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Research Grade Arcitumomab

Catalog #:   RHC21001 Specific References (61) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

RHC21001

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06731

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CEA-Scan, IMMU-4, CAS: 154361-48-5

Clone ID

Arcitumomab

Note

For research use only. Not suitable for clinical or therapeutic use.

Data Image
  • Bioactivity
    Detects Human CD66e/CEA/CEACAM5 in direct ELISAs.
  • SDS-PAGE
    SDS PAGE for Arcitumomab
References

Monoclonal antibody imaging in patients with colorectal cancer and increasing levels of serum carcinoembryonic antigen. Experience with ZCE-025 and IMMU-4 monoclonal antibodies and proposed directions for clinical trials., PMID:8389662

Comparative tumor localization of whole immunoglobulin G anticarcinoembryonic antigen monoclonal antibodies IMMU-4 and IMMU-4 F(ab')2 in colorectal cancer patients., PMID:8306270

Radioimmunodetection of non-small cell lung cancer using technetium-99m-anticarcinoembryonic antigen IMMU-4 Fab' fragment. Preliminary results., PMID:8306275

Technetium 99m-labeled IMMU-4, a monoclonal antibody against carcinoembryonic antigen, for imaging of occult recurrent colorectal cancer in patients with rising serum carcinoembryonic antigen levels., PMID:8120546

Detection of pelvic recurrence of colorectal carcinoma: prospective, blinded comparison of Tc-99m-IMMU-4 monoclonal antibody scanning and CT., PMID:7480740

99Tcm-IMMU4 imaging in recurrent colorectal cancer: efficacy and impact on surgical management., PMID:8843115

Studies of breast cancer imaging with radiolabeled antibodies to carcinoembryonic antigen. Immunomedics Breast Cancer Study Group., PMID:9227788

Phase I/II clinical radioimmunotherapy with an iodine-131-labeled anti-carcinoembryonic antigen murine monoclonal antibody IgG., PMID:9189130

Use of carcinoembryonic antigen radioimmunodetection and computed tomography for predicting the resectability of recurrent colorectal cancer., PMID:9389396

Diagnosis of inferior vena cava obstruction on Tc-99m Arcitumomab (CEA scan) scintigraphy., PMID:9676957

Breast cancer imaging with radiolabeled antibodies., PMID:9990682

Incidental detection of carcinoid with Tc-99m-labeled carcinoembryonic antigen monoclonal antibody scintigraphy during evaluation of metastatic colon cancer., PMID:10595482

Detection of distant medullary thyroid carcinoma metastases by Tc-99m arcitumomab scintigraphy., PMID:10656657

Clinical and technical considerations for imaging colorectal cancers with technetium-99m-labeled antiCEA Fab' fragment., PMID:10763776

Safety and efficacy of arcitumomab imaging in colorectal cancer after repeated administration., PMID:10855627

Probe-guided surgery for colorectal cancer., PMID:10857180

FDG PET and immunoscintigraphy with 99mTc-labeled antibody fragments for detection of the recurrence of colorectal carcinoma., PMID:11037995

Can postoperative surveillance with serial CEA immunoscintigraphy detect resectable rectal cancer recurrence and potentially improve tumor-free survival?, PMID:11085731

A prospective study of 2-[18F] fluoro-2-deoxy-D-glucose/positron emission tomography scan, 99mTc-labeled arcitumomab (CEA-scan), and blind second-look laparotomy for detecting colon cancer recurrence in patients with increasing carcinoembryonic antigen levels., PMID:11776491

Contribution of an Anti-CEA Fab' scan in the detection of medullary thyroid cancer., PMID:12045444

[Radioimmunoguided surgery (R.I.G.S.) in colorectal cancer. Preliminary results]., PMID:12192927

[Comparative study of CEA antibody scan and computed tomography scan in the follow-up of patients with colorectal cancer]., PMID:12236910

Immunoscintigraphy and intra-operative radioimmunodetection in the treatment of colorectal carcinoma., PMID:12790934

Carcinoembryonic antigen (CEA) scan in the diagnosis of recurrent colorectal carcinoma in a patient with increasing CEA levels and inconclusive computed tomographic findings., PMID:12819425

Is there a role for (99m)Tc-anti-CEA monoclonal antibody imaging in the diagnosis of recurrent colorectal carcinoma?, PMID:12865871

Bilateral ovarian metastases from colon carcinoma visualized on F-18 FDG PET scan., PMID:15069335

[Personal experience using radioimmunoguided surgery (RIGS)]., PMID:18338553

In vivo near-infrared fluorescence imaging of carcinoembryonic antigen-expressing tumor cells in mice., PMID:18413884

Detection of pelvic recurrence of colorectal carcinoma: prospective, blinded comparison of Tc-99m-IMMU-4 monoclonal antibody scanning and CT, PMID: 7480740

