Catalog No.
YHA08701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly89-Ala240
Predicted molecular weight
19.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00303
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Eukaryotic translation initiation factor 3 subunit F, eIF3f, Deubiquitinating enzyme eIF3f, 3.4.19.12, Eukaryotic translation initiation factor 3 subunit 5, eIF-3-epsilon, eIF3 p47, EIF3F, EIF3S5
The RNA-stability-independent role of the RNA m6A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance., PMID:40480228
Multiomics profiles of genome-wide alterations in H3K27ac in different lung lobes after acute graft-versus-host disease with MSCs treatment., PMID:40443676
Multi-omics analysis revealed significant metabolic changes in brain cancer cells treated with paclitaxel and/or topotecan., PMID:39524752
eIF3f Mediates SGOC Pathway Reprogramming by Enhancing Deubiquitinating Activity in Colorectal Cancer., PMID:37544925
Dissecting the roles of EIF4G homologs reveals DAP5 as a modifier of CGG repeat-associated toxicity in a Drosophila model of FXTAS., PMID:37352983
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility., PMID:37335463
Gaining insight into the role of FoxO1 in the progression of disuse-induced skeletal muscle atrophy., PMID:35947892
Forming cytoplasmic stress granules PURα suppresses mRNA translation initiation of IGFBP3 to promote esophageal squamous cell carcinoma progression., PMID:35945453
Identification of recurrent pathogenic alleles using exome sequencing data: Proof-of-concept study of Russian subjects., PMID:35026467
Comparative transcriptomic analysis reveals the gonadal development-related gene response to environmental temperature in Mauremys mutica., PMID:34689019
Protein co-expression network-based profiles revealed from laser-microdissected cancerous cells of lung squamous-cell carcinomas., PMID:34642392
USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing., PMID:34614178
Molecular Regulation of Skeletal Muscle Growth and Organelle Biosynthesis: Practical Recommendations for Exercise Training., PMID:33800501
EIF3F-related neurodevelopmental disorder: refining the phenotypic and expanding the molecular spectrum., PMID:33736665
Berberine induces anti-atopic dermatitis effects through the downregulation of cutaneous EIF3F and MALT1 in NC/Nga mice with atopy-like dermatitis., PMID:33539814
A subset of microRNAs in the Dlk1-Dio3 cluster regulates age-associated muscle atrophy by targeting Atrogin-1., PMID:32495509
A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosis., PMID:32030451
Obesity significantly alters the human sperm proteome, with potential implications for fertility., PMID:32026202
Identification of hub-methylated differentially expressed genes in patients with gestational diabetes mellitus by multi-omic WGCNA basing epigenome-wide and transcriptome-wide profiling., PMID:31886571
A Translation-Activating Function of MIWI/piRNA during Mouse Spermiogenesis., PMID:31835033
Quantitative proteomic analysis reveals high interference on protein expression of H9c2 cells activated with glucose and cardiotonic steroids., PMID:31629057
Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F., PMID:31527668
Knockdown of RPL34 suppresses osteosarcoma cell proliferation likely through EIF3/FAU signaling pathway., PMID:35116824
eIF3f depletion impedes mouse embryonic development, reduces adult skeletal muscle mass and amplifies muscle loss during disuse., PMID:31026345
Metabolic derangements of skeletal muscle from a murine model of glioma cachexia., PMID:30635036
Estrogen receptor α promotes protein synthesis by fine-tuning the expression of the eukaryotic translation initiation factor 3 subunit f (eIF3f)., PMID:30573685
Quantifying the contribution of recessive coding variation to developmental disorders., PMID:30409806
SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F., PMID:30206144
Meta-analysis of gene expression profiles of peripheral blood cells in systemic lupus erythematosus., PMID:30084812
Decreased abundance of eIF4F subunits predisposes low birth weight neonatal pigs to reduced muscle hypertrophy., PMID:30070606
δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patients., PMID:30031388
Identification of differentially expressed genes and pathways in mice exposed to mixed field neutron/photon radiation., PMID:29954325
The function and clinical significance of eIF3 in cancer., PMID:29908282
The Possible Role of Eukaryotic Translation Initiation Factor 3 Subunit e (eIF3e) in the Epithelial-Mesenchymal Transition in Adenomyosis., PMID:29871559
Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest., PMID:29030970
Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle., PMID:28694500
The eIF3 complex of Trypanosoma brucei: composition conservation does not imply the conservation of structural assembly and subunits function., PMID:27932584
The Rice Eukaryotic Translation Initiation Factor 3 Subunit f (OseIF3f) Is Involved in Microgametogenesis., PMID:27200010
eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells., PMID:26988917
The eukaryotic translation initiation factor 3f (eIF3f) interacts physically with the alpha 1B-adrenergic receptor and stimulates adrenoceptor activity., PMID:26497985
MD11-mediated delivery of recombinant eIF3f induces melanoma and colorectal carcinoma cell death., PMID:26052528
Clinicopathologic Implications of Eukaryotic Initiation Factor 3f and Her-2/neu Expression in Gastric Cancer., PMID:25684180
The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis., PMID:25539953
Regulation of ubiquitin proteasome pathway molecular markers in response to endurance and resistance exercise and training., PMID:25104573
Expression of eukaryotic initiation factor 3f is associated with prognosis in gastric carcinomas., PMID:24732644
Decreased expression of eukaryotic initiation factor 3f is an adverse prognostic factor for stage I-III gastric cancer., PMID:24678890
Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise., PMID:24550841
Influence of divergent exercise contraction mode and whey protein supplementation on atrogin-1, MuRF1, and FOXO1/3A in human skeletal muscle., PMID:24458747
Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase., PMID:24396066
Chronic alcohol consumption disrupts myocardial protein balance and function in aged, but not adult, female F344 rats., PMID:24226028