Catalog No.
YXX18601
Expression system
E. coli
Species
Pseudomonas aeruginosa
Protein length
Met1-Gly115
Predicted molecular weight
13.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A0A0N9LSG8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fucophilic lectin LecB type-2, lecB
Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa-Burkholderia cenocepacia Infections: A Biophysical Study., PMID:40279549
Fluoro-Fucosylation Enables the Interrogation of the Lea-LecB Interaction by BioNMR Spectroscopy., PMID:39902623
High-Affinity Lectin Ligands Enable the Detection of Pathogenic Pseudomonas aeruginosa Biofilms: Implications for Diagnostics and Therapy., PMID:39735928
Bispecific Thio-Linked Disaccharides as Inhibitors of Pseudomonas Aeruginosa Lectins LecA (PA-IL) and LecB (PA-IIL): Dual-Targeting Strategy., PMID:39535852
The Pseudomonas aeruginosa lectin LecB modulates intracellular reactive oxygen species production in human neutrophils., PMID:37972111
Genomic variability correlates with biofilm phenotypes in multidrug resistant clinical isolates of Pseudomonas aeruginosa., PMID:37188866
Pseudomonas aeruginosa LecB suppresses immune responses by inhibiting transendothelial migration., PMID:36856136
A Fucosylated Lactose-Presenting Tetravalent Glycocluster Acting as a Mutual Ligand of Pseudomonas aeruginosa Lectins A (PA-IL) and B (PA-IIL)-Synthesis and Interaction Studies., PMID:36555839
Neutralizing the Impact of the Virulence Factor LecA from Pseudomonas aeruginosa on Human Cells with New Glycomimetic Inhibitors., PMID:36398566
Discovery of N-β-l-Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecB., PMID:36256875
Lectin-Targeted Prodrugs Activated by Pseudomonas aeruginosa for Self-Destructive Antibiotic Release., PMID:36201248
Characterization of the interaction of multivalent glycosylated ligands with bacterial lectins by biolayer interferometry., PMID:35871443
The Lectin LecB Induces Patches with Basolateral Characteristics at the Apical Membrane to Promote Pseudomonas aeruginosa Host Cell Invasion., PMID:35491830
Structural Considerations for Building Synthetic Glycoconjugates as Inhibitors for Pseudomonas aeruginosa Lectins., PMID:35426976
Neutron crystallography reveals mechanisms used by Pseudomonas aeruginosa for host-cell binding., PMID:35017516
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes., PMID:34985094
Tobramycin-loaded complexes to prevent and disrupt Pseudomonas aeruginosa biofilms., PMID:34841492
Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecA., PMID:34788491
Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins., PMID:33314528
Mannose Conjugated Polymer Targeting P. aeruginosa Biofilms., PMID:33074651
Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosa., PMID:32924479
Modified Galacto- or Fuco-Clusters Exploiting the Siderophore Pathway to Inhibit the LecA- or LecB-Associated Virulence of Pseudomonas aeruginosa., PMID:32701213
LecB, a High Affinity Soluble Fucose-Binding Lectin from Pseudomonas aeruginosa., PMID:32306354
The Pseudomonas aeruginosa Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing., PMID:32156827
Pseudomonas aeruginosa lectin LecB impairs keratinocyte fitness by abrogating growth factor signalling., PMID:31732693
Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors., PMID:31553873
Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Pseudomonas aeruginosa Biofilms., PMID:31449405
Targeting Bacterial Biofilm: A New LecA Multivalent Ligand with Inhibitory Activity., PMID:31216375
Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study., PMID:31146126
The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix., PMID:31097723
Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins., PMID:30837305
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes., PMID:30830745
Expeditious Synthesis of C-Glycosyl Barbiturate Ligands of Bacterial Lectins: From Monomer Design to Glycoclusters and Glycopolymers., PMID:30590917
A Biomimetic Non-Antibiotic Approach to Eradicate Drug-Resistant Infections., PMID:30589118
Screening of a Library of Oligosaccharides Targeting Lectin LecB of Pseudomonas Aeruginosa and Synthesis of High Affinity Oligoglycoclusters., PMID:30477231
Monodisperse Sequence-Controlled α-l-Fucosylated Glycooligomers and Their Multivalent Inhibitory Effects on LecB., PMID:30408344
Tetraphenylethylene-based glycoclusters with aggregation-induced emission (AIE) properties as high-affinity ligands of bacterial lectins., PMID:30403242
Selectivity of original C-hexopyranosyl calix[4]arene conjugates towards lectins of different origin., PMID:30296643
Virtual Screening Against Carbohydrate-Binding Proteins: Evaluation and Application to Bacterial Burkholderia ambifaria Lectin., PMID:30075071
Sub-minimum inhibitory concentrations of ceftazidime inhibit Pseudomonas aeruginosa biofilm formation., PMID:29449129
Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa., PMID:29272578
Perylenediimide-based glycoclusters as high affinity ligands of bacterial lectins: synthesis, binding studies and anti-adhesive properties., PMID:29165489
Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging., PMID:28960731
Photoswitchable Janus glycodendrimer micelles as multivalent inhibitors of LecA and LecB from Pseudomonas aeruginosa., PMID:28858663
Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands., PMID:27412649
Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering β-catenin degradation., PMID:26862060
Pillar[5]arene-Based Glycoclusters: Synthesis and Multivalent Binding to Pathogenic Bacterial Lectins., PMID:26845383
Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene-Containing [2]Rotaxane Scaffold., PMID:26467313
Importance of topology for glycocluster binding to Pseudomonas aeruginosa and Burkholderia ambifaria bacterial lectins., PMID:26412676
Development of a Novel Method for Analyzing Pseudomonas aeruginosa Twitching Motility and Its Application to Define the AmrZ Regulon., PMID:26309248
For research use only. Not for human or drug use.
