Catalog No.
MHD84402
Species reactivity
Human
Host species
Mouse
Isotype
IgG
Clonality
Monoclonal
Immunogen
Human SCCA Protein.
Target
Serpin B3, Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1, SERPINB3, SCCA, SCCA1, Serpin B4, Leupin, Peptidase inhibitor 11, PI-11, Squamous cell carcinoma antigen 2, SCCA-2, SERPINB4, PI11, SCCA2
Concentration
1mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
1A294
Advances in Cervical Cancer Diagnostics Based on Immunosensors: Innovative Approaches and Tumor Biomarkers., PMID:40192049
Ultrasensitive detection of SCCA employing a graphene oxide integrated microfiber ring laser biosensor., PMID:39276440
Progress in the treatment of anal cancer: an overview of the latest investigational drugs., PMID:38275174
First-in-human phase I/Ib study of NIZ985, a recombinant heterodimer of IL-15 and IL-15Rα, as a single agent and in combination with spartalizumab in patients with advanced and metastatic solid tumors., PMID:37907221
Impact of anti-squamous cell carcinoma antigen antibodies on serum squamous cell carcinoma antigen levels measured by chemiluminescent immunoassay and chemiluminescent enzyme immunoassay., PMID:37706549
Panitumumab in combination with chemoradiotherapy for the treatment of locally-advanced anal canal carcinoma: Results of the FFCD 0904 phase II trial., PMID:37315583
Photoelectrochemical immunoassay of squamous cell carcinoma antigen based on CuO/nitrogen-doped porous carbon-ZnO biolabeling and a type-II In2O3/AgBiS2 heterojunction., PMID:37099090
β-Cyclodextrin-functionalized Ti3C2Tx MXene nanohybrids as innovative signal amplifiers for the electrochemical sandwich-like immunosensing of squamous cell carcinoma antigen., PMID:36810629
Bile detection of squamous cell carcinoma antigen (SCCA) in extrahepatic cholangiocarcinoma., PMID:36369195
First-in-human study of an OX40 (ivuxolimab) and 4-1BB (utomilumab) agonistic antibody combination in patients with advanced solid tumors., PMID:36302562
Ultrasensitive sandwich-typed electrochemical immunoassay for detection of squamous cell carcinoma antigen based on highly branched PtCo nanocrystals and dendritic mesoporous SiO2@AuPt nanoparticles., PMID:36219254
The Effect of Microwave Ablation Combined with Anti-PD-1 Monoclonal Antibody on T Cell Subsets and Long-Term Prognosis in Patients Suffering from Non-Small-Cell Lung Cancer., PMID:36199771
A microfluidic chip using Au@SiO2 array-based highly SERS-active substrates for ultrasensitive detection of dual cervical cancer-related biomarkers., PMID:36050486
Efficacy of autoantibodies combined with tumor markers in the detection of lung cancer., PMID:35596744
A sandwich SERS immunoassay platform based on a single-layer Au-Ag nanobox array substrate for simultaneous detection of SCCA and survivin in serum of patients with cervical lesions., PMID:35494344
Combination of squamous cell carcinoma antigen immunocomplex and alpha-fetoprotein in mid- and long-term prediction of hepatocellular carcinoma among cirrhotic patients., PMID:35068873
Current treatment and future directions in the management of anal cancer., PMID:34847242
A novel lanthanide-based NIR-II nanoprobe for lung squamous cell carcinoma identification., PMID:34582537
Emerging and Experimental Agents for Anal Cancer: What is New?, PMID:33859504
SCCA-IgM in hepatocellular carcinoma patients treated with transarterial chemoembolization: gender-related differences., PMID:32808827
Outcomes with anti-EGFR monoclonal antibodies in metastatic and recurrent anal squamous cell carcinoma., PMID:32799569
The simultaneous detection of the squamous cell carcinoma antigen and cancer antigen 125 in the cervical cancer serum using nano-Ag polydopamine nanospheres in an SERS-based lateral flow immunoassay., PMID:35521095
Immunotherapy in Anal Cancer., PMID:32651760
