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Recombinant Human PFKM Protein, N-His

Catalog #:   YHC31701 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P08237
Protein length: Met1-Val780
Overview

Catalog No.

YHC31701

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Met1-Val780

Predicted molecular weight

87.34 kDa

Nature

Recombinant

Concentration

0.22 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P08237

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.02% NLS.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

ATP-dependent 6-phosphofructokinase, muscle type, PFK-M, Phosphofructo-1-kinase isozyme A, 6-phosphofructokinase type A, PFK-A, PFKM, PFKX, ATP-PFK, Phosphohexokinase

Data Image
  • SDS-PAGE
    SDS-PAGE for Recombinant Human PFKM Protein
References

TXNIP participates in the pathogenesis of PCOS by regulating glycolysis in granulosa cells., PMID:40499496

Expanding the clinical phenotype and understanding the biochemical consequences of Muscle Glycogen Synthase Deficiency (GSD0B)., PMID:40398079

PFKM-Mediated Glycolysis: A Pathway for ASIC1 to Enhance Cell Survival in the Acidic Microenvironment of Liver Cancer., PMID:40149892

Gua Sha Alleviates Radiculitis-Induced Pain Via HIF-1α-Mediated Metabolic Reprogramming Pathway in Rats., PMID:40130025

Glucagon-like peptide-1 receptor signaling activation in alveolar type II cells enhances lung development in neonatal rats exposed to hyperoxia., PMID:40080965

Identification and validation of transcriptome-wide association study-derived genes as potential druggable targets for osteoarthritis., PMID:40079200

Knockdown of SESN2 Exacerbates Cerebral Ischemia-Reperfusion Injury Through Enhancing Glycolysis via the mTOR/HIF-1α Pathway., PMID:40032632

Chloroquine Suppresses Colorectal Cancer Progression via Targeting CHKA and PFKM to inhibit the PI3K/AKT Pathway and the Warburg Effect., PMID:39990656

Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia., PMID:39725939

Exploring variances in meat quality between Qingyuan partridge chicken and Cobb broiler: Insights from combined multi-omics analysis., PMID:39721276

Gene ontology defines pre-post- hatch energy dynamics in the complexus muscle of broiler chickens., PMID:39633257

TPM4 condensates glycolytic enzymes and facilitates actin reorganization under hyperosmotic stress., PMID:39622827

rTM reprograms macrophages via the HIF-1α/METTL3/PFKM axis to protect mice against sepsis., PMID:39549085

The Role of PI3K/AKT/HIF-1α Pathway in the Effect of Nano-TiO2 on Lactate Production in TM4 Cells., PMID:39533807

Genetics of Exertional Heat Illness: Revealing New Associations and Expanding Heterogeneity., PMID:39457051

Phosphofructokinase-1 in Cancer: A Promising Target for Diagnosis and Therapy., PMID:39171598

Distinct maturation, glucose metabolism, and inflammatory function of human monocytes-derived IDECs mediated by anti-IgE and Pam3CSK4 alone or in combination., PMID:39086490

Nano-Se exhibits limited protective effect against heat stress induced poor breast muscle meat quality of broilers compared with other selenium sources., PMID:38972969

A Ratiometric Catalog of Protein Isoform Shifts in the Cardiac Fetal Gene Program., PMID:38645170

The characterization of protein lactylation in relation to cardiac metabolic reprogramming in neonatal mouse hearts., PMID:38479452

[Effect and mechanism of Yueju Pills on breast cancer induced by DMBA in rats]., PMID:38403319

RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling., PMID:38368381

Glutaminase potentiates the glycolysis in esophageal squamous cell carcinoma by interacting with PDK1., PMID:38353358

Blockade of C5aR1 resets M1 via gut microbiota-mediated PFKM stabilization in a TLR5-dependent manner., PMID:38331868

NAT10 mediated ac4C acetylation driven m6A modification via involvement of YTHDC1-LDHA/PFKM regulates glycolysis and promotes osteosarcoma., PMID:38233839

Harpagide inhibits the TNF-α-induced inflammatory response in rat articular chondrocytes by the glycolytic pathways for alleviating osteoarthritis., PMID:38142643

Synergistic suppressive effects on triple-negative breast cancer by the combination of JTC-801 and sodium oxamate., PMID:37970352

Phosphofructokinase family genes in grass carp: Molecular identification and tissue-specific expression in response to glucose, insulin and glucagon., PMID:37673204

Transcriptome profiling of A549 non-small cell lung cancer cells in response to Trichinella spiralis muscle larvae excretory/secretory products., PMID:37601754

Analysis of the role of glucose metabolism-related genes in dilated cardiomyopathy based on bioinformatics., PMID:37559624

Scraping Therapy Improved Muscle Regeneration through Regulating GLUT4/Glycolytic and AMPK/mTOR/4EBP1 Pathways in Rats with Lumbar Multifidus Injury., PMID:37397163

Cardiac Molecular Remodeling by Anticancer Drugs: Doxorubicin Affects More Metabolism While Mitoxantrone Impacts More Autophagy in Adult CD-1 Male Mice., PMID:37371499

RELA governs a network of islet-specific metabolic genes necessary for beta cell function., PMID:37311878

Aspirin induces immunogenic cell death and enhances cancer immunotherapy in colorectal cancer., PMID:37290325

Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis of the Blood Proteome., PMID:37212950

Bioinformatics identification of prognostic genes and potential interaction analysis in renal cell carcinoma., PMID:37180655

Senecavirus A-induced glycolysis facilitates virus replication by promoting lactate production that attenuates the interaction between MAVS and RIG-I., PMID:37126525

Comparative Proteomic Analysis of Glycolytic and Oxidative Muscle in Pigs., PMID:36833290

Associative analysis of multi-omics data indicates that acetylation modification is widely involved in cigarette smoke-induced chronic obstructive pulmonary disease., PMID:36714109

RNAi screening reveals a synthetic chemical-genetic interaction between ATP synthase and PFK1 in cancer cells., PMID:36601784

Mining of chicken muscle growth genes and the function of important candidate gene RPL3L in muscle development., PMID:36407004

A proteomic approach to identify biomarkers of foal meat quality: A focus on tenderness, color and intramuscular fat traits., PMID:36345099

Exploring metabolism in scleroderma reveals opportunities for pharmacological intervention for therapy in fibrosis., PMID:36304460

Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM., PMID:36253358

Differential expression of aerobic oxidative metabolism-related proteins in diabetic urinary exosomes., PMID:36187097

Black Ginger (Kaempferia parviflora) Extract Enhances Endurance Capacity by Improving Energy Metabolism and Substrate Utilization in Mice., PMID:36145222

Skeletal-Muscle-Specific Overexpression of Chrono Leads to Disruption of Glucose Metabolism and Exercise Capacity., PMID:36013411

Association of PFKM gene polymorphisms and susceptibility to cryptorchidism in a Chinese Han population., PMID:35838787

PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis., PMID:35804014

Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy., PMID:35608632

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human PFKM Protein, N-His [YHC31701]
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