Catalog No.
EVV35301
Expression system
Insect Cells
Species
BK polyomavirus (strain AS) (BKPyV)
Protein length
Met1-Val362
Predicted molecular weight
41.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14996
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Major capsid protein VP1, Major structural protein VP1
Development of a urinary antigen test for BK Polyomavirus to help clinicians in patients' follow-up., PMID:39909081
Heterologous immunization strategy developed broadly reactive human monoclonal antibodies against the BK virus., PMID:39763742
Nonclinical and clinical characterization of MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK polyomavirus VP1., PMID:38996969
Structural implications of BK polyomavirus sequence variations in the major viral capsid protein Vp1 and large T-antigen: a computational study., PMID:38501831
Time-dependent variations in BK polyomavirus genome from kidney transplant recipients with persistent viremia., PMID:37598256
Lessons from Polyomavirus Immunofluorescence Staining of Urinary Decoy Cells., PMID:37511901
The role of the DE and EF loop of BKPyV VP1 in the serological cross-reactivity between subtypes., PMID:36587871
Quantification of APOBEC3 Mutation Rates Affecting the VP1 Gene of BK Polyomavirus In Vivo., PMID:36146883
BK virus-specific T cells for immunotherapy of progressive multifocal leukoencephalopathy: an open-label, single-cohort pilot study., PMID:34302788
Prospective investigation of polyomavirus infection and the risk of adult glioma., PMID:33953301
BKTyper: Free Online Tool for Polyoma BK Virus VP1 and NCCR Typing., PMID:32751885
Glibenclamide inhibits BK polyomavirus infection in kidney cells through CFTR blockade., PMID:32229236
A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses., PMID:31960795
BK Virus Replication in the Glomerular Vascular Unit: Implications for BK Virus Associated Nephropathy., PMID:31252545
Characterization of BK Polyomaviruses from Kidney Transplant Recipients Suggests a Role for APOBEC3 in Driving In-Host Virus Evolution., PMID:29746834
Different Strains of BK Polyomavirus: VP1 Sequences in a Group of Iranian Prostate Cancer Patients., PMID:29277885
Clinically Relevant Reactivation of Polyomavirus BK (BKPyV) in HLA-A02-Positive Renal Transplant Recipients Is Associated with Impaired Effector-Memory Differentiation of BKPyV-Specific CD8+ T Cells., PMID:27723787
Definition and characterization of novel HLA-*A02-restricted CD8+ T cell epitopes derived from JCV polyomavirus with clinical relevance., PMID:27705933
BK virus encephalopathy and sclerosing vasculopathy in a patient with hypohidrotic ectodermal dysplasia and immunodeficiency., PMID:27411570
Comparative evaluation of laboratory developed real-time PCR assays and RealStar(®) BKV PCR Kit for quantitative detection of BK polyomavirus., PMID:27091098
Interaction between Simian Virus 40 Major Capsid Protein VP1 and Cell Surface Ganglioside GM1 Triggers Vacuole Formation., PMID:27006465
New Structural Insights into the Genome and Minor Capsid Proteins of BK Polyomavirus using Cryo-Electron Microscopy., PMID:26996963
Broadly neutralizing human monoclonal JC polyomavirus VP1-specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy., PMID:26400911
Commercially available immunoglobulins contain virus neutralizing antibodies against all major genotypes of polyomavirus BK., PMID:25736704
Seroprevalence rates of BKV, JCV, and MCPyV polyomaviruses in the general Czech Republic population., PMID:24214630
A structure-guided mutation in the major capsid protein retargets BK polyomavirus., PMID:24130487
An in-house assay for BK polyomavirus quantification using the Abbott m2000 RealTime system., PMID:23924663
Phenotypic and functional characterization of circulating polyomavirus BK VP1-specific CD8+ T cells in healthy adults., PMID:23864628
Antigen-specific T cell responses to BK polyomavirus antigens identify functional anti-viral immunity and may help to guide immunosuppression following renal transplantation., PMID:21671906
Polymorphisms of the BK virus subtypes and their influence on viral in vitro growth efficiency., PMID:20138933
BK virus has tropism for human salivary gland cells in vitro: implications for transmission., PMID:19782382
Mutations in the external loops of BK virus VP1 and urine viral load in renal transplant recipients., PMID:19780025
Quantitation of human seroresponsiveness to Merkel cell polyomavirus., PMID:19750217
Genotyping schemes for polyomavirus BK, using gene-specific phylogenetic trees and single nucleotide polymorphism analysis., PMID:19109389
Early events during BK virus entry and disassembly., PMID:19036822
Mutations in the BC-loop of the BKV VP1 region do not influence viral load in renal transplant patients., PMID:19031459
Biologic diversity of polyomavirus BK genomic sequences: Implications for molecular diagnostic laboratories., PMID:18712842
Functional characterization of BK virus-specific CD4+ T cells with cytotoxic potential in seropositive adults., PMID:17931108
Identification of amino acid residues in BK virus VP1 that are critical for viability and growth., PMID:17699578
Oncogenic potentials of the human polyomavirus regulatory proteins., PMID:17483871
Virus-like particles derived from major capsid protein VP1 of different polyomaviruses differ in their ability to induce maturation in human dendritic cells., PMID:16904154
Evolution of BK virus based on complete genome data., PMID:16897259
Serological diagnosis of human polyomavirus infection., PMID:16626030
Cross-reactive CTL recognizing two HLA-A*02-restricted epitopes within the BK virus and JC virus VP1 polypeptides are frequent in immunocompetent individuals., PMID:16600320
Interplay of cellular and humoral immune responses against BK virus in kidney transplant recipients with polyomavirus nephropathy., PMID:16537617
Unique BK virus non-coding control region (NCCR) variants in hematopoietic stem cell transplant recipients with and without hemorrhagic cystitis., PMID:16482558
Stability of the BK polyomavirus genome in renal-transplant patients without nephropathy., PMID:16432015
Polymorphism in the genome of non-passaged human polyomavirus BK: implications for cell tropism and the pathological role of the virus., PMID:15629766
Characterization of self-assembled virus-like particles of human polyomavirus BK generated by recombinant baculoviruses., PMID:12832209
Seroepidemiology of the human polyomaviruses., PMID:12771419
For research use only. Not for human or drug use.
