Catalog No.
YXX18701
Expression system
E. coli
Species
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Protein length
Ala53-Arg260
Predicted molecular weight
25.59 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55969
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neuraminyllactose-binding hemagglutinin, Flagellar sheath adhesin, N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit, NLBH, hpaA, HP_0797
A potential anti-Helicobacter pylori strategy: Exploring the antibacterial mechanism of organic acids in sea buckthorn (Hippophae rhamnoides L.)., PMID:40073720
Modeling and optimization of culture media for recombinant Helicobacter pylori vaccine antigen HpaA., PMID:39698188
Developing a multi-epitope vaccine against Helicobacter Pylori., PMID:39642777
Association of Antibody Responses to Helicobacter pylori Proteins with Colorectal Adenoma and Colorectal Cancer., PMID:39452767
Candidate Antigens and the Development of Helicobacter pylori Vaccines., PMID:39177204
Real-world evidence of a novel tetravalent immunoglobulin Y effectiveness and safety in patients with the refractory Helicobacter pylori infection., PMID:38937679
Construction and Validation of Chicken Immune scFv Antibody Library against Helicobacter pylori., PMID:38930530
Recombinant L. lactis vaccine LL-plSAM-WAE targeting four virulence factors provides mucosal immunity against H. pylori infection., PMID:38402145
An M cell-targeting recombinant L. lactis vaccine against four H. pylori adhesins., PMID:38396242
Unraveling the crystal structure of the HpaA adhesin: insights into cell adhesion function and epitope localization of a Helicobacter pylori vaccine candidate., PMID:38376163
Embedding of exogenous B cell epitopes on the surface of UreB structure generates a broadly reactive antibody response against Helicobacter pylori., PMID:37899627
A multiserological line assay to potentially discriminate current from past Helicobacter pylori infection., PMID:37827383
Identification and characterization of shark VNARs targeting the Helicobacter pylori adhesin HpaA., PMID:37695066
Helicobacter pylori multiplex serology and risk of non-cardia and cardia gastric cancer: a case-cohort study and meta-analysis., PMID:36913255
Protective immunity enhanced Salmonella vaccine vectors delivering Helicobacter pylori antigens reduce H. pylori stomach colonization in mice., PMID:36466847
Serum antibodies to selected Helicobacter pylori antigens are associated with active gastritis in patients seen at the University Teaching Hospital in Lusaka, Zambia., PMID:37265823
Hesperetin Inhibits Expression of Virulence Factors and Growth of Helicobacter pylori., PMID:34576198
The crosstalk between H. pylori virulence factors and the PD1:PD-L1 immune checkpoint inhibitors in progression to gastric cancer., PMID:34363898
Design, expression, and purification of a multi-epitope vaccine against Helicobacter Pylori based on Melittin as an adjuvant., PMID:34022362
Oral multivalent epitope vaccine, based on UreB, HpaA, CAT, and LTB, for prevention and treatment of Helicobacter pylori infection in C57BL / 6 mice., PMID:33847026
A Novel Multi-Epitopic Peptide Vaccine Candidate Against Helicobacter pylori: In-Silico Identification, Design, Cloning and Validation Through Molecular Dynamics., PMID:33495694
Helicobacter pylori adhesins: HpaA a potential antigen in experimental vaccines for H. pylori., PMID:33259676
Identification of Functional Interactome of Gastric Cancer Cells with Helicobacter pylori Outer Membrane Protein HpaA by HPLC-MS/MS., PMID:32566649
[HpaA promotes gastric mucosa injury via stimulating IL-21 secretion of T cells]., PMID:31638572
[Screening and characterization of nucleic acid aptamers specifically binding to adhesin HpaA from Helicobacter pylori]., PMID:31292058
Synthetic Lipopeptide Enhances Protective Immunity Against Helicobacter pylori Infection., PMID:31258538
Immunoinformatics Approach to Design a Novel Epitope-Based Oral Vaccine Against Helicobacter pylori., PMID:31120321
Epitope-loaded nanoemulsion delivery system with ability of extending antigen release elicits potent Th1 response for intranasal vaccine against Helicobacter pylori., PMID:30660182
Intranasal immunization with immunodominant epitope peptides derived from HpaA conjugated with CpG adjuvant protected mice against Helicobacter pylori infection., PMID:30217524
A survey on chimeric UreB229-561-HpaA protein targeting Helicobacter pylori: Computational and in vitro urease activity valuation., PMID:29929167
Protection Against Helicobacter pylori Infection in BALB/c Mouse Model by Oral Administration of Multivalent Epitope-Based Vaccine of Cholera Toxin B Subunit-HUUC., PMID:29867978
Delivery of Helicobacter pylori HpaA to gastrointestinal mucosal immune sites using Lactococcus lactis and its immune efficacy in mice., PMID:29299716
Performance of a Multiplex Serological Helicobacter pylori Assay on a Novel Microfluidic Assay Platform., PMID:28972560
Immunologic properties and therapeutic efficacy of a multivalent epitope-based vaccine against four Helicobacter pylori adhesins (urease, Lpp20, HpaA, and CagL) in Mongolian gerbils., PMID:28851031
Oral Immunization with a Multivalent Epitope-Based Vaccine, Based on NAP, Urease, HSP60, and HpaA, Provides Therapeutic Effect on H. pylori Infection in Mongolian gerbils., PMID:28824883
Crystallization and X-ray analysis of the extracellular adhesion domain of Helicobacter pylori adhesin A: the significance of the cation composition in the crystallization precipitant., PMID:28368278
Fallacy of the Unique Genome: Sequence Diversity within Single Helicobacter pylori Strains., PMID:28223462
Surface expression of Helicobacter pylori HpaA adhesion antigen on Vibrio cholerae, enhanced by co-expressed enterotoxigenic Escherichia coli fimbrial antigens., PMID:28215587
Systematic identification of immunodominant CD4+ T cell responses to HpaA in Helicobacter pylori infected individuals., PMID:27509059
Construction of a recombinant Lactococcus lactis strain expressing a fusion protein of Omp22 and HpaA from Helicobacter pylori for oral vaccine development., PMID:27406731
Helicobacter pylori blood biomarker for gastric cancer risk in East Asia., PMID:27170766
Cloning, expression and purification flagellar sheath adhesion of Helicobacter pylori in Escherichia coli host as a vaccination target., PMID:26866020
Multiplex-PCR-Based Screening and Computational Modeling of Virulence Factors and T-Cell Mediated Immunity in Helicobacter pylori Infections for Accurate Clinical Diagnosis., PMID:26287606
Anti-Helicobacter pylori Antibody Profiles in Epstein-Barr virus (EBV)-Positive and EBV-Negative Gastric Cancer., PMID:26251258
Oral administration of recombinant Neisseria meningitidis PorA genetically fused to H. pylori HpaA antigen increases antibody levels in mouse serum, suggesting that PorA behaves as a putative adjuvant., PMID:25750999
[The research on the construction and characteristics of recombinant engineering bacteria with multi-epitope of Helicobacter pylori]., PMID:24941798
Helicobacter pylori antibody patterns in Germany: a cross-sectional population study., PMID:24782915
The rOmp22-HpaA fusion protein confers protective immunity against helicobacter pylori in mice., PMID:23715666
A dominant CD4(+) T-cell response to Helicobacter pylori reduces risk for gastric disease in humans., PMID:23232294
Prospective study of Helicobacter pylori biomarkers for gastric cancer risk among Chinese men., PMID:23035179
For research use only. Not for human or drug use.
