Catalog No.
VMG76701
Species reactivity
Mouse
Host species
Mouse
Isotype
IgG
Clonality
Monoclonal
Target
Bispecific, Adhesion G protein-coupled receptor E1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor, Adgre1, Emr1, Gpf480, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, Cd3e
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q61549 & P22646
Applications
FuncS
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0232
HMGB1 Mediates Macrophage Recruitment and Regional Intervertebral Disc Properties Following Injury., PMID:40536102
Bioengineered platelet nanoplatform enables renal-targeted dexamethasone delivery for chronic nephritis therapy with dual anti-inflammatory/anti-fibrotic effects and minimized systemic toxicity., PMID:40535704
Integrated serum pharmacochemistry, network pharmacology and experimental verification to explore the mechanism of Angelicae Pubescentis Radix in the treatment of NASH., PMID:40532987
DHCR7 inhibition ameliorates MetALD and HCC in mice and human 3D liver spheroids., PMID:40529212
Donor macrophage pyroptosis contributes to the development of aGVHD., PMID:40528147
RIPK3-Mediated Necroptosis Drives Macrophage Infiltration and Corneal Neovascularization After Alkali Burn., PMID:40525922
Therapeutic Effects of Fire Needling Acupuncture on Pain Relief and Cartilage Protection in MIA-Induced Knee Osteoarthritis Rats: The Role of Macrophage Polarization in Synovium and Angiogenesis in Subchondral Bone., PMID:40519654
Histone hyperacetylation disrupts spermatogonial stem cells homeostasis and impairs spermiogenesis., PMID:40518506
CDKN1A as a potential target for Eltrombopag treatment in ITP and its regulation of the communication between macrophages and transitional B cells in ITP., PMID:40515824
Multidirectional therapeutic effects of synthesized HMGB1 peptide on liver cirrhosis in mice., PMID:40503100
Recombinant human ADAMTS13 attenuates LPS-induced acute kidney injury and renal microangiopathy in murine advanced liver fibrosis by cleaving vWF., PMID:40499688
EGR2 O-GlcNAcylation orchestrates the development of protumoral macrophages to limit CD8+ T cell antitumor responses., PMID:40499546
Integration analysis of transcriptomics revealed NETosis heterogeneity and Ncf1 as a prognostic biomarker in neutrophil asthma., PMID:40499471
Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation., PMID:40496861
Perineural Invasion Exhibits Traits of Neurodegeneration., PMID:40492439
Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy., PMID:40490137
Design, molecular characterization and therapeutic investigation of a novel CCR8 peptide antagonist that attenuates acute liver injury by inhibiting infiltration and activation of macrophages., PMID:40486848
Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates., PMID:40486518
Treatment with senolytic drugs ameliorates steroid-induced osteonecrosis of the femoral head by inhibiting osteoclastogenesis., PMID:40480005
Short-Chain Fatty Acids Are Potential Biomarkers of Immune Regulation in Diabetic Retinopathy., PMID:40478560
Chromatin Remodeling and Transcriptional Silencing Define the Dynamic Innate Immune Response of Tissue Resident Macrophages After Burn Injury., PMID:40475502
Csf1r⁻ macrophages govern the second wave of neutrophils for bone repair., PMID:40470192
[Mechanism of vanillic acid against cardiac fibrosis induced by isoproterenol in mice based on Drp1/HK1/NLRP3 and mitochondrial apoptosis signaling pathways]., PMID:40461229
SAA1 deletion ameliorates cardiac injury after myocardial infarction by promoting macrophage transformation to reparative subtype., PMID:40460795
Caspase-11 deficiency ameliorates elastase-induced abdominal aortic aneurysm in mice by suppressing inflammatory response of macrophages., PMID:40459928
Apurinic/apyrimidinic endonuclease 1/redox factor-1 deficiency exacerbates renal fibrosis in a unilateral ureteral obstruction model., PMID:40443303
Macrophage depletion in male mice impairs extraction socket healing by disrupting bone regeneration and tissue repair., PMID:40441056
Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing., PMID:40433374
Semaglultide targets Spp1+ microglia/macrophage to attenuate neuroinflammation following perioperative stroke., PMID:40426210
Embryonic mast cells arise from the Cpa3-expressing precursors but not granulocyte-monocyte progenitors., PMID:40419842
[Protective effect and mechanism of hyperbaric oxygen therapy on non-alcoholic fatty liver disease in mice]., PMID:40419372
The axis of miR-30a/AIF-1/TRPC6/calcineurin A/NFAT2 regulated the death modalities and inflammation of renal tubular epithelial cells in diabetic kidney disease via exosome., PMID:40419106
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis., PMID:40416975
Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation., PMID:40414862
Macrophages Transdifferentiate Into Myofibroblasts During Ocular Surface Inflammation., PMID:40407409
SLP65/SLP76 Csk-interacting membrane protein promotes hepatic ischemia-reperfusion injury by activating TLR4/Erk1/2-mediated macrophages M1 polarization., PMID:40403937
Expression of thrombomodulin in pterygium: implications for inflammation and disease progression., PMID:40397236
Macrophage-derived S100A9 promotes diabetic cardiomyopathy by disturbing mitochondrial quality control via STAT3 activation., PMID:40384874
Cellular effects of splenectomy on liver regeneration after 70% resection., PMID:40376613
GPR40 activation alleviates pulmonary fibrosis by repressing M2 macrophage polarization through the PKD1/CD36/TGF-β1 pathway., PMID:40369224
Magnolia kobus DC. Alleviates adenine-induced chronic kidney disease by regulating ferroptosis in C57BL/6 mice., PMID:40365315
Cellular senescence promotes macrophage-to-myofibroblast transition in chronic ischemic renal disease., PMID:40348745
Pro-inflammatory macrophages contribute to developing comorbid anxiety-like behaviors through gastrointestinal vagal afferent signaling in experimental colitis mice., PMID:40348137
Clusterin ameliorates diabetic atherosclerosis by suppressing macrophage pyroptosis and activation., PMID:40337510
Single-cell RNA sequencing and spatial transcriptomics reveal unique subpopulations of infiltrating macrophages and dendritic cells following AKI., PMID:40331777
Monocytes/macrophages contamination disrupts functional and transcriptional characteristics of murine bone marrow- and bone-derived stromal cells., PMID:40329992
Involvement of the ADAMTS13-von Willebrand factor axis in acute kidney injury in mice with liver cirrhosis., PMID:40318103
Cochlear inflammation in AAV-mediated gene therapy: serotype-dependent macrophage activation and promoter-driven immunogenicity., PMID:40317717
Effect of calcitriol on myeloid-derived suppressor cells in physiological aging., PMID:40316223
Neonatal hypoxia leads to impaired intestinal function and changes in the composition and metabolism of its microbiota., PMID:40312410