Catalog No.
EHE10801
Expression system
Insect Cells
Species
Homo sapiens (Human)
Protein length
Met1-Asp380
Predicted molecular weight
50 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35414
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
G-protein coupled receptor HG11, Apelin receptor, AGTRL1, APJ, Angiotensin receptor-like 1, APLNR, G-protein coupled receptor APJ
Targeted delivery of apelin using a novel extracellular vesicle platform for pulmonary arterial hypertension treatment., PMID:40449081
Insights into the function and research status of membrane protein APJ., PMID:40419033
Immunohistochemistry and molecular biology studies of apelin and apelin receptor in queen placenta., PMID:40392420
ELABELA-32 Alleviates Doxorubicin-Induced Chronic Cardiotoxicity by Inhibiting the TGF-β/Smad Signaling Pathway., PMID:40389799
Goldfish phoenixin: (I) structural characterization, tissue distribution, and novel function as a feedforward signal for feeding-induced food intake in fish model., PMID:40365230
Multiscale biased chemical space remodeling for developing APLNR agonists with anti-HFpEF efficacy., PMID:40314976
Apelinergic System in the Left Ventricle Adverse Remodeling After Myocardial Infarction: A Preliminary Study., PMID:40297796
Click-Functionalized Cyanine Fluorogenic Dimers for Improved Detection of GPCRs: Application to Imaging of ApelinR in Living Cells., PMID:40273184
Apelin/APJ: Another Player in the Cancer Biology Network., PMID:40243599
Adipokines level in plasma, hypothalamus, ovaries and adipose tissue of rats with polycystic ovary syndrome., PMID:40199655
Characterization of key genes and immune cell infiltration associated with endometriosis through integrating bioinformatics and experimental analyses., PMID:40165344
Apelin-13/APJ promotes neural stem cells to repair ischemic stroke., PMID:40164018
Saponins from Aralia taibaiensis protect against brain ischemia/reperfusion injuries by regulating the apelin/AMPK pathway., PMID:40122660
Apelin/APJ alleviates diabetic nephropathy by improving glomerular endothelial cells dysfunction via SIRT3‑KLF15., PMID:40052569
Repression of apelin Furin cleavage sites provides antimetastatic strategy in colorectal cancer., PMID:39962271
Cxcl9 modulates aging associated microvascular metabolic and angiogenic dysfunctions in subcutaneous adipose tissue., PMID:39934436
SEC62-dependent ER-phagy contributes to apelin-13/APJ-induced monocyte-vascular endothelial cell adhesion in atherosclerosis pathogenesis., PMID:39930135
In vitro effect of omentin-1 on level of other adipokines in granulosa cells from ovaries of Large White and Meishan pigs., PMID:39889341
Metabolically stable apelin analogs: development and functional role in water balance and cardiovascular function., PMID:39879076
Advances in the therapeutic potentials of ligands of the apelin receptor APJ., PMID:39870231
Evaluation of Structure Prediction and Molecular Docking Tools for Therapeutic Peptides in Clinical Use and Trials Targeting Coronary Artery Disease., PMID:39859178
Identification and Immunological Characterization of Cuproptosis Related Genes in Preeclampsia Using Bioinformatics Analysis and Machine Learning., PMID:39853851
Activation of APJ Receptors by CMF-019, But Not Apelin, Causes Endothelium-Dependent Relaxation of Spontaneously Hypertensive Rat Coronary Arteries., PMID:39836102
A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor., PMID:39800176
Structural insights into the regulation of monomeric and dimeric apelin receptor., PMID:39747115
Liver B Cells Promotes MASLD Progression via the Apelin/APLNR System., PMID:39744169
Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor., PMID:39730334
Targeting APJ drives BNIP3-PINK1-PARKIN induced mitophagy and improves systemic inflammatory bone loss., PMID:39725007
A Morphological and Behavioral Study of Demyelination and Remyelination in the Cuprizone Model: Insights into APLNR and NG2+ Cell Dynamics., PMID:39684720
The Metabolically Resistant Apelin-17 Analogue LIT01-196 Reduces Cardiac Dysfunction and Remodelling in Heart Failure After Myocardial Infarction., PMID:39674544
The future of G protein-coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design., PMID:39658529
Apelin/APJ increased renal blood flow through endothelial BKCa channel induced p-eNOS and ET-1 in diabetic conditions., PMID:39644975
Cellular and molecular mechanisms of action of ovarian steroid hormones II: Regulation of sexual behavior in female rodents., PMID:39571668
Divergent roles of DRY and NPxxY motifs in selective activation of downstream signalling by the apelin receptor., PMID:39513765
Activation of the apelin/APJ system by vitamin D attenuates age-related muscle atrophy., PMID:39488262
Apelin/APJ signaling in IGF-1-induced acute mitochondrial and antioxidant effects in spontaneously hypertensive rat myocardium., PMID:39453580
Single-cell and spatial transcriptomics reveal apelin/APJ pathway's role in microvessel formation and tumour progression in hepatocellular carcinoma., PMID:39434201
Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control., PMID:39358374
Expression of the apelin system in the porcine pituitary during the oestrous cycle and early pregnancy and the effect of apelin on LH and FSH secretion., PMID:39357165
Cholecystokinin regulates atrial natriuretic peptide secretion through activation of NOX4-Sirt1-LEF1 signaling in beating rat hypoxic atria., PMID:39326462
Inflammatory Intracellular Signaling in Neurons Is Influenced by Glial Soluble Factors in iPSC-Based Cell Model of PARK2-Associated Parkinson's Disease., PMID:39273568
Silencing APLNR enhances the radiosensitivity of prostate cancer by modulating the PI3K/AKT/mTOR signaling pathway., PMID:39251496
The Elabela-APJ axis attenuates sepsis-induced myocardial dysfunction by reducing pyroptosis by balancing the formation and degradation of autophagosomes., PMID:39241986
Endothelialized Bronchioalveolar Lung Organoids Model Endothelial Cell Responses to Injury., PMID:39226154
Apelinergic system in acute kidney injury: Mechanistic insights and therapeutic potential., PMID:39217720
Apelin - A New Kid on the Block in Periodontology., PMID:39189510
Exploring the potential roles of apelin, visfatin, and irisin in energy regulation in farm animals: an overview., PMID:39109340
Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis., PMID:39060233
Apelin Receptor Homodimerisation Inhibits Hippocampal Neuronal Autophagy via G Protein-Dependent Signalling in Vascular Dementia., PMID:39042220
The adipokine profile in the plasma and anterior pituitary of pigs during the estrous cycle., PMID:39013539
For research use only. Not for human or drug use.
