Catalog No.
EVV32901
Expression system
Mammalian Cells
Species
Suid alphaherpesvirus 1 (PRV)
Protein length
Ala18-Val355
Predicted molecular weight
41.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q80KC8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GD, Glycoprotein D, US6
Vimentin as a universal receptor for pseudorabies virus infection in pig and human cells., PMID:39549807
Immune Responses Induced by a Recombinant Lactiplantibacillus plantarum Surface-Displaying the gD Protein of Pseudorabies Virus., PMID:39205163
A Single Amino Acid Substitution in the Transmembrane Domain of Glycoprotein H Functionally Compensates for the Absence of gL in Pseudorabies Virus., PMID:38257727
Pseudorabies gD protein protects mice and piglets against lethal doses of pseudorabies virus., PMID:38029147
The mutations on the envelope glycoprotein D contribute to the enhanced neurotropism of the pseudorabies virus variant., PMID:37838171
Association of THBS3 with Glycoprotein D Promotes Pseudorabies Virus Attachment, Fusion, and Entry., PMID:36648234
A poly(dimethylsiloxane)-based solid-phase microchip platform for dual detection of Pseudorabies virus gD and gE antibodies., PMID:35959367
Isolation and Characterization of Two Pseudorabies Virus and Evaluation of Their Effects on Host Natural Immune Responses and Pathogenicity., PMID:35458442
Alphaherpesvirus-induced activation of plasmacytoid dendritic cells depends on the viral glycoprotein gD and is inhibited by non-infectious light particles., PMID:34843605
A Genome-Wide CRISPR/Cas9 Screen Reveals the Requirement of Host Sphingomyelin Synthase 1 for Infection with Pseudorabies Virus Mutant gD-Pass., PMID:34452438
A monoclonal antibody neutralizes pesudorabies virus by blocking gD binding to the receptor nectin-1., PMID:34339791
Immunogenicity and protective efficacy induced by an mRNA vaccine encoding gD antigen against pseudorabies virus infection., PMID:33129042
Functional Relevance of the Transmembrane Domain and Cytoplasmic Tail of the Pseudorabies Virus Glycoprotein H for Membrane Fusion., PMID:29618646
Structural basis of nectin-1 recognition by pseudorabies virus glycoprotein D., PMID:28542478
Comparison of different prime-boost regimes with DNA and recombinant Orf virus based vaccines expressing glycoprotein D of pseudorabies virus in pigs., PMID:20018271
DNA priming and killed virus boosting vaccination strategy can augment the immune response to pseudorabies virus., PMID:18076306
In vivo tissue distribution and kinetics of a pseudorabies virus plasmid DNA vaccine after intramuscular injection in swine., PMID:17728026
Glycoprotein D-independent spread of pseudorabies virus infection in cultured peripheral nervous system neurons in a compartmented system., PMID:17652377
Alpha-herpesvirus glycoprotein D interaction with sensory neurons triggers formation of varicosities that serve as virus exit sites., PMID:16831884
A DNA vaccine coding for gB and gD of pseudorabies virus (suid herpes type 1) primes the immune system in the presence of maternal immunity more efficiently than conventional vaccines., PMID:16289276
Pseudorabies virus glycoprotein gD contains a functional endocytosis motif that acts in concert with an endocytosis motif in gB to drive internalization of antibody-antigen complexes from the surface of infected monocytes., PMID:15890963
Use of herpes simplex virus and pseudorabies virus chimeric glycoprotein D molecules to identify regions critical for membrane fusion., PMID:15583135
Novel recombinant parapoxvirus vectors induce protective humoral and cellular immunity against lethal herpesvirus challenge infection in mice., PMID:12915547
[Cloning and expression of the envelope glycoprotein gD gene of pseudorabies virus EA strain]., PMID:12549087
Protective antiviral immune responses to pseudorabies virus induced by DNA vaccination using dimethyldioctadecylammonium bromide as an adjuvant., PMID:12239334
In vivo egress of an alphaherpesvirus from axons., PMID:12134036
Disruption of adherens junctions liberates nectin-1 to serve as receptor for herpes simplex virus and pseudorabies virus entry., PMID:12072519
Glycoprotein D-independent infectivity of pseudorabies virus results in an alteration of in vivo host range and correlates with mutations in glycoproteins B and H., PMID:11581374
Use of chimeric nectin-1(HveC)-related receptors to demonstrate that ability to bind alphaherpesvirus gD is not necessarily sufficient for viral entry., PMID:11437670
Prothymosin alpha enhances protective immune responses induced by oral DNA vaccination against pseudorabies delivered by Salmonella choleraesuis., PMID:11427270
Vaccination of pigs with a recombinant porcine adenovirus expressing the gD gene from pseudorabies virus., PMID:11395210
Porcine HveC, a member of the highly conserved HveC/nectin 1 family, is a functional alphaherpesvirus receptor., PMID:11277703
Glycoprotein D homologs in herpes simplex virus type 1, pseudorabies virus, and bovine herpes virus type 1 bind directly to human HveC(nectin-1) with different affinities., PMID:11162814
Role of the cytoplasmic tail of pseudorabies virus glycoprotein E in virion formation., PMID:10756012
Role of the cytoplasmic tails of pseudorabies virus glycoproteins B, E and M in intracellular localization and virion incorporation., PMID:11125174
Pseudorabies virus glycoprotein M inhibits membrane fusion., PMID:10888614
Single inoculation of replication-defective adenovirus-vectored vaccines at birth in piglets with maternal antibodies induces high level of antibodies and protection against pseudorabies., PMID:10699321
Role of anti-gB and -gD antibodies in antibody-induced endocytosis of viral and cellular cell surface glycoproteins expressed on pseudorabies virus-infected monocytes., PMID:10662611
Infection of Chinese hamster ovary cells by pseudorabies virus., PMID:10482550
The murine homolog (Mph) of human herpesvirus entry protein B (HveB) mediates entry of pseudorabies virus but not herpes simplex virus types 1 and 2., PMID:10196354
Vaccination of pigs against pseudorabies virus with plasmid DNA encoding glycoprotein D., PMID:10195639
Development of porcine adenovirus-3 as an expression vector., PMID:10091994
Infectivity of a pseudorabies virus mutant lacking attachment glycoproteins C and D., PMID:9696830
Role of envelope protein gE endocytosis in the pseudorabies virus life cycle., PMID:9573220
DNA vaccination induces a long-term antibody response and protective immunity against pseudorabies virus in mice., PMID:9505970
Vaccination with recombinant vaccinia virus vaccines expressing glycoprotein genes of pseudorabies virus in the presence of maternal immunity., PMID:9453121
Biologically safe, non-transmissible pseudorabies virus vector vaccine protects pigs against both Aujeszky's disease and classical swine fever., PMID:9400982
Effective priming of neonates born to immune dams against the immunogenic pseudorabies virus glycoprotein gD by replication-incompetent adenovirus-mediated gene transfer at birth., PMID:9400981
Efficacy of replication-defective adenovirus-vectored vaccines: protection following intramuscular injection is linked to promoter efficiency in muscle representative cells., PMID:9400605
Protection of pigs against Aujeszky's disease by DNA vaccination., PMID:9291999
For research use only. Not for human or drug use.
