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InVivoMAb Anti-Mouse F4/80 & CD3e Bispecific Antibody (Iv0232)

Catalog #:   VMG76701 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG
Applications: FuncS
Accession: Q61549 & P22646
Overview

Catalog No.

VMG76701

Species reactivity

Mouse

Host species

Mouse

Isotype

IgG

Clonality

Monoclonal

Target

Bispecific, Adhesion G protein-coupled receptor E1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor, Adgre1, Emr1, Gpf480, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, Cd3e

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q61549 & P22646

Applications

FuncS

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0232

Data Image
References

HMGB1 Mediates Macrophage Recruitment and Regional Intervertebral Disc Properties Following Injury., PMID:40536102

Bioengineered platelet nanoplatform enables renal-targeted dexamethasone delivery for chronic nephritis therapy with dual anti-inflammatory/anti-fibrotic effects and minimized systemic toxicity., PMID:40535704

Integrated serum pharmacochemistry, network pharmacology and experimental verification to explore the mechanism of Angelicae Pubescentis Radix in the treatment of NASH., PMID:40532987

DHCR7 inhibition ameliorates MetALD and HCC in mice and human 3D liver spheroids., PMID:40529212

Donor macrophage pyroptosis contributes to the development of aGVHD., PMID:40528147

RIPK3-Mediated Necroptosis Drives Macrophage Infiltration and Corneal Neovascularization After Alkali Burn., PMID:40525922

Therapeutic Effects of Fire Needling Acupuncture on Pain Relief and Cartilage Protection in MIA-Induced Knee Osteoarthritis Rats: The Role of Macrophage Polarization in Synovium and Angiogenesis in Subchondral Bone., PMID:40519654

Histone hyperacetylation disrupts spermatogonial stem cells homeostasis and impairs spermiogenesis., PMID:40518506

CDKN1A as a potential target for Eltrombopag treatment in ITP and its regulation of the communication between macrophages and transitional B cells in ITP., PMID:40515824

Multidirectional therapeutic effects of synthesized HMGB1 peptide on liver cirrhosis in mice., PMID:40503100

Recombinant human ADAMTS13 attenuates LPS-induced acute kidney injury and renal microangiopathy in murine advanced liver fibrosis by cleaving vWF., PMID:40499688

EGR2 O-GlcNAcylation orchestrates the development of protumoral macrophages to limit CD8+ T cell antitumor responses., PMID:40499546

Integration analysis of transcriptomics revealed NETosis heterogeneity and Ncf1 as a prognostic biomarker in neutrophil asthma., PMID:40499471

Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation., PMID:40496861

Perineural Invasion Exhibits Traits of Neurodegeneration., PMID:40492439

Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy., PMID:40490137

Design, molecular characterization and therapeutic investigation of a novel CCR8 peptide antagonist that attenuates acute liver injury by inhibiting infiltration and activation of macrophages., PMID:40486848

Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates., PMID:40486518

Treatment with senolytic drugs ameliorates steroid-induced osteonecrosis of the femoral head by inhibiting osteoclastogenesis., PMID:40480005

Short-Chain Fatty Acids Are Potential Biomarkers of Immune Regulation in Diabetic Retinopathy., PMID:40478560

Chromatin Remodeling and Transcriptional Silencing Define the Dynamic Innate Immune Response of Tissue Resident Macrophages After Burn Injury., PMID:40475502

Csf1r⁻ macrophages govern the second wave of neutrophils for bone repair., PMID:40470192

[Mechanism of vanillic acid against cardiac fibrosis induced by isoproterenol in mice based on Drp1/HK1/NLRP3 and mitochondrial apoptosis signaling pathways]., PMID:40461229

SAA1 deletion ameliorates cardiac injury after myocardial infarction by promoting macrophage transformation to reparative subtype., PMID:40460795

Caspase-11 deficiency ameliorates elastase-induced abdominal aortic aneurysm in mice by suppressing inflammatory response of macrophages., PMID:40459928

Apurinic/apyrimidinic endonuclease 1/redox factor-1 deficiency exacerbates renal fibrosis in a unilateral ureteral obstruction model., PMID:40443303

Macrophage depletion in male mice impairs extraction socket healing by disrupting bone regeneration and tissue repair., PMID:40441056

Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing., PMID:40433374

Semaglultide targets Spp1+ microglia/macrophage to attenuate neuroinflammation following perioperative stroke., PMID:40426210

Embryonic mast cells arise from the Cpa3-expressing precursors but not granulocyte-monocyte progenitors., PMID:40419842

[Protective effect and mechanism of hyperbaric oxygen therapy on non-alcoholic fatty liver disease in mice]., PMID:40419372

The axis of miR-30a/AIF-1/TRPC6/calcineurin A/NFAT2 regulated the death modalities and inflammation of renal tubular epithelial cells in diabetic kidney disease via exosome., PMID:40419106

Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis., PMID:40416975

Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation., PMID:40414862

Macrophages Transdifferentiate Into Myofibroblasts During Ocular Surface Inflammation., PMID:40407409

SLP65/SLP76 Csk-interacting membrane protein promotes hepatic ischemia-reperfusion injury by activating TLR4/Erk1/2-mediated macrophages M1 polarization., PMID:40403937

Expression of thrombomodulin in pterygium: implications for inflammation and disease progression., PMID:40397236

Macrophage-derived S100A9 promotes diabetic cardiomyopathy by disturbing mitochondrial quality control via STAT3 activation., PMID:40384874

Cellular effects of splenectomy on liver regeneration after 70% resection., PMID:40376613

GPR40 activation alleviates pulmonary fibrosis by repressing M2 macrophage polarization through the PKD1/CD36/TGF-β1 pathway., PMID:40369224

Magnolia kobus DC. Alleviates adenine-induced chronic kidney disease by regulating ferroptosis in C57BL/6 mice., PMID:40365315

Cellular senescence promotes macrophage-to-myofibroblast transition in chronic ischemic renal disease., PMID:40348745

Pro-inflammatory macrophages contribute to developing comorbid anxiety-like behaviors through gastrointestinal vagal afferent signaling in experimental colitis mice., PMID:40348137

Clusterin ameliorates diabetic atherosclerosis by suppressing macrophage pyroptosis and activation., PMID:40337510

Single-cell RNA sequencing and spatial transcriptomics reveal unique subpopulations of infiltrating macrophages and dendritic cells following AKI., PMID:40331777

Monocytes/macrophages contamination disrupts functional and transcriptional characteristics of murine bone marrow- and bone-derived stromal cells., PMID:40329992

Involvement of the ADAMTS13-von Willebrand factor axis in acute kidney injury in mice with liver cirrhosis., PMID:40318103

Cochlear inflammation in AAV-mediated gene therapy: serotype-dependent macrophage activation and promoter-driven immunogenicity., PMID:40317717

Effect of calcitriol on myeloid-derived suppressor cells in physiological aging., PMID:40316223

Neonatal hypoxia leads to impaired intestinal function and changes in the composition and metabolism of its microbiota., PMID:40312410

Datasheet
$ 484
Product specifications
100 μg 484 1 mg 1932

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For research use only. Not for human or drug use.

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InVivoMAb Anti-Mouse F4/80 & CD3e Bispecific Antibody (Iv0232) [VMG76701]
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