99Tcm-IMMU4 imaging in recurrent colorectal cancer: efficacy and impact on surgical management, PMID: 8843115

Technetium 99m-labeled IMMU-4, a monoclonal antibody against carcinoembryonic antigen, for imaging of occult recurrent colorectal cancer in patients with rising serum carcinoembryonic antigen levels, PMID: 8120546

Incidental detection of carcinoid with Tc-99m-labeled carcinoembryonic antigen monoclonal antibody scintigraphy during evaluation of metastatic colon cancer, PMID: 10595482

Contribution of an Anti-CEA Fab' scan in the detection of medullary thyroid cancer, PMID: 12045444

Radioimmunodetection of non-small cell lung cancer using technetium-99m-anticarcinoembryonic antigen IMMU-4 Fab' fragment. Preliminary results, PMID: 8306275

Carcinoembryonic antigen (CEA) scan in the diagnosis of recurrent colorectal carcinoma in a patient with increasing CEA levels and inconclusive computed tomographic findings, PMID: 12819425

Monoclonal antibody imaging in patients with colorectal cancer and increasing levels of serum carcinoembryonic antigen. Experience with ZCE-025 and IMMU-4 monoclonal antibodies and proposed directions for clinical trials, PMID: 8389662

FDG PET and immunoscintigraphy with 99mTc-labeled antibody fragments for detection of the recurrence of colorectal carcinoma, PMID: 11037995

Comparative tumor localization of whole immunoglobulin G anticarcinoembryonic antigen monoclonal antibodies IMMU-4 and IMMU-4 F(ab')2 in colorectal cancer patients, PMID: 8306270

Immunoscintigraphy and intra-operative radioimmunodetection in the treatment of colorectal carcinoma, PMID: 12790934

Phase I/II clinical radioimmunotherapy with an iodine-131-labeled anti-carcinoembryonic antigen murine monoclonal antibody IgG, PMID: 9189130

Bilateral ovarian metastases from colon carcinoma visualized on F-18 FDG PET scan, PMID: 15069335

Is there a role for (99m)Tc-anti-CEA monoclonal antibody imaging in the diagnosis of recurrent colorectal carcinoma?, PMID: 12865871

[Radioimmunoguided surgery (R.I.G.S.) in colorectal cancer. Preliminary results], PMID: 12192927

[Personal experience using radioimmunoguided surgery (RIGS)], PMID: 18338553

Clinical and technical considerations for imaging colorectal cancers with technetium-99m-labeled antiCEA Fab' fragment, PMID: 10763776

Probe-guided surgery for colorectal cancer, PMID: 10857180

[Comparative study of CEA antibody scan and computed tomography scan in the follow-up of patients with colorectal cancer], PMID: 12236910

Detection of distant medullary thyroid carcinoma metastases by Tc-99m arcitumomab scintigraphy, PMID: 10656657

Can postoperative surveillance with serial CEA immunoscintigraphy detect resectable rectal cancer recurrence and potentially improve tumor-free survival?, PMID: 11085731

111 In-1,4,7,10-Tetraazacyclododecane- N, N', N'', N'''-tetraacetic acid-T84.66 minibody, PMID: 20641400

In vivo near-infrared fluorescence imaging of carcinoembryonic antigen-expressing tumor cells in mice, PMID: 18413884

A prospective study of 2-[18F] fluoro-2-deoxy-D-glucose/positron emission tomography scan, 99mTc-labeled arcitumomab (CEA-scan), and blind second-look laparotomy for detecting colon cancer recurrence in patients with increasing carcinoembryonic antigen levels, PMID: 11776491

111 In-1,4,7,10-Tetraazacyclododecane- N, N', N'', N'''-tetraacetic acid-T84.66 diabody, PMID: 20641644

4-[ 18 F]Fluorobenzoyl-T84.66 diabody, PMID: 20641827

Studies of breast cancer imaging with radiolabeled antibodies to carcinoembryonic antigen. Immunomedics Breast Cancer Study Group, PMID: 9227788

Diagnosis of inferior vena cava obstruction on Tc-99m Arcitumomab (CEA scan) scintigraphy, PMID: 9676957

Breast cancer imaging with radiolabeled antibodies, PMID: 9990682

Radioiodinated T84.66 minibody, PMID: 20641489

Use of carcinoembryonic antigen radioimmunodetection and computed tomography for predicting the resectability of recurrent colorectal cancer, PMID: 9389396

Safety and efficacy of arcitumomab imaging in colorectal cancer after repeated administration, PMID: 10855627

99m Tc-Arcitumomab, PMID: 20641871

Datasheet

Document Download

Research Grade Arcitumomab.pdf

 

$ 320
Product specifications
100 μg 320 1 mg 1280 5 mg 3840

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Arcitumomab [RHC21001]
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