue., PMID:26656881
ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress., PMID:26637326
Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis., PMID:25970467
Identification of a subtype-specific ENC1 gene related to invasiveness in human pituitary null cell adenoma and oncocytomas., PMID:24916845
Anabolic steroids reduce spinal cord injury-related bone loss in rats associated with increased Wnt signaling., PMID:24090150
Saltatory evolution of the ectodermal neural cortex gene family at the vertebrate origin., PMID:23843192
ENC1-like integrates the retinoic acid/FGF signaling pathways to modulate ciliogenesis of Kupffer's Vesicle during zebrafish embryonic development., PMID:23201577
Gene trees, species trees, and morphology converge on a similar phylogeny of living gars (Actinopterygii: Holostei: Lepisosteidae), an ancient clade of ray-finned fishes., PMID:22445447
Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses., PMID:22232672
Reconciling gene trees of eastern North American minnows., PMID:21669293
Characterization of differential gene expression in adrenocortical tumors harboring beta-catenin (CTNNB1) mutations., PMID:21565795
Enc1 expression in the chick telencephalon at intermediate and late stages of development., PMID:19824088
Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level., PMID:19424503
Expression of ectodermal neural cortex 1 and its association with actin during the ovulatory process in the rat., PMID:19372205
Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma., PMID:18803327
The inhibition of Wnt/beta-catenin signalling by 1alpha,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells., PMID:17395983
Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening., PMID:16516881
Transgenic ice nucleation-active Enterobacter cloacae reduces cold hardiness of corn borer and cotton bollworm larvae., PMID:16329857
Pallial expression of Enc1 RNA in postnatal mouse telencephalon., PMID:16144629
Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway., PMID:15983046
For research use only. Not for human or drug use.
