Anti-Human PAPPA Monoclonal Antibody (1A407)

Catalog No.

MHG44702

Species reactivity

Human

Host species

Mouse

Isotype

IgG

Clonality

Monoclonal

Immunogen

Human PAPPA Protein.

Target

Pappalysin-1, 3.4.24.79, Insulin-like growth factor-dependent IGF-binding protein 4 protease, IGF-dependent IGFBP-4 protease, IGFBP-4ase, Pregnancy-associated plasma protein A, PAPP-A, PAPPA

Concentration

1mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

1A407

Unraveling Venetoclax Resistance: Navigating the Future of HMA/Venetoclax-Refractory AML in the Molecular Era., PMID:40361510

Automatic Single-Cell Harvesting for Fetal Nucleated Red Blood Cell Isolation on a Self-Assemble Cell Array (SACA) Chip., PMID:39770268

Dual Immune Checkpoint Inhibition in Patients With Aggressive Thyroid Carcinoma: A Phase 2 Nonrandomized Clinical Trial., PMID:39446365

Risk stratification analysis of recurrent myocardial infarction in Indian population using inflammatory, lipid, thrombotic and extracellular matrix remodeling markers., PMID:39351476

Clinical efficacy and autoantibody seroconversion with CD19-CAR T cell therapy in a patient with rheumatoid arthritis and coexisting myasthenia gravis., PMID:38937071

Serum hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein A but does not serve as an independent marker for preeclampsia†., PMID:38780059

PAPP-A as a Potential Target in Thyroid Eye Disease., PMID:38752390

Characterization of immortalized ovarian epithelial cells with BRCA1/2 mutation., PMID:38615309

Dynamics of Anti-SARS-CoV-2 IgA and IgG Responses and Their Protective Effect against Fatal Disease after Booster COVID-19 Vaccination., PMID:38276671

Genetic and Pharmacological Inhibition of PAPP-A Reduces Bleomycin-Induced Pulmonary Fibrosis in Aged Mice via Reduced IGF Signaling., PMID:40110162

Clinical Application of a Graphene Oxide-Based Surface Plasmon Resonance Biosensor to Measure First-Trimester Serum Pregnancy-Associated Plasma Protein-A/A2 Ratio to Predict Preeclampsia., PMID:38090367

A randomized clinical trial of bermekimab treatment for clinical improvement of systemic sclerosis., PMID:37680472

High levels of hemolysis do not affect measurement of PAPP-A, β-HCG and TRAb on BRAHMS KRYPTOR compact plus., PMID:37458499

Augmented oxidative stress, accumulation of DNA damage and impaired DNA repair mechanisms in thrombotic primary antiphospholipid syndrome., PMID:37454866

Effect of body mass index on treatment response of biologic/targeted-synthetic DMARDs in patients with rheumatoid arthritis, psoriatic arthritis or axial spondyloarthritis. A systematic review., PMID:37150489

Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn's Disease: A Pragmatic Randomized Trial., PMID:37004887

Immunogenicity of a third dose of the BNT162b2 COVID-19 vaccine in patients with CLL: effects on treatment selection., PMID:36271935

Intensity of Humoral Immune Responses, Adverse Reactions, and Post-Vaccination Morbidity after Adenovirus Vector-Based and mRNA Anti-COVID-19 Vaccines., PMID:36016156

Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists., PMID:35876840

Pharmacogenetic analysis of canonical versus noncanonical pathway of NF-kB in Crohn's disease patients under anti-tumor necrosis factor-α treatment., PMID:35852914

Ibrutinib plus Bendamustine and Rituximab in Untreated Mantle-Cell Lymphoma., PMID:35657079

Safety and immunogenicity of the BNT162b2 mRNA Covid-19 vaccine in patients with chronic lymphocytic leukemia: a prospective study., PMID:35646300

Utilization of Antitumor Necrosis Factor Biologics in Very Early Onset Inflammatory Bowel Disease: A Multicenter Retrospective Cohort Study From North America., PMID:35622080

Selection of early pregnancy specific proteins and development a rapid immunochromatographic test strip in cows., PMID:35567990

Real-life Experience With Rituximab-CHOP Every 21 or 14 Days in Primary Mediastinal Large B-cell Lymphoma., PMID:35478115

Characterizing Kinetics and Avidity of SARS-CoV-2 Antibody Responses in COVID-19 Greek Patients., PMID:35458488

Oxidative stress and endogenous DNA damage in blood mononuclear cells may predict anti-SARS-CoV-2 antibody titers after vaccination in older adults., PMID:35314351

Red Blood Cell Abnormalities as the Mirror of SARS-CoV-2 Disease Severity: A Pilot Study., PMID:35126186

Pregnancy-associated plasma protein-A (PAPP-A) is a key component of an interactive cellular mechanism promoting pulmonary fibrosis., PMID:35098542

Dual Mode Sensing of Binding and Blocking of Cancer Exosomes to Biomimetic Human Primary Stem Cell Surfaces., PMID:34802228

Kinetics of Nucleocapsid, Spike and Neutralizing Antibodies, and Viral Load in Patients with Severe COVID-19 Treated with Convalescent Plasma., PMID:34578426

Treatment of severe atopic dermatitis and eosinophilic esophagitis with dupilumab in a 14-year-old boy with autosomal dominant hyper-IgE syndrome., PMID:34280586

Multicentric EORTC retrospective study shows efficacy of brentuximab vedotin in patients who have mycosis fungoides and Sézary syndrome with variable CD30 positivity., PMID:34137025

Effective DNA damage response after acute but not chronic immune challenge: SARS-CoV-2 vaccine versus Systemic Lupus Erythematosus., PMID:34089859

SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma donors., PMID:34053848

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial., PMID:34000257

A Phase II Study on the Use of Convalescent Plasma for the Treatment of Severe COVID-19- A Propensity Score-Matched Control Analysis., PMID:33920489

Identification of Very Low-Risk Subgroups of Patients with Primary Mediastinal Large B-Cell Lymphoma Treated with R-CHOP., PMID:33870594

Real-life experience with the combination of polatuzumab vedotin, rituximab, and bendamustine in aggressive B-cell lymphomas., PMID:33583077

Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells., PMID:33561324

First trimester combined screening test for aneuploidies in anti-Ro carriers pregnant women., PMID:33559011

Positron emission tomography after response to rituximab-CHOP in primary mediastinal large B-cell lymphoma: impact on outcomes and radiotherapy strategies., PMID:33523289

Are psychiatric disorders associated with thyroid hormone therapy in adolescents and young adults with type 1 diabetes?, PMID:33325120

Anti-SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical Study., PMID:33260775

Association Between DNA Damage Response, Fibrosis and Type I Interferon Signature in Systemic Sclerosis., PMID:33123169

Genetic and Pharmacological Inhibition of PAPP-A Protects Against Visceral Obesity in Mice., PMID:32888014

West Nile virus in humans, Greece, 2018: the largest seasonal number of cases, 9 years after its emergence in the country., PMID:32794446

Aberrant pregnancy-associated plasma protein-A expression in breast cancers prognosticates clinical outcomes., PMID:32792532

Postpartum Follow-Up of Women Who Developed Subclinical Hypothyroidism during Pregnancy., PMID:32756301

Biomarkers Associated With Aortic Valve Calcification: Should We Focus on Sex Specific Processes?, PMID:32754594

Document Download

Anti-Human PAPPA Monoclonal Antibody (1A407).pdf