Catalog No.
YHA03101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly52-Pro380
Predicted molecular weight
38.69 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00154
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cytosolic acyl coenzyme A thioester hydrolase, 3.1.2.2, Acyl-CoA thioesterase 7, Brain acyl-CoA hydrolase, BACH, hBACH, CTE-IIa, CTE-II, Long chain acyl-CoA thioester hydrolase, ACOT7, BACH
Proteomic signatures of retinal pigment epithelium-derived exosomes in myopic and non-myopic tree shrew eyes., PMID:40330779
Discovery of myeloid zinc finger (MZF) 1 nuclear bodies., PMID:39954358
Construction and Validation of a Novel Butyrylation-Related Gene Signature Related to Prognosis, Clinical Implications, and Immune Microenvironment Characterization of Hepatocellular Carcinoma., PMID:39926543
Role of Acyl-CoA Thioesterase 7 in Regulating Fatty Acid Metabolism and Its Contribution to the Onset and Progression of Bovine Clinical Mastitis., PMID:39684757
Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways., PMID:39494346
m6A-driven NAT10 translation facilitates fatty acid metabolic rewiring to suppress ferroptosis and promote ovarian tumorigenesis through enhancing ACOT7 mRNA acetylation., PMID:39390256
ACOT7 positively regulated by CREB1 promotes the progression of cutaneous melanoma., PMID:39142244
Elucidating the role of S100A10 in CD8+ T cell exhaustion and HCC immune escape via the cPLA2 and 5-LOX axis., PMID:39117605
ACOT7, a candidate and novel serum biomarker of Alzheimer's disease., PMID:39026992
eEF1A1 regulates the expression and alternative splicing of genes associated with Parkinson's disease in U251 cells., PMID:38776049
USP3 promotes cisplatin resistance in non-small cell lung cancer cells by suppressing ACOT7-regulated ferroptosis., PMID:38502867
TMT-labeled quantitative malonylome analysis on the longissimus dorsi muscle of Laiwu pigs reveals the role of ACOT7 in fat deposition., PMID:38395145
CDK5R1, GSE1, HSPG2 and WDFY3 as indirect epigenetic-sensitive genes in atrial fibrillation., PMID:37991085
Amyloid fibril formation, structure and domain swapping of acyl-coenzyme A thioesterase-7., PMID:37042241
ARNTL2 upregulation of ACOT7 promotes NSCLC cell proliferation through inhibition of apoptosis and ferroptosis., PMID:37003979
One novel ACOT7-NPHP4 fusion gene identified in one patient with acute lymphoblastic leukemia: a case report., PMID:36316773
ACOT7 protects epidermal stem cells against lipid peroxidation., PMID:36036847
A Nucleophilic Chemical Probe Targeting Electrophilic Functional Groups in an Untargeted Way to Explore Cysteine Modulators in Natural Products., PMID:35766822
A set of gene knockouts as a resource for global lipidomic changes., PMID:35732804
Acyl-Coa Thioesterases: A Rheostat That Controls Activated Fatty Acids Modulates Dengue Virus Serotype 2 Replication., PMID:35215835
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma., PMID:34993160
Identification of Mitochondrial-Related Prognostic Biomarkers Associated With Primary Bile Acid Biosynthesis and Tumor Microenvironment of Hepatocellular Carcinoma., PMID:33868990
LPCAT2 Methylation, a Novel Biomarker for the Severity of Cedar Pollen Allergic Rhinitis in Japan., PMID:33356413
Shared DNA methylation signatures in childhood allergy: The MeDALL study., PMID:33338541
Metabolic and functional specialisations of the pancreatic beta cell: gene disallowance, mitochondrial metabolism and intercellular connectivity., PMID:32894309
Analysis of plasma metabolic profile, characteristics and enzymes in the progression from chronic hepatitis B to hepatocellular carcinoma., PMID:32701483
Interaction between ACOT7 and LncRNA NMRAL2P via Methylation Regulates Gastric Cancer Progression., PMID:32469171
Multiple mitochondrial thioesterases have distinct tissue and substrate specificity and CoA regulation, suggesting unique functional roles., PMID:31676684
GRP94 Is Involved in the Lipid Phenotype of Brain Metastatic Cells., PMID:31395819
Loss of ACOT7 potentiates seizures and metabolic dysfunction., PMID:31039008
DNA methylation and allergic sensitizations: A genome-scale longitudinal study during adolescence., PMID:30762239
Regulatory mechanism of fatty acid‑CoA metabolic enzymes under endoplasmic reticulum stress in lung cancer., PMID:30132556
Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach., PMID:29692868
Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)., PMID:29552625
Transcriptome analysis reveals the molecular mechanism of hepatic fat metabolism disorder caused by Muscovy duck reovirus infection., PMID:28911249
Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ-p53-p21 signaling pathway., PMID:28518146
WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms., PMID:28472401
Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages., PMID:28416579
Epigenome-wide DNA methylation study of IgE concentration in relation to self-reported allergies., PMID:28322575
An epigenome-wide association study of total serum IgE in Hispanic children., PMID:28069425
Astrocyte arachidonate and palmitate uptake and metabolism is differentially modulated by dibutyryl-cAMP treatment., PMID:27255639
Disallowance of Acot7 in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion., PMID:26861785
Metabolic and tissue-specific regulation of acyl-CoA metabolism., PMID:25760036
Identification of acyl-CoA thioesterase in mouse mesenteric lymph nodes., PMID:23649344
Acyl coenzyme A thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity., PMID:23459938
Upregulation of fatty acyl-CoA thioesterases in the heart and skeletal muscle of rats fed a high-fat diet., PMID:21212523
Functional and structural properties of mammalian acyl-coenzyme A thioesterases., PMID:20470824
[CENTB5 gene expression in human and mouse]., PMID:19548526
Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation., PMID:17563367
Alternative exon usage selectively determines both tissue distribution and subcellular localization of the acyl-CoA thioesterase 7 gene products., PMID:17514357
For research use only. Not for human or drug use.
