Catalog No.
VHB86903
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG
Clonality
Monoclonal
Target
Bispecific, Epidermal growth factor receptor, 2.7.10.1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, Cd3e
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P00533 & P22646
Applications
FuncS
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0228
Synthesis, In Vitro Evaluation, and Molecular Docking Studies of Novel 3,5-Diphenyl-1H-1,2,4-Triazole Derivatives as Potential hEGFR Inhibitors., PMID:40359331
[Novel Therapy Targeting the Cancer Microenvironment Using Near-Infrared Photoimmunotherapy Leading to Tumor Immune Activation]., PMID:38303275
Influence of renal function on the ability of TyG Index to predict all-cause mortality., PMID:37951945
BCA101 Is a Tumor-Targeted Bifunctional Fusion Antibody That Simultaneously Inhibits EGFR and TGFβ Signaling to Durably Suppress Tumor Growth., PMID:37074042
Design and synthesis of new heterocyclic compounds containing 5-[(1H-1,2,4-triazol-1-yl)methyl]-3H-1,2,4-triazole-3-thione structure as potent hEGFR inhibitors., PMID:36688370
Potential of Epidermal Growth Factor-like Peptide from the Sea Cucumber Stichopus horrens to Increase the Growth of Human Cells: In Silico Molecular Docking Approach., PMID:36286420
Optimal Light Dose for hEGFR-Targeted Near-Infrared Photoimmunotherapy., PMID:36011036
Defucosylated Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Exerted Antitumor Activities in Mouse Xenograft Models of Canine Mammary Gland Tumor., PMID:35666554
Antitumor Activities in Mouse Xenograft Models of Canine Mammary Gland Tumor by Defucosylated Mouse-Dog Chimeric Anti-Epidermal Growth Factor Receptor Antibody (E134Bf)., PMID:35471048
Antitumor Activities in Mouse Xenograft Models of Canine Fibroblastic Tumor by Defucosylated Anti-Epidermal Growth Factor Receptor Monoclonal Antibody., PMID:35377239
Defucosylated Anti-Epidermal Growth Factor Receptor Monoclonal Antibody (134-mG2a-f) Exerts Antitumor Activities in Mouse Xenograft Models of Canine Osteosarcoma., PMID:35225663
Selection of antibody and light exposure regimens alters therapeutic effects of EGFR-targeted near-infrared photoimmunotherapy., PMID:35013765
Defucosylated Mouse-Dog Chimeric Anti-EGFR Antibody Exerts Antitumor Activities in Mouse Xenograft Models of Canine Tumors., PMID:34944112
Simultaneously Combined Cancer Cell- and CTLA4-Targeted NIR-PIT Causes a Synergistic Treatment Effect in Syngeneic Mouse Models., PMID:34518299
Defucosylated Anti-Epidermal Growth Factor Receptor Monoclonal Antibody 134-mG2a-f Exerts Antitumor Activities in Mouse Xenograft Models of Dog Epidermal Growth Factor Receptor-Overexpressed Cells., PMID:34424762
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials., PMID:33933782
Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence-Activated Cell Sorting., PMID:32914549
How Early Postoperative Urinary Tract Infections Affect Renal Graft Function at 1-Year Follow-up., PMID:32482447
Epi-drugs as triple-negative breast cancer treatment., PMID:32396394
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor., PMID:31752491
Functional comparison of the human epidermal growth factor receptor and telomerase reverse transcriptase promoters in canine tumor cells., PMID:30674742
Oriented immobilization to nanoparticles enhanced the therapeutic efficacy of antibody drugs., PMID:30641288
Predictors of systemic therapy sequences following a CDK 4/6 inhibitor-based regimen in post-menopausal women with hormone receptor positive, HEGFR-2 negative metastatic breast cancer., PMID:30175631
Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer., PMID:28151706
EGFR-Stat3 signalling in nerve glial cells modifies neurofibroma initiation., PMID:27748759
The combined EGFR protein expression analysis refines the prognostic value of the MGMT promoter methylation status in glioblastoma., PMID:27450763
Development and use of specific ELISA methods for quantifying the biological activity of bevacizumab, cetuximab and trastuzumab in stability studies., PMID:27296731
pH dependence of ligand-induced human epidermal growth factor receptor activation investigated by molecular dynamics simulations., PMID:27179806
Combined epidermal growth factor receptor and Beclin1 autophagic protein expression analysis identifies different clinical presentations, responses to chemo- and radiotherapy, and prognosis in glioblastoma., PMID:25821789
Targeted in vivo photodynamic therapy with epidermal growth factor receptor-specific peptide linked nanoparticles., PMID:24939618
Gold nanoparticle modified capacitive sensor platform for multiple marker detection., PMID:24274298
Targeted antiepidermal growth factor receptor (cetuximab) immunoliposomes enhance cellular uptake in vitro and exhibit increased accumulation in an intracranial model of glioblastoma multiforme., PMID:24175095
A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer., PMID:23993964
Ligand binding and dynamics of the monomeric epidermal growth factor receptor ectodomain., PMID:23760854
An in vivo C. elegans model system for screening EGFR-inhibiting anti-cancer drugs., PMID:22957020
Correlation between EGFr expression and accelerated proliferation during radiotherapy of head and neck squamous cell carcinoma., PMID:22920680
Inhibition of cell proliferation by an anti-EGFR aptamer., PMID:21687663
Combinational RNAi gene therapy of hepatocellular carcinoma by targeting human EGFR and TERT., PMID:21238587
The NMR solution structure of human epidermal growth factor (hEGF) at physiological pH and its interactions with suramin., PMID:21029725
A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro., PMID:20807764
Mutations of epidermal growth factor receptor in colon cancer indicate susceptibility or resistance to gefitinib., PMID:18497962
A functional role for EGFR signaling in myelination and remyelination., PMID:17618276
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies., PMID:16730237
Perinatal epidermal growth factor receptor blockade prevents peripheral nerve disruption in a mouse model reminiscent of benign world health organization grade I neurofibroma., PMID:16651634
[Construction and expression of siRNA expression constructs targeting epidermal growth factor receptor]., PMID:15793774
[Inhibitory effects of siRNA targeting epidermal growth factor receptor on proliferation and invasion of human glioblastoma cells]., PMID:15500708
Expression patterns of epidermal growth factor receptor and fibroblast growth factor receptor 1 mRNA in fetal human brain., PMID:12794748
Enzyme immunoassay of human epidermal growth factor receptor (hEGFR)., PMID:11847425
Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain., PMID:11467954
Characterization of a recombinant monoclonal antibody by mass spectrometry combined with liquid chromatography., PMID:11270865
For research use only. Not for human or drug use.
