Catalog No.
EMN45101
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Leu64-Ser223
Predicted molecular weight
46.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P27812
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Killer cell lectin-like receptor subfamily B member 1B allele A, CD161 antigen-like family member B, Lymphocyte antigen 55b, Ly-55b, NKR-P1 34, Natural killer cell surface protein NKR-P1B allele SJL/BALB, NKR-P1B, CD161b, Klrb1b, Ly55b, Nkrp1b
The inhibitory NKR-P1B receptor regulates NK cell-mediated mammary tumor immunosurveillance in mice., PMID:36704449
Mouse Cytomegalovirus m153 Protein Stabilizes Expression of the Inhibitory NKR-P1B Ligand Clr-b., PMID:31597762
NKR-P1B expression in gut-associated innate lymphoid cells is required for the control of gastrointestinal tract infections., PMID:30275537
Frontline Science: A hyporesponsive subset of rat NK cells negative for Ly49s3 and NKR-P1B are precursors to the functionally mature NKR-P1B+ subset., PMID:28747319
A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family., PMID:28340350
Interferon-Dependent Induction of Clr-b during Mouse Cytomegalovirus Infection Protects Bystander Cells from Natural Killer Cells via NKR-P1B-Mediated Inhibition., PMID:28288457
Expansion and Protection by a Virus-Specific NK Cell Subset Lacking Expression of the Inhibitory NKR-P1B Receptor during Murine Cytomegalovirus Infection., PMID:27511735
Recombinant expression, in vitro refolding and characterizing disulfide bonds of a mouse inhibitory C-type lectin-like receptor Nkrp1b., PMID:26447598
Genetic investigation of MHC-independent missing-self recognition by mouse NK cells using an in vivo bone marrow transplantation model., PMID:25681346
The mouse NKR-P1B:Clr-b recognition system is a negative regulator of innate immune responses., PMID:25612621
Functional characterization of a conserved pair of NKR-P1 receptors expressed by NK cells and T lymphocytes in liver and gut., PMID:25382546
Aberrant Pregnancy Adaptations in the Peripheral Immune Response in Type 1 Diabetes: A Rat Model., PMID:23805184
Mouse Nkrp1-Clr gene cluster sequence and expression analyses reveal conservation of tissue-specific MHC-independent immunosurveillance., PMID:23226525
Poxvirus infection-associated downregulation of C-type lectin-related-b prevents NK cell inhibition by NK receptor protein-1B., PMID:22491247
Two complementary rat NK cell subsets, Ly49s3+ and NKR-P1B+, differ in phenotypic characteristics and responsiveness to cytokines., PMID:20395458
Cytomegalovirus evasion of innate immunity by subversion of the NKR-P1B:Clr-b missing-self axis., PMID:17462921
Comblike dendrimers containing Tn antigen modulate natural killing and induce the production of Tn specific antibodies., PMID:17034145
Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells., PMID:16751398
Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors., PMID:14990792
Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors., PMID:12858173
Expression cloning and function of the rat NK activating and inhibitory receptors NKR-P1A and -P1B., PMID:12618485
Analysis of a 1-Mb BAC contig overlapping the mouse Nkrp1 cluster of genes: cloning of three new Nkrp1 members, Nkrp1d, Nkrp1e, and Nkrp1f., PMID:11685472
NKR-P1dim/TCR alpha beta + T cells and natural killer cells share expression of NKR-P1A and NKR-P1D., PMID:9390275
For research use only. Not for human or drug use.