Atezolizumab plus modified docetaxel-cisplatin-5-fluorouracil (mDCF) regimen versus mDCF in patients with metastatic or unresectable locally advanced recurrent anal squamous cell carcinoma: a randomized, non-comparative phase II SCARCE GERCOR trial., PMID:32334548
Synergistic amplification effect for electrochemiluminescence immunoassay based on dual coreactants coupling with resonance energy transfer., PMID:32113560
Squamous cell carcinoma antigen-IgM (SCCA-IgM) is associated with interstitial lung disease in systemic sclerosis., PMID:32087361
Serum Squamous Cell Carcinoma Antigen-Immunoglobulin M complex levels predict survival in patients with cirrhosis., PMID:31882893
Elevating performance of electrochemical immunosensor via photo-induced microscale hyperthermia in situ., PMID:31818758
Ionic liquid and spatially confined gold nanoparticles enhanced photoelectrochemical response of zinc-metal organic frameworks and immunosensing squamous cell carcinoma antigen., PMID:31376714
SCCA-IgM as a Potential Biomarker of Non-Alcoholic Fatty Liver Disease in Patients with Obesity, Prediabetes and Diabetes Undergoing Sleeve Gastrectomy., PMID:31104052
Seed and soil? - Pharyngeal Merkel cell carcinoma after radiotherapy for laryngeal squamous cell carcinoma., PMID:30885449
Facile fabrication of visible light photoelectrochemical immunosensor for SCCA detection based on BiOBr/Bi2S3 heterostructures via self-sacrificial synthesis method., PMID:30876581
Serum Squamous Cell Carcinoma Antigen in Psoriasis: A Potential Quantitative Biomarker for Disease Severity., PMID:29870999
SCCA, TSGF, and the Long Non-Coding RNA AC007271.3 are Effective Biomarkers for Diagnosing Oral Squamous Cell Carcinoma., PMID:29763905
Development of a novel diagnostic algorithm to predict NASH in HCV-positive patients., PMID:29712495
Diagnostic accuracy of SCCA and SCCA-IgM for hepatocellular carcinoma: A meta-analysis., PMID:29704434
Use of protein-based biomarkers of exfoliated cervical cells for primary screening of cervical cancer., PMID:29492827
Characterization of SCCA-IgM as a biomarker of liver disease in an Asian cohort of patients., PMID:29381084
The promise of immunotherapy in anal squamous cell carcinoma: a novel approach for an orphan disease., PMID:29315288
Improved screen-printed carbon electrode for multiplexed label-free amperometric immuniosensor: Addressing its conductivity and reproducibility challenges., PMID:29107882
HPV circulating tumor DNA to monitor the efficacy of anti-PD-1 therapy in metastatic squamous cell carcinoma of the anal canal: A case report., PMID:28670746
Circulating SCCA-IgM complex is a useful biomarker to predict the outcome of therapy in hepatocellular carcinoma patients., PMID:28609160
Squamous Cellular Carcinoma Antigen Serum Determination as a Biomarker of Barrett Esophagus and Esophageal Cancer: A Phase III Study., PMID:28422774
Potential-resolved "in-electrode" type electrochemiluminescence immunoassay based on functionalized g-C3N4 nanosheet and Ru-NH2 for simultaneous determination of dual targets., PMID:28412657
Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study., PMID:28223062
Ultrasensitive electrochemical immunosensor for quantitative detection of SCCA using Co3O4@CeO2-Au@Pt nanocomposite as enzyme-mimetic labels., PMID:28182976
Diagnostic value of serum squamous cell carcinoma antigen for hepatocellular carcinoma: a systematic review and meta-analysis., PMID:27762143
Cancer-associated fibroblasts are an infrequent finding in the microenvironment of proliferative verrucous leukoplakia-associated squamous cell carcinoma., PMID:27681951
An "in-electrode"-type immunosensing strategy for the detection of squamous cell carcinoma antigen based on electrochemiluminescent AuNPs/g-C3N4 nanocomposites., PMID:27591611
Epidermal growth factor receptor inhibition in metastatic anal cancer., PMID:27272412