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Research Grade Cusatuzumab (DHE01901)

Host species:Humanized
Isotype:IgG1-lambda
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHE01901

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-lambda

Clonality

Monoclonal

Target

CD27 ligand, CD70, TNFSF7, CD27LG, CD27L, CD70 antigen, Tumor necrosis factor ligand superfamily member 7, CD27-L

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P32970

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ARGX-110, CAS: 1399546-01-0

Clone ID

Cusatuzumab

Data Image
  • SDS-PAGE
    SDS PAGE for Cusatuzumab
  • Bioactivity
    Detects CD70 in indirect ELISAs.
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents, PMID: 32601337

The CD70 Antibody Cusatuzumab Shows Promise in Acute Myeloid Leukemia, PMID: 34383699

An open-label, non-randomized, Phase Ib feasibility study of cusatuzumab in patients with nasopharyngeal carcinoma, PMID: 34405542

An Update on the Clinical Evaluation of Antibody-Based Therapeutics in Acute Myeloid Leukemia, PMID: 33630233

SAKK 16/14: Durvalumab in Addition to Neoadjuvant Chemotherapy in Patients With Stage IIIA(N2) Non-Small-Cell Lung Cancer-A Multicenter Single-Arm Phase II Trial, PMID: 34251873

Datasheet

Document Download

Research Grade Cusatuzumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Cusatuzumab [DHE01901]
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