Catalog No.
YMC26401
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ser34-Asn246
Predicted molecular weight
25.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Z1R9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protease, serine 1 (trypsin 1), Trypsinogen 16, Prss1, Trygn16, trypsinogen
Gasdermin D-Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis., PMID:40439590
Emerging roles of ADAM6 and PRSS1 as novel diagnostic/prognostic biomarkers for acute lymphoblastic and myeloid leukemia in adults., PMID:40382561
The aggregation tendencies of the signal peptide regions of prone and not prone to aggregate proteins., PMID:40212812
Acinar cells modulate the tumor microenvironment through the promotion of M1 macrophage polarization via macrophage endocytosis in pancreatic cancer., PMID:40198509
Study of a panel of genetic mutations in fibrocalcific pancreatic diabetes (FCPD): SPINK1 (N34S) mutation unlikely to be relevant., PMID:39738564
Misfolding PRSS1 variant p.Ala61Val in a case of suspected intrauterine pancreatitis., PMID:39734120
Biallelic Loss of 7q34 (TRB) and 9p21.3 (CDKN2A/2B) in Adult Ph-Negative Acute T-Lymphoblastic Leukemia., PMID:39408811
A De Novo CaSR Missense Variant in Combination with Two Inherited Missense Variants in CFTR and SPINK1 Detected in a Patient with Chronic Pancreatitis., PMID:38927485
Exploring Infantile Epileptic Spasm Syndrome: A Proteomic Analysis of Plasma Using the Data-Independent Acquisition Approach., PMID:38857073
Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine., PMID:38760394
Diagnostic yield of repeat genetic testing in idiopathic chronic pancreatitis., PMID:38657903
The biomechanical proteins different between low myopic corneas and moderate to high myopic corneas in human., PMID:38472014
Genetic Factors Associated With Adverse Pregnancy Outcomes in Chronic Pancreatitis., PMID:38334943
Total Pancreatectomy with Islet Autotransplantation (TPIAT) as a Technique to Treat Chronic Idiopathic Pancreatitis: Early Experience Analysis., PMID:39896151
Genetic Investigations in Turkish Idiopathic Pancreatitis Patients Show Unique Characteristics., PMID:37823318
Association of Glycated Hemoglobin With a Risk of Pancreatic Cancer in High-Risk Individuals Based on Genetic and Family History., PMID:37800692
Clinical and Genetic Description of Hereditary Chronic Pancreatitis in Pakistani Children., PMID:37603299
Classification of PRSS1 variants responsible for chronic pancreatitis: An expert perspective from the Franco-Chinese GREPAN study group., PMID:37581535
Diagnosis of Immunoglobulin G4-related disease in a child with ligneous conjunctivitis: a novel mutation in plasminogen gene and plasminogen activator inhibitor-1 polymorphism., PMID:37577870
Spectrum of PRSS1, SPINK1, CTRC, CFTR, and CPA1 Gene Variants in Chronic Pancreatitis Patients in Russia., PMID:37389024
An artificial intelligence prediction model based on extracellular matrix proteins for the prognostic prediction and immunotherapeutic evaluation of ovarian serous adenocarcinoma., PMID:37388244
Research into the anti-pulmonary fibrosis mechanism of Renshen Pingfei formula based on network pharmacology, metabolomics, and verification of AMPK/PPAR-γ pathway of active ingredients., PMID:37308028
Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis., PMID:37155882
[Influence of environmental factors and polymorphic loci rs6580502 of the SPINK1 gene, rs10273639 of the PRSS1 gene, rs213950 of the CFTR gene on the risk of developing acute alcoholic-alimentary pancreatitis]., PMID:36883543
Mouse model of PRSS1 p.R122H-related hereditary pancreatitis highlights context-dependent effect of autolysis-site mutation., PMID:36797199
High-throughput proteomic characterization of seminal plasma from bulls with contrasting semen quality., PMID:36714547
A novel frameshift mutation in TRPV6 is associated with hereditary pancreatitis., PMID:36699452
The PRSS3P2 and TRY7 deletion copy number variant modifies risk for chronic pancreatitis., PMID:36517351
Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer., PMID:36484990
A rare PRSS1 p.S127C mutation is associated with chronic pancreatitis and causes misfolding-induced ER-stress., PMID:36369231
Acinar ATP8b1/LPC pathway promotes macrophage efferocytosis and clearance of inflammation during chronic pancreatitis development., PMID:36273194
Pleiotropic modifiers of age-related diabetes and neonatal intestinal obstruction in cystic fibrosis., PMID:36206743
Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression., PMID:36191639
WITHDRAWN: Clinical interpretation of PRSS1 gene variants in patients with pancreatitis., PMID:36057185
Expanding ACMG variant classification guidelines into a general framework., PMID:35974416
Mechanisms of pancreatic tumor suppression mediated by Xiang-lian pill: An integrated in silico exploration and experimental validation., PMID:35931303
The Clinical Utility of Soluble Serum Biomarkers in Autoimmune Pancreatitis: A Systematic Review., PMID:35884816
Identification of high-risk germline variants for the development of pancreatic cancer: Common characteristics and potential guidance to screening guidelines., PMID:35798629
Prediction of EVT6-NTRK3-Dependent Papillary Thyroid Cancer Using Minor Expression Profile., PMID:35737155
The clinical and genetic features of hereditary pancreatitis in South Australia., PMID:35578795
St13 protects against disordered acinar cell arachidonic acid pathway in chronic pancreatitis., PMID:35562743
Identification of potential pathogenic genes for severe aplastic anemia by whole-exome sequencing., PMID:35435273
Inherited pancreatic exocrine insufficiency and pancreatitis: When children transition to adult care., PMID:35331395
Improved NGS variant calling tool for the PRSS1-PRSS2 locus., PMID:35288441
Wild-Type Human PRSS2 and PRSS1R122H Cooperatively Initiate Spontaneous Hereditary Pancreatitis in Transgenic Mice., PMID:35288112
Haplotype-resolved de novo assembly of a Tujia genome suggests the necessity for high-quality population-specific genome references., PMID:35180379
Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis., PMID:35089416
Alcohol amplifies the association between common variants at PRSS1-PRSS2 locus and chronic pancreatitis in a dose-dependent manner., PMID:34996825
Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis., PMID:34797250
Common genetic signatures of Alzheimer's disease in Down Syndrome., PMID:33633844
For research use only. Not for human or drug use.
