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Research Grade Arcitumomab (RHC21001)

Host species:Mouse
Isotype:IgG2a
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

RHC21001

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Target

Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06731

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CEA-Scan, IMMU-4, CAS: 154361-48-5

Clone ID

Arcitumomab

Data Image
  • Bioactivity
    Detects Human CD66e/CEA/CEACAM5 in direct ELISAs.
  • SDS-PAGE
    SDS PAGE for Arcitumomab
References

99m Tc-Arcitumomab, PMID: 20641871

Safety and efficacy of arcitumomab imaging in colorectal cancer after repeated administration, PMID: 10855627

Use of carcinoembryonic antigen radioimmunodetection and computed tomography for predicting the resectability of recurrent colorectal cancer, PMID: 9389396

Radioiodinated T84.66 minibody, PMID: 20641489

Breast cancer imaging with radiolabeled antibodies, PMID: 9990682

Diagnosis of inferior vena cava obstruction on Tc-99m Arcitumomab (CEA scan) scintigraphy, PMID: 9676957

Studies of breast cancer imaging with radiolabeled antibodies to carcinoembryonic antigen. Immunomedics Breast Cancer Study Group, PMID: 9227788

4-[ 18 F]Fluorobenzoyl-T84.66 diabody, PMID: 20641827

111 In-1,4,7,10-Tetraazacyclododecane- N, N', N'', N'''-tetraacetic acid-T84.66 diabody, PMID: 20641644

A prospective study of 2-[18F] fluoro-2-deoxy-D-glucose/positron emission tomography scan, 99mTc-labeled arcitumomab (CEA-scan), and blind second-look laparotomy for detecting colon cancer recurrence in patients with increasing carcinoembryonic antigen levels, PMID: 11776491

In vivo near-infrared fluorescence imaging of carcinoembryonic antigen-expressing tumor cells in mice, PMID: 18413884

111 In-1,4,7,10-Tetraazacyclododecane- N, N', N'', N'''-tetraacetic acid-T84.66 minibody, PMID: 20641400

Can postoperative surveillance with serial CEA immunoscintigraphy detect resectable rectal cancer recurrence and potentially improve tumor-free survival?, PMID: 11085731

Detection of distant medullary thyroid carcinoma metastases by Tc-99m arcitumomab scintigraphy, PMID: 10656657

[Comparative study of CEA antibody scan and computed tomography scan in the follow-up of patients with colorectal cancer], PMID: 12236910

Probe-guided surgery for colorectal cancer, PMID: 10857180

Clinical and technical considerations for imaging colorectal cancers with technetium-99m-labeled antiCEA Fab' fragment, PMID: 10763776

[Personal experience using radioimmunoguided surgery (RIGS)], PMID: 18338553

[Radioimmunoguided surgery (R.I.G.S.) in colorectal cancer. Preliminary results], PMID: 12192927

Is there a role for (99m)Tc-anti-CEA monoclonal antibody imaging in the diagnosis of recurrent colorectal carcinoma?, PMID: 12865871

Bilateral ovarian metastases from colon carcinoma visualized on F-18 FDG PET scan, PMID: 15069335

Phase I/II clinical radioimmunotherapy with an iodine-131-labeled anti-carcinoembryonic antigen murine monoclonal antibody IgG, PMID: 9189130

Immunoscintigraphy and intra-operative radioimmunodetection in the treatment of colorectal carcinoma, PMID: 12790934

Comparative tumor localization of whole immunoglobulin G anticarcinoembryonic antigen monoclonal antibodies IMMU-4 and IMMU-4 F(ab')2 in colorectal cancer patients, PMID: 8306270

FDG PET and immunoscintigraphy with 99mTc-labeled antibody fragments for detection of the recurrence of colorectal carcinoma, PMID: 11037995

Monoclonal antibody imaging in patients with colorectal cancer and increasing levels of serum carcinoembryonic antigen. Experience with ZCE-025 and IMMU-4 monoclonal antibodies and proposed directions for clinical trials, PMID: 8389662

Carcinoembryonic antigen (CEA) scan in the diagnosis of recurrent colorectal carcinoma in a patient with increasing CEA levels and inconclusive computed tomographic findings, PMID: 12819425

Radioimmunodetection of non-small cell lung cancer using technetium-99m-anticarcinoembryonic antigen IMMU-4 Fab' fragment. Preliminary results, PMID: 8306275

Contribution of an Anti-CEA Fab' scan in the detection of medullary thyroid cancer, PMID: 12045444

Incidental detection of carcinoid with Tc-99m-labeled carcinoembryonic antigen monoclonal antibody scintigraphy during evaluation of metastatic colon cancer, PMID: 10595482

Technetium 99m-labeled IMMU-4, a monoclonal antibody against carcinoembryonic antigen, for imaging of occult recurrent colorectal cancer in patients with rising serum carcinoembryonic antigen levels, PMID: 8120546

99Tcm-IMMU4 imaging in recurrent colorectal cancer: efficacy and impact on surgical management, PMID: 8843115

Detection of pelvic recurrence of colorectal carcinoma: prospective, blinded comparison of Tc-99m-IMMU-4 monoclonal antibody scanning and CT, PMID: 7480740

Datasheet

Document Download

Research Grade Arcitumomab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Arcitumomab [RHC21001]
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